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Andersen, Z.J. (author), Pedersen, M. (author), Weinmayr, G. (author), Stafoggia, M. (author), Galassi, C. (author), Jørgensen, J.T. (author), Sommar, J.N. (author), Forsberg, B. (author), Olsson, D. (author), Oftedal, B. (author), Aasvang, G.M. (author), Schwarze, P. (author), Pyko, A. (author), Pershagen, G. (author), Korek, M. (author), Faire, U.D. (author), Östenson, C.G. (author), Fratiglioni, L. (author), Eriksen, K.T. (author), Poulsen, A.H. (author), Tjønneland, A. (author), Braüner, E.V. (author), Peeters, P.H. (author), Bueno de Mesquita, B. (author), Jaensch, A. (author), Nagel, G. (author), Lang, A. (author), Wang, M. (author), Tsai, M.Y. (author), Grioni, S. (author), Marcon, A. (author), Krogh, V. (author), Ricceri, F. (author), Sacerdote, C. (author), Migliore, E. (author), Vermeulen, R. (author), Sokhi, R. (author), Keuken, M. (author), de Hoogh, K. (author), Beelen, R. (author), Vineis, P. (author), Cesaroni, G. (author), Brunekreef, B. (author), Hoek, G. (author), Raaschou-Nielsen, O. (author)Background. Epidemiological evidence on the association between ambient air pollution and brain tumor risk is sparse and inconsistent. Methods. In 12 cohorts from 6 European countries, individual estimates of annual mean air pollution levels at the baseline residence were estimated by standardized land-use regression models developed within the...article 2018
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de Kluizenaar, Y. (author), Kuijpers, E. (author), Eekhout, I. (author), Voogt, M. (author), Vermeulen, R.C.H. (author), Hoek, G. (author), Sterkenburg, R.P. (author), Pierik, F.H. (author), Duyzer, J.H. (author), Meijer, E.W. (author), Pronk, A. (author)Particulate matter exposure may cause adverse health effects. Although ultrafine particulate matter (UFP) is hypothesised to be particularly health relevant, the number of studies into personal UFP exposure is limited. Aim To increase insight where and when most UFP exposure occurs, in terms of exposure levels and peaks in microenvironments,...article 2017
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Bekker, C. (author), Fransman, W. (author), Boessen, R. (author), Oerlemans, A. (author), Ottenbros, I.B. (author), Vermeulen, R. (author)Background: Nano-specific inhalation exposure models could potentially be effective tools to assess and control worker exposure to nano-objects, and their aggregates and agglomerates (NOAA). However, due to the lack of reliable and consistent collected NOAA exposure data, the scientific basis for validation of the existing NOAA exposure models...article 2017
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Deziel, N.C. (author), Nuckols, J.R. (author), Jones, R.R. (author), Graubard, B.I. (author), de Roos, A.J. (author), Pronk, A. (author), Gourley, C. (author), Colt, J.S. (author), Ward, M.H. (author)Proximity to facilities emitting polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/F) has been associated with increased risk of non-Hodgkin lymphoma (NHL). There is limited information about whether proximity to industrial sources leads to indoor PCDD/F contamination of homes. We measured carpet dust concentrations (pg/g...article 2017
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Ghosh, M (author), Oner, D. (author), Poels, K. (author), Tabish, A.M. (author), Vlaanderen, J. (author), Pronk, A. (author), Kuijpers, E. (author), Lan, Q. (author), Vermeulen, R. (author), Bekaert, B. (author), Hoet, P.H.M. (author), Godderis, L. (author)This study was designed to assess the epigenetic alterations in blood cells, induced by occupational exposure to multi-wall carbon nanotubes (MWCNT). The study population comprised of MWCNT-exposed workers (n=24) and unexposed controls (n=43) from the same workplace. We measured global DNA methylation/hydroxymethylation levels on the 5th...article 2017
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Zarcone, M.C. (author), van Schadewijk, A. (author), Duistermaat, E. (author), Hiemstra, P.S. (author), Kooter, I.M. (author)Background: Exacerbations constitute a major cause of morbidity and mortality in patients suffering from chronic obstructive pulmonary disease (COPD). Both bacterial infections, such as those with non-typeable Haemophilus influenzae (NTHi), and exposures to diesel engine emissions are known to contribute to exacerbations in COPD patients....article 2017
