Searched for: subject%3A%22Biological%255C%2BAssay%22
(1 - 10 of 10)
document
Luijten, M. (author), Olthof, E.D. (author), Hakkert, B.C. (author), Rorije, E. (author), van der Laan, J.-W. (author), Woutersen, R.A. (author), van Benthem, J. (author)
Assessment of genotoxic and carcinogenic potential is considered one of the basic requirements when evaluating possible human health risks associated with exposure to chemicals. Test strategies currently in place focus primarily on identifying genotoxic potential due to the strong association between the accumulation of genetic damage and cancer...
article 2016
document
Engelse, M.A. (author), Laurens, N. (author), Verloop, R.E. (author), Koolwijk, P. (author), van Hinsbergh, V.W.M. (author), TNO Kwaliteit van Leven (author)
The formation of new tubular structures from a quiescent endothelial lining is one of the hallmarks of sprouting angiogenesis. This process can be mimicked in vitro by inducing capillary-like tubular structures in a three-dimensional (3D) fibrin matrix. We aimed to analyze the differential mRNA expression in two phenotypically distinct cell...
article 2008
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Blankvoort, B.M.G. (author), Aarts, J.M.M.J.G. (author), Schilt, R. (author), Geerdink, P. (author), Spenkelink, B. (author), Rodenburg, R.J.T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Despite a ban by the European Union, the use of anabolic steroids and repartitioning agents in cattle is still occasionally observed. Due to continuing improvements in analytical techniques, very low detection limits for individual compounds have been achieved. In response to these developments, cocktails composed of several steroids have been...
article 2003
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Feron, V.J. (author), Schwarz, M. (author), Hemminki, K. (author), Krewski, D. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
article 1999
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Gaubius Instituut TNO (author), Beekman, B. (author), van El, B. (author), Drijfhout, J.W. (author), Ronday, H.K. (author), TeKoppele, J.M. (author)
Stromelysin-1 (MMP-3) is an important member of the matrix metalloproteinase family. In joint-degrading diseases like arthritis, elevated levels of MMP-3 protein are detected in synovial fluid using immunological methods. However, these methods do not discriminate between active and inactive enzyme. In the present study, a specific stromelysin...
article 1997
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Kroes, R. (author), Instituut CIVO-Toxicologie en voeding TNO (author)
Short-term tests designed to detect possible carcinogenicity have been extensively refined during the last years. Presently, many more or less simple and convenient systems are available to detect mutations, chromosome effects, DNA damage, and malignant transformation. Although their relevance to carcinogenicity is often reasonably good,...
article 1983
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Radiobiologisch Instituut TNO (author), Hermens, A.F. (author)
article 1980
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Molenaar, P.C. (author), Polak, R.L. (author), Nickolson, V.J. (author), Medisch Biologisch Laboratorium TNO (author)
Slices from rat brain cortex were incubated for either 5 or 60 min in a medium containing [3H]choline and 4.7 or 25 mM KCl. Bioassayable ACh and labelled ACh were determined in the incubation medium, in the total tissue homogenate and in subcellular fractions. Raising the KCl concentration from 4.7 to 25 mM stimulated the release and synthesis...
article 1973
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Centraal Instituut voor Voedingsonderzoek TNO (author), de Waart, J. (author)
Chemicals/CAS: 3 nitropropionic acid, 504-88-1; aflatoxin B1, 1162-65-8; aflatoxin B2, 7220-81-7; aflatoxin G1, 1165-39-5; aflatoxin G2, 7241-98-7; aflatoxin, 1402-68-2; diacetoxyscirpenol, 2270-40-8; fumagillin, 23110-15-8; gliotoxin, 37273-88-4, 67-99-2; kojic acid, 501-30-4; luteoskyrin, 21884-44-6; ochratoxin, 303-47-9, 37203-43-3;...
article 1973
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Offers, S. (author), Bentvelzen, P. (author), Radiobiologisch Instituut TNO (author)
article 1971
Searched for: subject%3A%22Biological%255C%2BAssay%22
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