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Blom, W.M. (author), Westerhout, J. (author), Houben, G.F. (author)The need for region-specific food intake values to accurately estimate food allergen risk is underscored by the recent Ad Hoc Joint Food and Agriculture Organization/World Health Organization (FAO/WHO) Expert Consultation on Risk Assessment of Food Allergens (1). A recent study published by Sun et al. in China CDC Weekly 2022, titled A Chinese...article 2023
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van Hartingsveldt, W. (author), Meijerink, M. (author)New or modified proteins will play a key role in innovation of food products and in improving the sustainability of our food supply chain. New or modified protein-containing food products and ingredients may however lead to novel allergen risks. At TNO, we support you in the assessment of such risks based on our long-standing expertise and...other 2023
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van Hartingsveldt, W. (author), Houben, G.F. (author)Food products need to be safe! Allergen risk assessment is a key element of food safety assessment. Food allergic reactions as well as the risks thereof are a major burden to the food allergic consumer and their families as well as to the healthcare system.other 2023
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Schiefer, C. (author), Schellewald, V. (author), Heßling, S. (author), Hermanns-Truxius, I. (author), Desbrosses, K. (author), Douwes, M. (author), Draicchio, F. (author), Enquist, H. (author), Forsman, M. (author), Gupta, N. (author), Holtermann, A. (author), Konemann, R. (author), Lechner, N. (author), Loewis, P. (author), Mänttäri, S. (author), Mathiassen, S.E. (author), Pinder, A. (author), Schams P., (author), Schust, M. (author), Strebl, M. (author), Veiersted, K.B. (author), Weber, B. (author), Ellegast, R. (author)Technical measurements allow an objective assessment of MSD risk factors at work. There is a need for common standards regarding data collection and processing, as well as an exchange platform storing measurement data of occupational physical activity and workload for further analysis. Several research institutes started a feasibility study to...conference paper 2022
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Najjar, A. (author), Punt, A. (author), Wambaugh, J. (author), Paini, A. (author), Ellison, C. (author), Fragki, S. (author), Bianchi, E. (author), Zhang, F. (author), Westerhout, J. (author), Mueller, D. (author), Li, H. (author), Shi, Q. (author), Gant, T.W. (author), Botham, P. (author), Bars, R. (author), Piersma, A. (author), van Ravenzwaay, B. (author), Kramer, N.I. (author)With an increasing need to incorporate new approach methodologies (NAMs) in chemical risk assessment and the concomitant need to phase out animal testing, the interpretation of in vitro assay readouts for quantitative hazard characterisation becomes more important. Physiologically based kinetic (PBK) models, which simulate the fate of chemicals...article 2022
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Allaix, D.L. (author), bigaj-van Vliet, A. (author), Cerar, B. (author)Road and railway infrastructure networks form the backbone of European transportation systems, carrying more than 80% of passenger and 50% of goods transport in Europe. Bridges and tunnels which are critical elements of the transport infrastructure networks, have in many cases reached their design service life and keep ageing, with the...conference paper 2022
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de Wolff, M. (author), Klein Velderman, M. (author)Aim Conversation between Child Healthcare Professionals (CHPs) and parents and adolescents plays an important role in the quality and success of preventive health care delivery. However, there is no practice guideline on conversation. This study aimed to study 1) the needs of parents, adolescents, and Child Healthcare professionals regarding...conference paper 2022
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Sanchez, M.M. (author), Elfring, J. (author), Silvas, E. (author), van de Molengraft, R. (author)To operate safely, an automated vehicle (AV) must anticipate how the environment around it will evolve. For that purpose, it is important to know which prediction models are most appropriate for every situation. Currently, assessment of prediction models is often performed over a set of trajectories without distinction of the type of movement...conference paper 2022
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Eekhout, I. (author), van Buuren, S. (author), Verkerk, P. (author)There are many milestones available to measure child development in the first years of life. For less experienced professionals it is difficult to select the most relevant milestones to assess the developmental status of a child. Moreover, using the milestones separately makes is difficult to get a global impression of the developmental status....public lecture 2022
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Houben, G.F. (author), Blom, W.M. (author), Meijerink, M. (author)Food allergy has been recognized already in early history as a condition triggered in some individuals upon consumptions of specific foods. However, its recognition as an essential element to be addressed in food safety management is of much more recent date. As a consequence, risk assessment and risk management practices for food allergy are...bookPart 2022