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Sabel, C.E. (author), Hiscock, R. (author), Asikainen, A. (author), Bi, J. (author), Depledge, M. (author), Van Den Elshout, S. (author), Friedrich, R. (author), Huang, G. (author), Hurley, F. (author), Jantunen, M. (author), Karakitsios, S.P. (author), Keuken, M. (author), Kingham, S. (author), Kontoroupis, P. (author), Kuenzli, N. (author), Liu, M. (author), Martuzzi, M. (author), Morton, K. (author), Mudu, P. (author), Niittynen, M. (author), Perez, L. (author), Sarigiannis, D. (author), Stahl-Timmins, W. (author), Tobollik, M. (author), Tuomisto, J. (author), Willers, S. (author)Background: Climate change is a global threat to health and wellbeing. Here we provide findings of an international research project investigating the health and wellbeing impacts of policies to reduce greenhouse gas emissions in urban environments. Methods: Five European and two Chinese city authorities and partner academic organisations formed...article 2016
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Hendriks, C. (author), Kranenburg, R. (author), Kuenen, J.J.P. (author), van den Bril, B. (author), Verguts, V. (author), Schaap, M. (author)Accurate modelling of mitigation measures for nitrogen deposition and secondary inorganic aerosol (SIA) episodes requires a detailed representation of emission patterns from agriculture. In this study the meteorological influence on the temporal variability of ammonia emissions from livestock housing and application of manure and fertilizer are...article 2016
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Pedersen, M. (author), Gehring, U. (author), Beelen, R. (author), Wang, M. (author), Giorgis-Allemand, L. (author), Andersen, A.M.N. (author), Basagaña, X. (author), Bernard, C. (author), Cirach, M. (author), Forastiere, F. (author), de Hoogh, K. (author), Gražuleviĉvienė, R. (author), Gruzieva, O. (author), Hoek, G. (author), Jedynska, A. (author), Klümper, C. (author), Kooter, I.M. (author), Krämer, U. (author), Kukkonen, J. (author), Porta, D. (author), Postma, D.S. (author), Raaschou-Nielsen, O. (author), van Rossem, L. (author), Sunyer, J. (author), Sørensen, M. (author), Tsai, M.Y. (author), Vrijkotte, T.G.M. (author), Wilhelm, M. (author), Nieuwenhuijsen, M.J. (author), Pershagen, G. (author), Brunekreef, B. (author), Kogevinas, M. (author), Slama, R. (author)Background: The health effects of suspended particulate matter (PM) may depend on its chemical composition. Associations between maternal exposure to chemical constituents of PM and newborn’s size have been little examined. Objective: We aimed to investigate the associations of exposure to elemental constituents of PM with term low birth weight ...article 2016
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Tobollik, M. (author), Keuken, M. (author), Sabel, C. (author), Cowie, H. (author), Tuomisto, J. (author), Sarigiannis, D. (author), Künzli, N. (author), Perez, L. (author), Mudu, P. (author)Background: Green house gas (GHG) mitigation policies can be evaluated by showing their co-benefits to health. Method: Health Impact Assessment (HIA) was used to quantify co-benefits of GHG mitigation policies in Rotterdam. The effects of two separate interventions (10% reduction of private vehicle kilometers and a share of 50% electric-powered...article 2016
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van Holsteijn, R.C.A. (author), Li, W.L. (author), Valk, H.J.J. (author), Kornaat, W. (author)MONICAIR - MONItoring & Control of Air quality in Individual Rooms - is a pre-competitive field research project of a broad consortium of Dutch ventilation unit manufacturers and research institutes, supported by the Dutch government. The first aim of the project is to investigate and compare the indoor air quality (IAQ) performance and energy...article 2016
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Willers, S.M. (author), Jonker, M.F. (author), Klok, L. (author), Keuken, M.P. (author), Odink, J. (author), van den Elshout, S. (author), Sabel, C.E. (author), Mackenbach, J.P. (author), Burdorf, A. (author)Background: Elevated temperature and air pollution have been associated with increased mortality. Exposure to heat and air pollution, as well as the density of vulnerable groups varies within cities. The objective was to investigate the extent of neighbourhood differences in mortality risk due to heat and air pollution in a city with a temperate...article 2016
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Duyzer, J. (author), van den Hout, D. (author), Zandveld, P. (author), van Ratingen, S. (author)The suitability of European networks to check compliance with air quality standards and to assess exposure of the population was investigated. An air quality model (URBIS) was applied to estimate and compare the spatial distribution of the concentration of nitrogen dioxide (NO2) in ambient air in four large cities. The concentrations calculated...article 2015
