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Binsch, O. (author), Bottenheft, C. (author), Landman, A. (author), Roijendijk, L. (author), Vermetten, E.H.G.J.M. (author)The current study explores whether different stressors in a virtual reality (VR) military training scenario cause increases in physiological stress. This would validate the use of VR simulation for stress training, as well as the physiological monitoring of trainees for educational purposes. Military cadets (n = 63) performed a patrol scenario ...article 2021
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Pasma, W. (author), Wesselink, E.M. (author), van Buuren, S. (author), de Graaff, J.C. (author), van Klei, W.A. (author)Physiologic data from anesthesia monitors are automatically captured. Yet erroneous data are stored in the process as well. While this is not interfering with clinical care, research can be affected. Researchers should find ways to remove artifacts. The aim of the present study was to compare different artifact annotation strategies, and to...article 2021
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Humalda, J.K. (author), Klaassen, G. (author), de Vries, H. (author), Meuleman, Y. (author), Verschuur, L.C. (author), Straathof, E.J.M. (author), Laverman, G.D. (author), Bos, W.J.W. (author), van der Boog, P.J.M. (author), Vermeulen, K.M. (author), Blanson Henkemans, O.A. (author), Otten, W. (author), de Borst, M.H. (author), van Dijk, S. (author), Navis, G.J. (author)Rationale & objective: Patients with chronic kidney disease (CKD) are particularly sensitive to dietary sodium. We evaluated a self-management approach for dietary sodium restriction in patients with CKD. Study design: Randomized controlled trial. Setting & participants: Nephrology outpatient clinics in 4 Dutch hospitals. 99 adults with CKD...article 2020
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Pasma, W. (author), Peelen, L.M. (author), van den Broek, S. (author), van Buuren, S. (author), van Klei, W.A. (author), de Graaff, J.C. (author)Background: Intraoperative blood pressure has been suggested as a key factor for safe pediatric anesthesia. However, there is not much insight into factors that discriminate between children with low and normal pre-incision blood pressure. Our aim was to explore whether children who have a low blood pressure during anesthesia are different than...article 2020
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van Beurden, M. (author), Brouwer, A.M. (author), van Baardewijk, J.U. (author), Binsch, O. (author), Vermetten, E. (author), Roijendijk, L. (author)Feedback of physiological responses have a great potential to support virtual training paradigms aimed to increase cognitive task performance under stressful threatening conditions. In the current study, we examined the sensitivity of a range of physiological indicators derived from electrodermal activity (EDA), blood pressure (BP) and heart...article 2020
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Beijers, R.J.H.C.G. (author), Huysmans, S.M.D. (author), van de Bool, C. (author), Kingma, B.R.M. (author), Verdijk, A.B. (author), Loon, L.J.C. (author), Meex, S.J.R. (author), Gosker, H.R. (author), Schols, A.M.W.J. (author)Background & aims : Many COPD patients have a reduced exercise capacity and mechanical efficiency and are at increased cardiometabolic risk. This study aimed to assess acute and 7-days effects of dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with COPD. Methods : This double-blind, randomized...article 2018
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Viester, L. (author), Verhagen, E.A.L.M. (author), Bongers, P.M. (author), van der Beek, A.J. (author)Purpose: To evaluate the effectiveness of an individually tailored intervention for improvement in lifestyle behavior, health indicators, and prevention and reduction of overweight among construction workers. Design: Randomized controlled trial. Setting: Various blue-collar departments of a large construction company in the Netherlands....article 2018
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van den Broek, T.J. (author), Bakker, G.C.M. (author), Rubingh, C.M. (author), Bijlsma, S. (author), Stroeve, J.H.M. (author), van Ommen, B. (author), van Erk, M.J. (author), Wopereis, S. (author)Background: A key feature of metabolic health is the ability to adapt upon dietary perturbations. A systemic review defined an optimal nutritional challenge test, the "PhenFlex test" (PFT). Recently, it has been shown that the PFT enables the quantification of all relevant metabolic processes involved in maintaining or regaining homeostasis of...article 2017
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Sharma, M.K. (author), Wieringa, F.P. (author), Frijns, A.J.H. (author), Kooman, J.P. (author)Introduction: End-stage renal disease (ESRD) patients depend on dialysis for removal of toxic waste products, fluid overload relief and maintenance of electrolyte balance. Dialysis prolongs millions of lives. To some extent, ESRD has become a manageable disease with a steadily growing dialysis population of increasing average age and associated...article 2016
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Stroeve, J.H.M. (author), Saccenti, E. (author), Bouwman, J. (author), Dane, A. (author), Strassburg, K. (author), Vervoort, J. (author), Hankemeier, T. (author), Astrup, A. (author), Smilde, A.K. (author), van Ommen, B. (author), Saris, W.H.M. (author)Objective: Aim is to predict successful weight loss by metabolic signatures at baseline and to identify which differences in metabolic status may underlie variations in weight loss success. Methods: In DiOGenes, a randomized, controlled trial, weight loss was induced using a low calorie diet (800 kcal) for 8-weeks. Men (N5236) and women (N5431)...article 2016
