Searched for: subject:"Antidepressant%5C+agent"
(1 - 8 of 8)
document
Kruisdijk, F. (author), Deenik, J. (author), Yenback, D. (author), Tak, E.C. (author), van Harten, P. (author), Hopman-Rock, M. (author), Hendriksen, I. (author)
Sedentary behaviour and lack of physical activity threatens health. Research concerning these behaviours of inpatients with severe mental illness is limited but urgently needed to reveal prevalence and magnitude. In total, 184 inpatients (men n =108, women n =76, mean age 57,4, 20% first generation antipsychotics, 40% second generation...
article 2017
document
Mihaescu, R. (author), Detmar, S.B. (author), Cornel, M.C. (author), van der Flier, W.M. (author), Heutink, P. (author), Hol, E.M. (author), Rikkert, M.G.M.O. (author), van Duijn, C.M. (author), Janssens, A.C.J.W. (author), TNO Kwaliteit van leven (author)
Alzheimer's disease (AD) is the most prevalent form of dementia and the number of cases is expected to increase exponentially worldwide. Three highly penetrant genes (AβPP, PSEN1, and PSEN2) explain only a small number of AD cases with a Mendelian transmission pattern. Many genes have been analyzed for association with non-Mendelian AD, but the...
article 2010
document
Kroese, M.E.A.L. (author), Schulpen, G.J.C. (author), Sonneveld, H.M. (author), Vrijhoef, H.J.M. (author), TNO Kwaliteit van Leven (author)
Rationale: In this study, information was gathered from five disciplines on their usual management methods for fibromyalgia (FM) in order to asses whether treatment regimens have changed in the Netherlands during a period of 6 years. In addition, insight was gained into the therapeutic motives of the professionals. Method: A questionnaire was...
article 2008
document
Ploemen, J.P.H.T.M. (author), Kelder, J. (author), Hafmans, T. (author), van de Sandt, H. (author), van Burgsteden, J.A. (author), Salemink, P.J.M. (author), van Esch, E. (author), TNO Voeding (author)
Several cationic amphiphilic compounds are known to induce phospholipidosis, a condition primarily characterized by excessive accumulation of phospholipids in different cell types, giving the affected cells a finely foamy appearance. Excessive storage of lamellar membranous intralysosomal inclusion bodies is the hallmark for phospholipidosis on...
article 2004
document
Veraart, J.R. (author), Brinkman, U.A.Th. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Dialysis-solid-phase extraction (SPE) sample pretreatment is combined on-line with non-aqueous capillary electrophoresis for the determination of tricyclic antidepressants in urine and serum. After clean-up and enrichment, the water is removed from the sample matrix and the analytes are eluted from the cartridge by means of an organic solvent....
article 2001
document
TNO Preventie en Gezondheid (author), Janssen, H.A.M. (author), Borghouts, J.A.J. (author), Muris, J.W.M. (author), Metsemakers, J.F.M. (author), Koes, B.W. (author), Knottnerus, J.A. (author)
Background. While chronic non-specific abdominal complaints are common in general practice, data on patients' perspective and management of these complaints are lacking. Knowledge of these data is important for the development of guidelines for management and assessment of the burden of chronic non-specific abdominal complaints on society. Aim....
article 2000
document
Dahl, M.L. (author), Voortman, G. (author), Alm, C. (author), Elwin, C.E. (author), Delbressine, L. (author), Vos, R. (author), Bogaards, J.J.P. (author), Bertilsson, L. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
The novel antidepressant mirtazapine is a racemate with both noradrenergic and serotonergic potentiating effects. In vitro metabolism of racemic mirtazapine was studied in (a) microsomes from cells expressing different cytochrome P450 (CYP) enzymes and (b) human liver microsomes from 10 subjects and compared with the rate of metabolism of 4...
article 1997
document
Wieling, J. (author), Dijkstra, H. (author), Mensink, C.K. (author), Jonkman, J.H.G. (author), Coenegracht, P.M.J. (author), Duineveld, C.A.A. (author), Doornbos, D.A. (author), Instituut voor Milieuwetenschappen TNO (author)
A general systematic approach is described for the chemometric modelling of liquid-liquid extraction data of drugs from biological fluids. Extraction solvents were selected from Snyder's solvent selectivity triangle; methyl tert.-butyl ether, methylene chloride and chloroform. The composition of a mixture of the three extraction solvents was...
article 1993
Searched for: subject:"Antidepressant%5C+agent"
(1 - 8 of 8)