Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models

Salsalate activates brown adipose tissue in mice

Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?

The probiotic mixture VSL#3 has differential effects on intestinal immune parameters in healthy female BALB/c and C57BL/6 mice

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

A First Exploration of Health Impact Assessment of Chemical Exposure: Assigning Weights to Subclinical Effects Based on Animal Studies

Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice

Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet

Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma

Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil

Anacetrapib reduces (V)LDL-cholesterol by inhibition of CETP activity and reduction of plasma PCSK9

Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome

Evaluation of an alternative in vitro test battery for detecting reproductive toxicants in a grouping context

Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: Alternative approaches

Drugs that reverse disease transcriptomic signatures are more effective in a mouse model of dyslipidemia

State of the art on alternative methods to animal testing from an industrial point of view: Ready for regulation?

The minipig as an alternative non-rodent model for immunogenicity testing using the TNFα blockers adalimumab and infliximab

High thresholds for avoidance of sonar by free-ranging long-finned pilot whales (Globicephala melas)

PET imaging of disease progression and treatment effects in the experimental autoimmune encephalomyelitis rat model

Differential modulation by Akkermansia muciniphila and faecalibacterium prausnitzii of host peripheral lipid metabolism and histone acetylation in mouse gut organoids