Searched for: subject%3A%22Analysis%255C%2Bof%255C%2BVariance%22
(21 - 40 of 109)
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Rad, M. (author), Kluft, C. (author), Ménard, J. (author), Burggraaf, J. (author), de Kam, M.L. (author), Meijer, P. (author), Sivin, I. (author), Sitruk-Ware, R.L. (author), TNO Kwaliteit van Leven (author)Objective: This study aimed to compare the effects on hemostasis variables of a contraceptive vaginal ring with those of an oral contraceptive. Study design: Twenty-three and 22 healthy premenopausal women were randomized to the contraceptive vaginal ring (150 μg Nestorone and 15 μg ethinyl estradiol) or Stediril 30 during 3 cycles. Analysis of...article 2006
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Proper, K.I. (author), van den Heuvel, S.G. (author), de Vroome, E.M. (author), Hildebrandt, V.H. (author), van der Beek, A.J. (author), TNO Kwaliteit van Leven (author)Objective: To investigate the dose-response relation between moderate and vigorous physical activity and sick leave in a working population. Methods: Data were used from three large Dutch databases: two continuous, cross sectional surveys among a representative sample of the Dutch population and one prospective cohort study. A distinction was...article 2006
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Valstar, D.L. (author), Schijf, M.A. (author), Nijkamp, F.P. (author), Storm, G. (author), Arts, J.H.E. (author), Kuper, C.F. (author), Bloksma, N. (author), Henricks, P.A.J. (author), TNO Kwaliteit van Leven (author)Occupational exposure to low molecular weight chemicals, like trimellitic anhydride (TMA), can result in occupational asthma. Alveolar macrophages (AMs) are among the first cells to encounter inhaled compounds. These cells can produce many different mediators that have a putative role in asthma. In this study, we examined the role of AMs in lung...article 2006
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Proper, K.I. (author), Hildebrandt, V.H. (author), TNO Kwaliteit van Leven (author)Objective.: This study describes the total physical activity and the contribution of work to total physical activity among Dutch workers. The study was conducted in the Netherlands in the years 2000-2002. Methods.: 2,417 respondents of a cross-sectional survey representing the Dutch adult working population were included. Physical activity was...article 2006
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Chang, W.T. (author), Thissen, U. (author), Ehlert, K.A. (author), Koek, M.M. (author), Jellema, R.H. (author), Hankemeier, T. (author), van der Greef, J. (author), Wang, M. (author), TNO Kwaliteit van Leven TNO Voeding (author)Metabolite profiling in combination with multivariate statistics is a sophisticated method for quality assessment of natural products. For the development of a quality control strategy in Traditional Chinese Medicine (TCM), we have measured the metabolite fingerprints of Rehmannia glutinosa by GC-MS. Plants were grown under different climate and...article 2006
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Bildt, M.M. (author), Snoek-van Beurden, A.M.P. (author), de Groot, J. (author), van El, B. (author), Kuijpers-Jagtman, A.M. (author), van den Hoff, J.W. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Background and Objective: The purpose of this study was to investigate the effects of chemically modified tetracyclines (CMTs) on the production of gelatinases [matrix metalloproteinase (MMP)-2 and -9] by human periodontal ligament (PDL) cells, and on the activity of recombinant gelatinases. Material and Methods: Human PDL cells were cultured...article 2006
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TNO Kwaliteit van Leven (author), Sluijter, J.P.G. (author), Pulskens, W.P.C. (author), Schoneveld, A.H. (author), Velema, E. (author), Strijder, C.F. (author), Moll, F. (author), de Vries, J.P. (author), Verheijen, J. (author), Hanemaaijer, R. (author), de Kleijn, D.P.V. (author), Pasterkamp, G. (author)Background and Purpose - We studied matrix metalloproteinases (MMP) 2, 8, and 9 and extracellular matrix metalloproteinase inducer (EMMPRIN) levels in relation to carotid atherosclerotic plaque characteristics. Methods - Carotid atherosclerotic plaques (n=150) were stained and analyzed for the presence of collagen, smooth muscle cell (SMC), and...article 2006
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van den Heuvel, S.G. (author), Boshuizen, H.C. (author), Hildebrandt, V.H. (author), Blatter, B.M. (author), Ariëns, G.A. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)OBJECTIVES: To determine the effects of sporting activity on absenteeism in a working population. METHODS: Data were used from a prospective cohort study in a working population with a follow up period of 3 years and were collected with yearly questionnaires or collected from company records. Complete data on absenteeism, sporting activity, and...article 2005
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van den Hauwe, O. (author), Campbell, K. (author), Crooks, S.R.H. (author), Schilt, R. (author), van Peteghem, C.H. (author), TNO Kwaliteit van Leven (author)Within the framework of a European Union (EU) research project entitled "Food Safety Screening: Synthetic Glucocorticoids (QLK1-1999-00122)," an international interlaboratory ring test was organized to compare and evaluate different liquid chromatography/mass spectrometry (LC/MS) confirmatory methods that are applied in European monitoring...article 2005
