No effects of PCSK9-inhibitor treatment on spatial learning, locomotor activity, and novel object recognition in mice

Microphysiological Systems to Recapitulate the Gut–Kidney Axis

The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testing

Overview of in Vivo and Ex Vivo Endpoints in Murine Food Allergy Models: Suitable for Evaluation of the Sensitizing Capacity of Novel Proteins?

A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology

Mechanistic Similarities between 3D Human Bronchial Epithelium and Mice Lung, Exposed to Copper Oxide Nanoparticles, Support Non-Animal Methods for Hazard Assessment

High-fat feeding primes the mouse knee joint to develop osteoarthritis and pathologic infrapatellar fat pad changes after surgically induced injury

Effects of Inhibition or Deletion of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) on Intracerebral Hemorrhage Volumes in Mice

The mechanistic overview of SARS-CoV-2 using angiotensin-converting enzyme 2 to enter the cell for replication Possible treatment options related to the renin-angiotensin system

A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals

Predicting acoustic dose associated with marine mammal behavioural responses to sound as detected with fixed acoustic recorders and satellite tags

Successional Dynamics in the Gut Microbiome Determine the Success of Clostridium difficile Infection in Adult Pig Models

Allergenic and novel food proteins State of the art and challenges in the allergenicity assessment

Guidelines for using animal models in blast injury research

Longitudinal characterization of diet-induced genetic murine models of non-alcoholic steatohepatitis with metabolic histological and transcriptomic hallmarks of human patients

Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study

Metabolic dysregulation accelerates injury-induced joint degeneration, driven by local inflammation; an in vivo rat study

LPS-Induced Systemic Inflammation Does Not Alter Atherosclerotic Plaque Area or Inflammation in APOE3*LEIDEN Mice in the Early Phase Up to 15 Days

Reversal of visceral hypersensitivity in rat by Menthacarin®, a proprietary combination of essential oils from peppermint and caraway, coincides with mycobiome modulation

Evaluating in vitro-in vivo extrapolation of toxicokinetics