Searched for: subject%3A%22Biological%255C%2Bactivity%22
(1 - 8 of 8)
document
Verhoeckx, K. (author), Bogh, K.L. (author), Dupont, D. (author), Egger, L. (author), Gadermaier, G. (author), Larre, C. (author), Mackie, A. (author), Menard, O. (author), Adel-Patient, K. (author), Picariello, G. (author), Portmann, R. (author), Smit, J. (author), Turner, P. (author), Untersmayr, E. (author), Epstein, M.M. (author)
The current allergenicity assessment of novel proteins is based on the EFSA GMO guidance. Recently, EFSA launched a new guidance document on allergenicity assessment of GM plants (2017). This document describes, amongst other topics, the new scientific and regulatory developments on in vitro protein digestibility tests. The EFSA GMO Panel stated...
article 2019
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van Ommen, B. (author), van den Broek, T. (author), de Hoogh, I. (author), van Erk, M. (author), van Someren, E. (author), Rouhani-Rankouhi, T. (author), Anthony, J.C. (author), Hogenelst, K. (author), Pasman, W. (author), Boorsma, A. (author), Wopereis, S. (author)
Personalized nutrition is fast becoming a reality due to a number of technological, scientific, and societal developments that complement and extend current public health nutrition recommendations. Personalized nutrition tailors dietary recommendations to specific biological requirements on the basis of a person’s health status and goals. The...
article 2017
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van Uhm, J.I.M. (author), Visser, G.W.M. (author), van der Schans, M.J. (author), Geldof, A.A. (author), Meuleman, E.J.H. (author), Nieuwenhuijzen, J.A. (author)
Background: Botulinum neurotoxin A (BoNT-A) is a highly neurotoxic drug and frequently used in patients. Knowledge on the optimal way of administration of BoNT-A and its subsequent distribution is still rather limited. An accurate method for monitoring these processes might be the use of radiolabelled BoNT-A. In this paper, we report our...
article 2015
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Blatchford, P. (author), Ansell, J. (author), de Godoy, M.R.C. (author), Fahey, G. (author), Garcia-Mazcorro, J.F. (author), Gibson, G.R. (author), Goh, Y.J. (author), Hotchkiss, A.T. (author), Hutkins, R. (author), LaCroix, C. (author), Rastall, R.A. (author), Reimer, R.A. (author), Schoterman, M. (author), Van Sinderen, D. (author), Venema, K. (author), Whelan, K. (author)
In October 2012, a group of scientists met at the 10th Meeting of the International Scientific Association of Probiotics and Prebiotics (ISAPP) in Cork, Ireland to discuss issues surrounding prebiotics and their development. This article summarises outputs from the meeting. Various prebiotic definitions were discussed and how the concept has...
article 2013
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TNO Bouw en Ondergrond (author), Hultin, K.A.H. (author), Nilsson, E.D. (author), Krejci, R. (author), Mrtensson, E.M. (author), Ehn, M. (author), Hagström, Å. (author), de Leeuw, G. (author)
Bubbles bursting from whitecaps are considered to be the most effective mechanism for particulate matter to be ejected into the atmosphere from the Earth's oceans. To realistically predict the climate effect of marine aerosols, global climate models require process-based understanding of particle formation from bubble bursting. During a cruise...
article 2010
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Kienhuis, A.S. (author), van de Poll, M.C.G. (author), Wortelboer, H. (author), van Herwijnen, M. (author), Gottschalk, R. (author), de Jong, C.H.C. (author), Boorsma, A. (author), Paules, R.S. (author), Kleinjans, J.C.S. (author), Stierum, R.H. (author), van Delft, J.H.M. (author), TNO Kwaliteit van Leven (author)
The frequent use of rodent hepatic in vitro systems in pharmacological and toxicological investigations challenges extrapolation of in vitro results to the situation in vivo and interspecies extrapolation from rodents to humans. The toxicogenomics approach may aid in evaluating relevance of these model systems for human risk assessment by direct...
article 2009
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Ladics, G.S. (author), van Bilsen, J.H.M. (author), Brouwer, H.M.H. (author), Vogel, L. (author), Vieths, S. (author), Knippels, L.M.J. (author), TNO Kwaliteit van Leven (author), KvL (author)
Specific IgE sera screening studies are employed to investigate protein cross-reactivity. Such nonfunctional immunochemical methods cannot measure the biological activity of proteins. Therefore, an assay using RBL cells transfected with human FcεRI was developed. Our objective was to evaluate the degranulation of three cell-lines expressing...
article 2008
document
TNO Voeding (author), van der Woude, H. (author), Alink, G.M. (author), van Rossum, B.E.J. (author), Walle, K. (author), van Steeg, H. (author), Walle, T. (author), Rietjens, I.M.C.M. (author)
This study investigates the role of cellular tyrosinase and/or peroxidase-like oxidative enzyme activity in the covalent binding of quercetin to glutathione, protein, and DNA, as well as the stability of quercetin DNA adducts in time. This was done by studying the formation of glutathionyl quercetin adducts in various in vitro models, and the...
article 2005
Searched for: subject%3A%22Biological%255C%2Bactivity%22
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