Searched for: subject%3A%22Biocompatibility%22
(1 - 13 of 13)
document
Langerak, N. (author), Ahmed, H.M.M. (author), Li, Y. (author), Middel, I.R. (author), eslami Amirabadi, H. (author), Malda, J. (author), Masereeuw, R. (author), van Roij, R. (author)
Microphysiological systems have potential as test systems in studying the intestinal barrier, in which shear stress is critical for the differentiation of Caco-2 cells into enterocytes. The most commonly used in vitro gut model for intestinal barrier studies is based on trans-well cultures. Albeit useful, these culture systems lack physiological...
article 2020
document
Willems, N. (author), Yang, H.Y. (author), Langelaan, M.L.P. (author), Tellegen, A.R. (author), Grinwis, G.C.M. (author), Kranenburg, H.J.C. (author), Riemers, F.M. (author), Plomp, S.G.M. (author), Craenmehr, E.G.M. (author), Dhert, W.J.A. (author), Papen-Botterhuis, N.E. (author), Meij, B.P. (author), Creemers, L.B. (author), Tryfonidou, M.A. (author)
Introduction: Chronic low back pain due to intervertebral disc (IVD) degeneration is associated with increased levels of inflammatory mediators. Current medical treatment consists of oral anti-inflammatory drugs to alleviate pain. In this study, the efficacy and safety of a novel thermoreversible poly-N-isopropylacrylamide MgFe-layered double...
article 2015
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Burello, E. (author), Worth, A.P. (author)
article 2015
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Erinc, M. (author), Zhang, X. (author), Sillekens, W.H. (author), TNO Industrie en Techniek (author)
Magnesium and its alloys are light weight, biodegradable materials. They can be used as metal implants which maintain strength and integrity for the time of recovery, followed by natural dissolution in the body preventing the necessity of implant removal. In addition to the general biocompatibility and biodegradability requirements, these...
conference paper 2010
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TNO Industrie en Techniek (author), Ivan, M.G. (author), Vivet, F. (author), Meinders, E.R. (author)
Flexible microfluidic devices made of poly(dimethylsiloxane) (PDMS) were manufactured by soft lithography, and tested in detection of ionic species using optical absorption spectroscopy and electrical measurements. PDMS was chosen due to its flexibility and ease of surface modification by exposure to plasma and UV treatment, its transparency in...
conference paper 2010
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Li, Y. (author), de Vries, R. (author), Slaghek, T. (author), Timmermans, J. (author), Cohen Stuart, M.A. (author), Norde, W. (author), TNO Kwaliteit van Leven (author)
A novel biocompatible and biodegradable microgel system has been developed for controlled uptake and release of especially proteins. It contains TEMPO-oxidized potato starch polymers, which are chemically cross-linked by sodium trimetaphosphate (STMP). Physical chemical properties have been determined for microgels of different weight ratios of...
article 2009
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Pires, N.M.M. (author), van der Hoeven, B.L. (author), de Vries, M.R. (author), Havekes, L.M. (author), van Vlijmen, B.J. (author), Hennink, W.E. (author), Quax, P.H.A. (author), Jukema, J.W. (author), TNO Kwaliteit van Leven (author)
The introduction of drug-eluting stents (DES) to prevent in-stent restenosis is one of the major advances in interventional cardiology. Currently many types of DES are under evaluation for effectiveness and safety, a time-consuming and difficult procedure in humans. An animal model that allows rapid evaluation of the present and upcoming...
article 2005
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Zhu, Q. (author), de With, G. (author), Dortmans, L.J.M.G. (author), Feenstra, F. (author), TNO Industrie (author)
Near net-shape fabrication of hydroxyapatite (HA) glass composites has been attempted by infiltrating a glass into porous HA performs. Main efforts were put to develop glasses that are chemically compatible with HA at elevated temperatures. After extensive investigations in the phosphate and borosilicate systems, glasses of (50-55)SiO2-(20-25...
article 2004
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van der Bas, J.M.A. (author), Quax, P.H.A. (author), van den Berg, A.C. (author), Visser, M.J.T. (author), van der Linden, E. (author), van Bockel, J.H. (author), TNO Preventie en Gezondheid (author)
Objective: Endovascular aneurysm repair is an alternative treatment of abdominal aortic aneurysm. The procedure is less invasive, and morbidity and most probably mortality are reduced. However, some problems, such as endoleakage, are yet to be resolved. Endoleakage can occur after graft migration, as a result of insufficient fixation of the...
article 2004
document
Zhu, Q. (author), de With, G. (author), Dortmans, L.J.M.G. (author), Feenstra, F. (author)
The purpose of this study is to investigate the subcritical crack growth (SCG) behavior of alumina-glass dental composites. Alumina-glass composites were fabricated by infiltrating molten glass to porous alumina preforms. Rectangular bars of the composite were subject to dynamic loading in air, with stressing rates ranging from 0.01 MPa/s to 2...
article 2003
document
Gerritsen, M. (author), Jansen, J.A. (author), Kros, A. (author), Vriezema, D.M. (author), Sommerdijk, N.A.J.M. (author), Nolte, R.J.M. (author), Lutterman, J.A. (author), van Hövell, S.W.F.M. (author), van der Gaag, A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The objective of this investigation was to evaluate the influence of polymorphonuclear granulocytes on the performance of uncoated and cellulose acetate/Nafion® coated amperometric glucose sensors in vitro. The response of these sensors was also investigated in serum. Uncoated and coated sensors showed lower sensitivities to glucose, with a...
article 2001
document
Reichl, F.X. (author), Walther, U.I. (author), Durner, J. (author), Kehe, K. (author), Hickel, R. (author), Kunzelmann, K.H. (author), Spahl, W. (author), Hume, W.R. (author), Benschop, H.P. (author), Forth, W. (author)
Objective: The effect of dental composite components triethyleneglycoldimethacrylate (TEGDMA) and hydroxyethylmethacrylate (HEMA), as well as mercuric chloride (HgCl2) and methylmercury chloride (MeHgCl) was investigated on the release of lactatedehydrogenase (LDH) from alveolar epithelial lung cell lines in vitro. Methods: The confluent cell...
article 2001
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Teirlinck, C.J.P.M. (author), Bezemer, R.A. (author), Kollmann, C. (author), Lubbers, J. (author), Hoskins, P.R. (author), Fish, P. (author), Fredfeldt, K.-E. (author), Schaarschmidt, U.G. (author), TNO Preventie en Gezondheid (author)
Doppler test objects are used to characterise Doppler systems, both stand-alone systems and the Doppler part of so-called duplex scanners. The aim of the project partially presented here is the development and validation of an example of a Doppler test object fulfilling the requirements of the IEC 1685. The project has been carried out by nine...
article 1998
Searched for: subject%3A%22Biocompatibility%22
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