Tissue damage and nutritional factors in experimental respiratory tract (co-)carcinogenesis

Cofactors involved in respiratory tract carcinogenesis were studied in Syrian golden hamster or in rats using benzo(a)pyrene as the carcinogenic agent. These factors included severe tissue tissue damage induced by electro-coagulation, glass fibers administered by intratracheal instillation, acetaldehyde as irritant vapor, food restriction, and...

Diet, faecal pH and colorectal cancer

We suggest that a lower faecal pH may be correlated with a lower mortality of large-bowel cancer and that faecal pH should always be considered in epidemiological studies on the role of diet in colon carcinogenesis.

Activation of plasminogen by tissue activator is increased specifically in the presence of certain soluble fibrin(ogen) fragments

Tissue activator-mediated plasminogen activation is potentiated both by fibrin and by some soluble fibrin(ogen) fragments. The potentiating effect of the different fragments decreases in the order fibrin monomer > D-dimer > Y > D EGTA > Dcate > X. Fibrinogen and the fragments Ecate, E EGTA and E fibrin have almost no effect. The existence of a...

Determination of the B2 vitamer flavin-adenine dinucleotide in whole blood by high-performance liquid chromatography with fluorometric detection

A reliable high-performance liquid chromatographic (HPLC) method is developed for the analysis of FAD in whole blood of humans. The method is able to separate FAD, FMN and Rb from each other and from interfering compounds. A reliable and sensitive detection of FAD has been obtained by selecting the optimal pH of the mobile phase and optimal...

Acetylcholine content and release in denervated or botulinum poisoned rat skeletal muscle

The acetylcholine (ACh) content and spontaneous and evoked release of ACh in rat extensor digitorum longus (EDL) muscles were determined by pyrolysis mass fragmentography. The determinations were made on muscles paralysed by local application of botulinum toxin (BoTx) type A, on unpoisoned muscles, surgically denervated or reinnervated muscles....

Methods for detection and determination of vegetable proteins in meat products

Soy protein is the vegetable protein that is most frequently used in meat products. Accordingly, detection and determination procedures have mainly been focused on soy proteins. Cereal proteins received far less attention analytically, let alone the less conventional vegetable proteins. Every method published has only a limited applicability,...

Context effects in short-term memory: Confirmatory evidence from recall of visually presented lists

Thirty-two subjects had tests of serial recall of visually presented nine-digit lists which were either presented in a single block of trials (constant context) or in between lists of much longer length (variable context). Other variables were vocalization-during-presentation versus silent memorization (within subject) and order of recall ...

Zitproblemen en de "vacuum-vormfixatie" (Sitting problems and the vacuum form fixation)

The merits of the 'vacuum form fixation' are discussed for the production of reliable body impressions of patients suffering from sitting problems. Impressions are taken with the patients seated in the desired posture. The first results are reported, obtained from 4 patients of different categories, fitted with individually moulded seats...

On threshold mechanisms for achromatic and chromatic vision

On the basis of measurements of the achromatic zone for red light in the fovea and for green light in the periphery, a discussion is given on the possible difference in threshold mechanisms for the achromatic (scotopic) and chromatic (photopic) retinal systems. A specific suggestion for this distinction is given that not directly refers to the...

Some effects of cognitive similarity on proactive and retriactive interference in short-term memory

An experiment is reported on the effects of cognitive similarity on proactive and retroactive interference (PI, RI) in short term memory. To avoid confounding between cognitive and acoustic similarity, the materials - i.e. words and digits - were matched with respect to vowel pattern. Effects of both PI and RI were found on recall of words,...

Cartilaginous focus at the base of the non-coronary semilunar valve of the aorta in rats of different ages

Cartilaginous tissue in the heart of rat has been described in literature by some as an ageing phenomenon, while others have observed it in young animals. Hearts of rats of different ages were studied for the occurence and localization of cartilaginous tissue. A cartilaginous focus has been regularly found in rats as young as 1 week old. This...

Simplification of sample loading in continuous automatic amino acid analysis

Recovery from the increase of the Stiles-Crawford effect after bleaching

THE Stiles–Crawford effect1,2, or the dependence of luminous efficiency on the eccentricity of the point of entry of the light in the pupil, is a function of the wavelength of the light. In Fig. 1 is given the inverse 1/ of the luminous efficiency as a function of wave-length at a distance of 3.5 mm from the point of maximum efficiency,...

Maximum oxygen uptake in healthy nonathletic males

Maximum oxygen uptake ( {Mathematical expression} max), maximum heart rate (MHR), blood lactic acid (LA) and pH were measured during bicycle ergometer exercise in 52 men, 22 to 60 years old, engaged in clerical and light manual work (prison personnel and prisoners in the Netherlands). {Mathematical expression} max decreases with, age, but less...