Impaired prenatal and postnatal growth in Dutch patients with phenylketonuria

Objective - To assess whether physical growth is affected in early treated Dutch patients with phenylketonuria (PKU). Methods - The birth weights of all 137 early detected patients with PKU born in the period from 1974 to 1988 in the Netherlands were compared with reference values. Height, head circumference, and weight were measured at the age...

Percentielgrenzen voor geboortegewicht van vroeggeborenen moeten worden herzien [The birthweight percentiles of preterm infants need to be updated]

Objective. To analyse whether the conventional so-called Kloosterman charts for birthweight of preterm infants based on data from 1931-1965 are still valid. Design. Descriptive investigation. Location. The Netherlands. Methods. Data were obtained from the 'project of the premature and small for gestational age' (POPS) survey in 1983. The...

School performance at nine years of age in very premature and very low birth weight infants: Perinatal risk factors and predictors at five years of age

To assess the impact of both perinatal disorders and developmental problems identified at preschool age on school performance, we followed a virtually complete birth cohort of very premature (<32 completed weeks of gestation) and very low birth weight infants until they were 9 years of age. In 84% of the survivors (n = 813), data on school...

Differential misclassification of alcohol and cigarette consumption by pregnancy outcome

Background. The validity of the results of studies using retrospectively collected information on exposures is often criticized, because cases may report differently from controls even if their true exposure status is the same. This study was performed to quantify the extent to which this effect (differential misclassification) may occur for...

Social class, ethnicity and other risk factors for small for gestational age and preterm delivery in the Netherlands

Social class and ethnicity are important risk factors for small-for-gestational-age and preterm delivery in many countries. This study was performed to assess whether this is also the case in the Netherlands, a country with a high level of social security, relatively small income differences and easy access to medical care for all its...

Prediction of height achievement at five years of age in children born very preterm or with very low birth weight: Continuation of catch-up growth after two years of age

To predict height at five years in a cohort of 565 very preterm and/or very low-birth-weight children, hypothesized growth determinants were subjected to discriminant analysis. Many neonatal parameters were not significantly associated with short stature at five years of age. A correct classification of stature (smaller/larger than the 10th...

DES and preterm birth rate [1]

Chemicals/CAS: diethylstilbestrol, 30498-85-2, 56-53-1; Diethylstilbestrol, 56-53-1

Verloskundige uitkomsten tienerzwangerschappen in Nederland [Obstetric data on teenage pregnancies in the Netherlands]

The objective was to compare the course of teenage pregnancies and deliveries with those of women between the ages of 20 and 29, using data from the 1989 National Obstetric Database (LVR) when approximately 76% of cases conducted by obstetricians were registered. 4500 teenage pregnancies were studied to compare the risk of preterm birth, low...

Evaluation of care for the preterm infant: Review of literature on follow-up of preterm and low birthweight infants : Report from the collaborative Project On Preterm and Small for gestational age infants (POPS) in The Netherlands

Since the introduction of neonatal intensive care in the 1960s, mortality in very preterm and very low birthweight infants has been decreasing steadily. Consequently, interest in the outcome of surviving infants is growing. Restriction of health care resources has stressed the need for information concerning the effect of individual treatment...

Transient hypothyroxinaemia associated with developmental delay in very preterm infants

In 563 surviving very preterm (<32 weeks gestational age) and/or very low birthweight (<1500 g) infants the relationship between neonatal thyroxine concentration and psychomotor development at 2 years of age (corrected for preterm birth) was studied. A significant association was found between low neonatal thyroxine concentration and a negative...

The male disadvantage in very low birthweight infants: Does it really exist?

In a nationwide collaborative study in the Netherlands, perinatal and follow up data were collected on 1338 liveborn very preterm (<32 weeks) and/or very low birth-weight (VLBW) infants (<1500g). In this group, the mortality risk was similar for both male and female infants. The handicap risk, however, was significantly greater for boys than for...