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Centraal Instituut voor Voedingsonderzoek TNO (author), Speek, A.J. (author), Schrijver, J. (author), Schreurs, W.H.P. (author)Chemicals/CAS: menadione sodium bisulfite, 130-37-0; menadione, 58-27-5; 2-methyl-1,4-dihydronaphthalene, 2717-43-3; Naphthalenes; Vitamin K 3, 58-27-5; Vitamin K, 12001-79-5.article 1984
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van der Greef, J. (author), Leegwater, D.C. (author)A technique for the detection of biotransformation products of xenobiotics in crude urine extracts by field desorption mass spectrometric profile analysis is described. The method comprises determination of peak profiles of a series of blank and test samples using low resolution field desorption mass spectrometry, comparison of averaged peak...article 1983
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Bemelmans, J.M.H. (author), den Braber, H.J.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Marinated herring from the Baltic Sea was found to have an offensive odor and taste described as iodine-like and phenolic. Fat isolated from herring was found to contain this taint. The volatiles were isolated from the fat, using a molecular distillation and were subsequently fractionated by gas chromatography. A fraction containing the taint...conference paper 1983
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Speek, A.J. (author), Odink, J. (author), Schrijver, J. (author), Schreurs, W.H.P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)A reliable high-performance liquid chromatographic method is presented for the determination of the urinary free catecholamines noradrenaline, adrenaline and dopamine. Urine is purified on a column of immobilized boric acid. Catecholamines are separated by ion-pair reversed phase high-performance liquid chromatography and detected...article 1983
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Appelman, L.M. (author), ten Berge, W.F. (author), Reuzel, P.G.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The acute inhalation toxicity of ammonia was examined in rats using various exposure concentrations and exposure periods. Groups of male and female rats were exposed to dynamic atmospheres containing different concentrations of ammonia for 10, 20, 40 or 60 min. The aim of the study was to establish the relationship between exposure concentration...article 1982
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- Prins Maurits Laboratorium TNO (author), van Havere, W. (author), Lenstra, A.T.H. (author), Geise, H.J. (author), van den Berg, G.R. (author), Benschop, H.P. (author) article 1982
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- Prins Maurits Laboratorium TNO (author), van Havere, W. (author), Lenstra, A.T.H. (author), Geise, H.J. (author), van den Berg, G.R. (author), Benschop, H.P. (author) article 1982
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- Prins Maurits Laboratorium TNO (author), van Havere, W. (author), Lenstra, A.T.H. (author), Geise, H.J. (author), van den Berg, G.R. (author), Benschop, H.P. (author) article 1982
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Centraal Instituut voor Voedingsonderzoek TNO (author), van Dokkum, W. (author), de Vos, R.H. (author), Cloughley, F.A. (author), Hulshof, K.F.A.M. (author), Dukel, F. (author), Wijsman, J.A. (author)During a period of 2 years, every 2 months 126 different food items forming a 'market basket' were purchased, prepared and divided into twelve food commodity groups. The 'market basket' was based on a study of the dietary pattern of 16- to 18-year-old male adolescents. In the (homogenized) food group various additives and components of...article 1982
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- Barendregt, R.B. (author) doctoral thesis 1981
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Brasser, L.J. (author)Starting in the winter 1964-1965, the TNO Research Institute for Environmental Hygiene has determined the PAH-concentrations of the atmosphere at several locations in The Netherlands. Long series of data are available for several stations. The trend in the concentrations is spectacular: the concentrations have fallen from relatively high values...other 1981
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Benschop, H.P. (author), van den Berg, G.R. (author), van Hooidonk, C. (author), de Jong, L.P.A. (author), Kientz, C.E. (author), Berends, F. (author), Kepner, L.A. (author), Meeter, E. (author), Visser, R.P.L.S. (author), Medisch Biologisch Laboratorium TNO (author)Three new nonquaternary oximes have been evaluated with respect to their antidotal activities against organophosphate poisoning. The oximes 1,2,3-thiadiazole-5-carboxaldoxime (1, pKa = 7.6), 2-methyl-1,3,4-thiadiazole-5-carboxaldoxime (2, pKa = 8.4), and 3-methyl-1,2,4-thiadiazole-5-carboxaldoxime (3, pKa = 7.0) were prepared in yields of 56, 24...article 1979
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Lindqvist, F. (author), Instituut voor Milieuhygiëne en Gezondheidstechniek TNO (author)A continuous method for the measurement of SO2 in ambient air at trace levels is described. The principle of detection is based on the anodic oxidation of SO2 in a galvanic cell. A differential measuring technique with a cell with two anodes and one cathode is used; background and noise current are low and stable. A feature of the measuring...article 1978
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Haagsma, N. (author), Slump, P. (author), Gortemaker, B. (author), Schreuder, R. (author), Centraal instituut voor voedingsonderzoek TNO (author)A comparison is made between lysinoalanine (LAL) determinations both with an automatic amino acid analyzer (AAA) and with thin layer chromatography-densitometry (TLC) in different types of food and food ingredients, taken from the Dutch market. Generally there is a reasonable agreement between the LAL content obtained by both methods. However,...article 1978
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- Radiologische dienst TNO (author), Julius, H.W. (author) conference paper 1978
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Organisch Chemisch Instituut TNO (author), Meinema, H.A. (author), Burger-Wiersma, T. (author), Versluis-de Haan, G. (author), Gevers Ch., E. (author)A sensitive, reproducible, and interference-free method is presented for simultaneous determination of tri-, di- and monobutyltin species present in aqueous systems at tin concentrations of 0.01 - 5.0 ppm. The butyltin species are concentrated from HBr acidified aqueous solutions into an organic solvent by solvent extraction in the presence of a...article 1978
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Olsman, W.J. (author), van Leeuwen, C.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)An improved procedure for the determination of protein-bound nitrite (PBN) in meat products, based on Mirna's method, is described. The results obtained with this modification are significantly higher, and have a lower variation coefficient, than those provided by the old procedure. This is demonstrated by comparison of the analytical results....article 1977
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Haaijman, J.J. (author), Brinkhof, J. (author), Instituut voor Experimentele Gerontologie TNO (author), IVEG (author)The IgG fractions of rabbit antisera specific for the Fc part of mouse IgA, IgM, and the four subclasses of IgG (1, 2a, 2b, and 3) were coupled covalently to Sepharose beads by the cyanogen bromide method. The beads were then incubated with different dilutions of mouse serum. The mouse immunoglobulins (Ig) binding to the beads were demonstrated...article 1977
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Wolthuis, O.L. (author), Clason-van der Wiel, H.J. (author), Visser, R.P.L.S. (author), Medisch Biologisch Laboratorium TNO Chemisch Laboratorium TNO (author)Atropinised anaesthetised rats were injected i.v. with 4, 6 or 8 x LD50 of the organophosphorous anticholinesterase soman. Subsequent treatment with one dose of HS 6 (100 mg/kg, i.v.) delayed respiratory failure by 1 h or more; a further postponement was obtained when an additional HS 6 infusion was given. At the same infusion rate, HS 6 blood...article 1976
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de Vos, R.H. (author), ten Noever de Brauw, M.C. (author), Olthof, P.D.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Pentachloronitrobenzene (PCNB, also known as Quintozene, Terraclor) is used as a soil fungicide in greenhouses, mainly for the control of Rhizoctonia and Botrytis in lettuce. During an examination (by gas liquid chromatography) of a number of soil samples from greenhouses, not only a PCNB peak was found in the chromatograms, but also several...article 1974