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Smilde, A.K. (author), Jansen, J.J. (author), Hoefsloot, H.C.J. (author), Lamers, R.J.A.N. (author), van der Greef, J. (author), Timmerman, M.E. (author), TNO Kwaliteit van Leven (author)Motivation: Datasets resulting from metabolomics or metabolic profiling experiments are becoming increasingly complex. Such datasets may contain underlying factors, such as time (time-resolved or longitudinal measurements), doses or combinations thereof. Currently used biostatistics methods do not take the structure of such complex datasets into...article 2005
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Lin, Y.L. (author), Brama, P.A.J. (author), Kiers, G.H. (author), de Groot, J. (author), van Weeren, P.R. (author), TNO Preventie en Gezondheid (author)Objective - To quantify and compare biochemical characteristics of the extracellular matrix (ECM) of specimens harvested from tensional and compressive regions of the superficial digital flexor tendon (SDFT) of horses in age classes that include neonates to mature horses. Sample population - Tendon specimens were collected on postmortem...article 2005
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Markus, C.R. (author), Jonkman, L.M. (author), Lammers, J.H.C.M. (author), Deutz, N.E.P. (author), Messer, M.H. (author), Rigtering, N. (author), TNO Kwaliteit van Leven TNO Voeding (author)Background: Brain serotonin function is thought to promote sleep regulation and cognitive processes, whereas sleep abnormalities and subsequent behavioral decline are often attributed to deficient brain serotonin activity. Brain uptake of the serotonin precursor tryptophan is dependent on nutrients that influence the availability of tryptophan...article 2005
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van Rhenen, W. (author), Blonk, R.W.B. (author), van der Klink, J.J. (author), van Dijk, F.J. (author), Schaufeli, W.B. (author), TNO Kwaliteit van Leven (author)Objectives: To investigate the short-term and long-term effectiveness of two, brief, preventive, work stress management programmes. One programme was a cognition-focused programme, the other was a newly developed intervention in which physical exercise and relaxation were combined. It was hypothesised that the newly developed intervention would...article 2005
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Schraagen, J.M.C. (author), van Dongen, C.J.G. (author), TNO Defensie en Veiligheid (author)Good memorability of licence plates is important in those cases where licence plates are viewed for a brief period of time and the information is essential for police investigations. The purpose of the current study was to design a new Dutch licence plate that could be remembered well. A memory experiment was conducted, in which 16 different...article 2005
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Dhonukshe-Rutten, R.A.M. (author), van Dusseldorp, M. (author), Schneede, J. (author), de Groot, L.C.P.G.M. (author), van Staveren, W.A. (author), TNO Kwaliteit van Leven (author)Background: Cobalamin deficiency is prevalent in vegetarians and has been associated with increased risk of osteoporosis. Aim of the study: To examine the association between cobalamin status and bone mineral density in adolescents formerly fed a macrobiotic diet and in their counterparts. Methods: In this cross-sectional study bone mineral...article 2005
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Blom, W.A.M. (author), Stafleu, A. (author), de Graaf, C. (author), Kok, F.J. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)Background: Ghrelin plays an important role in the regulation of food intake. Little is known about how ghrelin concentrations are modified by dietary factors. Objective: We examined the effects of both amount and type of carbohydrate on ghrelin concentrations and all correlations among the variables ghrelin, glucose, insulin, leptin, and all 4...article 2005
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Ullmann, U. (author), Haller, J. (author), Bakker, G.C.M. (author), Brink, E.J. (author), Weber, P. (author), TNO Kwaliteit van Leven (author)A number of studies have shown that tea catechins can inhibit intestinal iron absorption, mostly iron in the nonhaem form. This randomized, double-blind, placebo-controlled, 3-periods cross-over study examined the degree of inhibition of nonhaem iron absorption by pure crystalline epigallocatechin gallate (EGCG). The study was designed to show...article 2005
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Gijsbers, J.H.J. (author), Tielemans, E. (author), Brouwer, D.H. (author), van Hemmen, J.J. (author), TNO Voeding (author)Introduction: Limited quantitative information is available on dermal exposure to chemicals during various industrial activities. Therefore, within the scope of the EU-funded RISKOFDERM project, potential dermal exposure was measured during three different tasks: filling, loading and brushing. DEGBE (2-(2-butoxyethoxy)ethanol) was used as a ...article 2004
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Delaney, B. (author), de Vogel, N. (author), Krul, C.A.M. (author), TNO Voeding (author)Chemicals / CAS: corn oil, 8001-30-7; mitomycin C, 50-07-7, 74349-48-7; Glucans; Mutagensarticle 2004
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Kromhout, H. (author), Fransman, W. (author), Vermeulen, R. (author), Roff, M. (author), van Hemmen, J.J. (author), TNO Voeding (author)Introduction: The RISKOFDERM project collected task-based estimates of potential dermal exposure from a wide range of industries and services from around Europe. A formal statistical analysis was carried out to explore the main components of variability in dermal exposure levels. The central research question was to what extent dermal exposure...article 2004
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