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TNO Kwaliteit van Leven (author), Oki, T. (author), Kano, M. (author), Watanabe, O. (author), Goto, K. (author), Boelsma, E. (author), Ishikawa, F. (author), Suda, I. (author)An open-label study with one treatment arm was conducted to investigate changes in health-related biomarkers (blood pressure and liver enzyme activity) and the safety of 4 weeks of consuming a purple-fleshed sweet potato beverage in Caucasian subjects. Twenty healthy adults, 18-70 years of age, with a body mass index > 25 kg/m2, elevated blood...article 2016
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van Lint, C.L. (author), van der Boog, P.J.M. (author), Wang, W. (author), Brinkman, W.P. (author), Rövekamp, T.J.M. (author), Neerincx, M.A. (author), Rabelink, T.J. (author), van Dijk, S. (author)Background: After a kidney transplantation, patients have to visit the hospital often to monitor for early signs of graft rejection. Self-monitoring of creatinine in addition to blood pressure at home could alleviate the burden of frequent outpatient visits, but only if patients are willing to self-monitor and if they adhere to the self...article 2015
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Luger, T. (author), Bosch, T. (author), Veeger, D. (author), de Looze, M. (author)Task variation has been proposed to reduce shoulder fatigue resulting from repetitive hand-arm tasks. This review analyses the effect of task variation, both 'temporal (i.e. change of work-rest ratio)' and 'activity (i.e. job rotation)' variation, on physiological responses, endurance time (ET) and subjective feelings. Pubmed was searched and...article 2014
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van den Berg, E. (author), Engberink, M.F. (author), Brink, E.J. (author), van Baak, M.A. (author), Gans, R.O.B. (author), Navis, G. (author), Bakker, S.J.L. (author)Hypertension is highly prevalent among renal transplant recipients (RTR) and a risk factor for graft failure and cardiovascular events. Protein intake has been claimed to affect blood pressure (BP) in the general population and may affect renal function. We examined the association of dietary protein with BP and renal function in RTR. We...article 2013
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van den Berg, E. (author), Geleijnse, J.M. (author), Brink, E.J. (author), van Baak, M.A. (author), Homan van der Heide, J.J. (author), Gans, R.O.B. (author), Navis, G. (author), Bakker, S.J.L. (author)Background. Hypertension is common among renal transplant recipients (RTR) and a risk factor for graft failure and mortality. Sodium intake is a well-established determinant of blood pressure (BP) in the general population. However, data in RTR are limited. International guidelines recommend a maximum daily sodium intake of 70 mmol. We...article 2012
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Janssens, A.C.J.W. (author), Henneman, L. (author), Detmar, S.B. (author), Khoury, M.J. (author), Steyerberg, E.W. (author), Eijkemans, M.J.C. (author), Mushkudiani, N. (author), Oostra, B.A. (author), van Duijn, C.M. (author), MacKenbach, J.P. (author)Objective: We investigated the accuracy of self-reported family history for diabetes, hypertension, and overweight against two reference standards: family history based on physician-assessed health status of relatives and on self-reported personal health status of relatives. Study Design and Setting: Subjects were participants from the Erasmus...article 2012
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van den Hooven, E.H. (author), de Kluizenaar, Y. (author), Pierik, F.H. (author), Hofman, A. (author), van Ratingen, S.W. (author), Zandveld, P.Y.J. (author), MacKenbach, J.P. (author), Steegers, E.A.P. (author), Miedema, H.M.E. (author), Jaddoe, V.W.V. (author)Exposure to air pollution is associated with elevated blood pressure and cardiovascular disease. We assessed the associations of exposure to particulate matter (PM10) and nitrogen dioxide (NO2) levels with blood pressure measured in each trimester of pregnancy and the risks of pregnancy-induced hypertension and preeclampsia in 7006 women...article 2011
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TNO Kwaliteit van Leven (author), Altorf, W. (author), van der Kuil, W.A. (author), Engberink, M.F. (author), Brink, E.J. (author), van Baak, M.A. (author), Bakker, S.J.L. (author), Navis, G. (author), van't Veer, P. (author), Geleijnse, J.M. (author)Background: Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP. We performed a systematic review of all published scientific literature on dietary protein, including protein from various sources, in relation...article 2010
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TNO Kwaliteit van Leven (author), Boelsma, E. (author), Kloek, J. (author)Background. Milk derived peptides have been identified as potential antihypertensive agents. The primary objective was to investigate the effectiveness of IPP-rich milk protein hydrolysates (MPH) on reducing blood pressure (BP) as well as to investigate safety parameters and tolerability. The secondary objective was to confirm or falsify ACE...article 2010
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Ponstein-Simarro Doorten, A.Y. (author), van de Wiel, J.A.G. (author), Jonker, D. (author), TNO Kwaliteit van Leven (author)Tensguard™ is a milk protein hydrolysate containing the lactotripeptide IPP. It is derived from cow's milk, which is present in the human diet and has a safe history of consumption. The final Tensguard™ product, a supplement or a functional food ingredient, is intended for use by people who want to follow a healthy diet and lifestyle in order to...article 2009