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Rankouhi, T.R. (author), van Keulen, D. (author), Tempel, D. (author), Venhorst, J. (author)Background: Cardiovascular disease (CVD) is a leading cause of death worldwide. It is predicted that approximately 23.6 million people will die from CVDs annually by 2030. Therefore, there is a great need for an effective therapeutic approach to combat this disease. The European Cardiovascular Target Discovery (CarTarDis) consortium identified...article 2022
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Kamstra, R.J.M. (author), Boorsma, A. (author), Krone, T. (author), van Stokkum, R.M. (author), Eggink, H.M. (author), Peters, T. (author), Pasman, W.J. (author)Background: Study participants and patients often perceive (long) questionnaires as burdensome. In addition, paper-based questionnaires are prone to errors such as (unintentionally) skipping questions or filling in a wrong type of answer. Such errors can be prevented with the emergence of mobile questionnaire apps. Objective: This study aimed to...article 2022
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Mehta, R. (author), Golkaram, M. (author)There is a major push by governments and value chain partners to move towards circular options for difficult-to-recycle post-consumer products such as waste mattresses.[1] In the Netherlands alone ~1.5 million mattresses are discarded yearly, of which majority (>60%) is incinerated.[2] A sustainable solution to recycle waste mattresses is...conference paper 2022
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Blom, W.M. (author), Westerhout, J. (author), Baumert, J.L. (author), Meima, M.Y. (author), Turner, P.J. (author), Ebisawa, M. (author), Yanagida, N. (author), Remington, B.C. (author), Houben, G.F. (author)Access to Eliciting Doses (ED) for allergens enables advanced food allergen risk assessment. Previously, the full ED range for 14 allergenic foods, including milk, and recommendations for their use were provided (Houben et al., 2020). Additional food challenge studies with cow's milk-allergic patients added 247 data points to the original...article 2022
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Steubing, B. (author), de Koning, A. (author), Merciai, S. (author), Tukker, A. (author)Life cycle assessment (LCA) and environmentally extended input output analysis(EEIOA) are two widely used approaches to assess the environmental impacts of products and services with the aim of providing decision support. Here, we compare carbon footprint (CF) results for products and services in the ecoinvent 3.4 cut-off and the hybrid version...article 2022
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Semertzis, I. (author), Rajkumar, V.S. (author), Ştefanov, A. (author), Fransen, F. (author), Palensky, P. (author)Over the past decade, the number of cyber attack incidents targeting critical infrastructures such as the electrical power system has increased. To assess the risk of cyber attacks on the cyber-physical system, a holistic approach is needed that considers both system layers. However, the existing risk assessment methods are either qualitative in...conference paper 2022
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Pronk, A. (author), Loh, M. (author), Kuijpers, E. (author), Albin, M. (author), Selander, J. (author), Godderis, L. (author), Ghosh, M. (author), Vermeulen, R. (author), Peters, S. (author), Sivesind Mehlum, I. (author), Turner, M. (author), Schlunssen, V. (author), Goldberg, M. (author), Kogevinas, M. (author), Harding, B. (author), Solovieva, S. (author), Garani-Papadatos, T. (author), van Tongeren, M. (author), Stierum, R. (author)Exposures at work have a major impact on noncommunicable diseases (NCDs). Current risk reduction policies and strategies are informed by existing scientific evidence, which is limited due to the challenges of studying the complex relationship between exposure at work and outside work and health. We define the working life exposome as all...article 2022
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Terluin, B. (author), Eekhout, I. (author), Terwee, C.B. (author)Objectives: The anchor-based minimal important change (MIC), based on the receiver operating characteristic (ROC) analysis or predictive modeling, is biased by the proportion of improved patients. The adjusted MIC, published in 2017, adjusts the predictive MIC for this bias but does not take the reliability of the transition ratings (i.e., the...article 2022
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Dalla Longa, F. (author), Fragkos, P. (author), Pupo Nogueira, L. (author), van der Zwaan, B.C.C. (author)Supporting investments in energy efficiency is considered a robust strategy to achieve a successful transition to low-carbon energy systems in line with the Paris Agreement. Increased energy efficiency levels are expected to reduce the need for supply-side investments in controversial technologies, such as carbon dioxide capture and storage (CCS...article 2022
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Regeer, H. (author), van Empelen, P. (author), Bilo, H.J.G. (author), de Koning, E.J.P. (author), Huisman, S.D. (author)Objective. To examine the relationship between risk factors for low patient activation and change in patient activation, well-being, and health outcomes in people with type 2 diabetes mellitus (T2DM). Method. A longitudinal prospective study was conducted with measurements at baseline and 20-week follow-up among 603 people with T2DM...article 2022