Searched for: subject:"Barriers"
(1 - 7 of 7)
document
van Wouwe, J.P. (author), Lanting, C.I. (author), van Dommelen, P. (author), Treffers, P.E. (author), van Buuren, S. (author), TNO Kwaliteit van Leven (author)
Aim: The aim of this study was to gain insight into contraception practised and related to breastfeeding duration. Methods: Mothers with infants up to 6 months received a questionnaire on infant feeding (breast or formula feeding) and contraception (hormonal or non-hormonal methods). Estimates of the time interval between resuming contraception...
article 2009
document
de Ruiter, M.C. (author), Alkemade, F.E. (author), de Gittenberger - Groot, A.C. (author), Poelmann, R.E. (author), Havekes, L.M. (author), van Dijk, K.W. (author), TNO Kwaliteit van Leven (author)
In this review, we briefly summarize the possible signals crossing the placental barrier and discuss the molecular mechanisms of epigenetic programming in the developing fetus leading to increased athero-susceptibility of the vessel wall. © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins.
article 2008
document
Dijkstra, S. (author), Kooij, G. (author), Verbeek, R. (author), van der Pol, S.M.A. (author), Amor, S. (author), Geisert Jr., E.E. (author), Dijkstra, C.D. (author), van Noort, J.M. (author), Vries, H.E.D. (author), TNO Kwaliteit van Leven (author)
Leukocyte infiltration is a key step in the development of demyelinating lesions in multiple sclerosis (MS), and molecules mediating leukocyte-endothelial interactions represent prime candidates for the development of therapeutic strategies. Here we studied the effects of blocking the integrin-associated tetraspanin CD81 in in vitro and in vivo...
article 2008
document
Buist, H.E. (author), de Heer, C. (author), van Burgsteden, J.A. (author), van de Sandt, J.J.M. (author), TNO Kwaliteit van Leven (author)
The in vitro dermal absorption kinetics of didecyldimethylammonium chloride (DDAC) was studied after single and multiple exposure. In addition, the influence of biocidal formulations on the absorption of DDAC was investigated. Following dermal exposure to DDAC in aqueous solution, less than 0.5% of the applied dose reached the receptor fluid...
article 2007
document
Buist, H.E. (author), van de Sandt, J.J.M. (author), van Burgsteden, J.A. (author), de Heer, C. (author), TNO Kwaliteit van Leven (author)
The dermal route of exposure is important in worker exposure to biocidal products. Many biocidal active substances which are used on a daily basis may decrease the barrier function of the skin to a larger extent than current risk assessment practice addresses, due to possible skin effects of repeated exposure. The influence of repeated and...
article 2005
document
Magos, L. (author), TNO BIBRA International Ltd, Woodmansterne Rd, Carshalton, Surrey SM5 4DS, United Kingdom Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
Chemicals/CAS: Biological Products; Ethylmercury Compounds; Food Additives; Pharmaceutical Preparations; Preservatives, Pharmaceutical; Thimerosal, 54-64-8
article 2001
document
Laman, J.D. (author), Maassen, C.B.M. (author), Schellekens, M.M. (author), Visser, L. (author), Kap, M. (author), de Jong, E. (author), van Puijenbroek, M. (author), van Stipdonk, M.J.B. (author), van Meurs, M. (author), Schwärzler, C. (author), Günthert, U. (author), TNO Preventie en Gezondheid (author)
Interactions between mononuclear cells are required for the formation of inflammatory infiltrates in the CNS and the activation of cellular effector functions provoking demyelination in MS. Membrane-expressed costimulatory molecules are crucial to such interactions. We therefore investigated whether two costimulatory molecules, CD40L (CD154,...
article 1998
Searched for: subject:"Barriers"
(1 - 7 of 7)