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Jedynska, A. (author), Hoek, G. (author), Wang, M. (author), Eeftens, M. (author), Cyrys, J. (author), Beelen, R. (author), Cirach, M. (author), De Nazelle, A. (author), Keuken, M. (author), Visschedijk, A. (author), Nystad, W. (author), Akhlaghi, H.M. (author), Meliefste, K. (author), Nieuwenhuijsen, M. (author), de Hoogh, K. (author), Brunekreef, B. (author), Kooter, I.M. (author)Relatively little is known about long term effects of wood smoke on population health. A wood combustion marker - levoglucosan - was measured using a standardized sampling and measurement method in four European study areas (Oslo, The Netherlands, Munich/Augsburg, Catalonia) to assess within and between study area spatial variation. Levoglucosan...article 2015
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Tsai, M.Y. (author), Hoek, G. (author), Eeftens, M. (author), de Hoogh, K. (author), Beelen, R. (author), Beregszászi, T. (author), Cesaroni, G. (author), Cirach, M. (author), Cyrys, J. (author), de Nazelle, A. (author), de Vocht, F. (author), Ducret-Stich, R. (author), Eriksen, K. (author), Galassi, C. (author), Gražuleviciene, R. (author), Gražulevicius, T. (author), Grivas, G. (author), Gryparis, A. (author), Heinrich, J. (author), Hoffmann, B. (author), Iakovides, M. (author), Keuken, M. (author), Krämer, U. (author), Künzli, N. (author), Lanki, T. (author), Madsen, C. (author), Meliefste, K. (author), Merritt, A.S. (author), Mölter, A. (author), Mosler, G. (author), Nieuwenhuijsen, M.J. (author), Pershagen, G. (author), Phuleria, H. (author), Quass, U. (author), Ranzi, A. (author), Schaffner, E. (author), Sokhi, R. (author), Stempfelet, M. (author), Stephanou, E. (author), Sugiri, D. (author), Taimisto, P. (author), Tewis, M. (author), Udvardy, O. (author), Wang, M. (author), Brunekreef, B. (author)An increasing number of epidemiological studies suggest that adverse health effects of air pollution may be related to particulate matter (PM) composition, particularly trace metals. However, we lack comprehensive data on the spatial distribution of these elements.We measured PM<inf>2.5</inf> and PM<inf>10</inf> in twenty study areas across...article 2015
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van Laarhoven, K.A. (author), Huinink, H.P. (author), Segers, F.J.J. (author), Dijksterhuis, J. (author), Adan, O.C.G. (author)To prevent indoor fungal growth, understanding the moisture relations of fungi is a key element. Indoor moisture is quantified by the relative humidity (RH). RH controls the water activity of the indoor materials that fungi grow on, a well-studied parameter known to limit fungal growth. RH, however, also controls the amount of water present in...article 2015
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Walser, T. (author), Meyer, D. (author), Fransman, W. (author), Buist, H. (author), Kuijpers, E. (author), Brouwer, D. (author)Life-Cycle Assessment (LCA) is a well-established method to evaluate impacts of chemicals on the environment and human health along the lifespan of products. However, the increasingly produced and applied nanomaterials (defined as one dimensionarticle 2015
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Karanasiou, A. (author), Amato, F. (author), Moreno, T. (author), Lumbreras, J. (author), Borge, R. (author), Linares, C. (author), Boldo, E. (author), Alastuey, A. (author), Querol, X. (author)Although previous studies report on the effect of street washing on ambient particulate matter levels, there is a lack of studies investigating the results of street washing on the emission strength of road dust. A sampling campaign was conducted in Madrid urban area during July 2009 where road dust samples were collected in two sites, namely...article 2014
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Keuken, M.P. (author), Jonkers, S. (author), Verhagen, H.L.M. (author), Perez, L. (author), Truëb, S. (author), Okkerse, W.J. (author), Liu, J. (author), Pan, X.C. (author), Zheng, L. (author), Wang, H. (author), Xu, R. (author), Sabel, C.E. (author)Two traffic scenarios to reduce CO2 emissions from road traffic in two European cities (Basel and Rotterdam) and two Chinese cities (Xi'an and Suzhou) were evaluated in terms of their impact on air quality. The two scenarios, one modelling a reduction of private vehicle kilometres driven by 10% on urban streets and the other modelling the...article 2014
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Eeftens, M. (author), Hoek, G. (author), Gruzieva, O. (author), Mölter, A. (author), Agius, R. (author), Beelen, R. (author), Brunekreef, B. (author), Custovic, A. (author), Cyrys, J. (author), Fuertes, E. (author), Heinrich, J. (author), Hoffmann, B. (author), De Hoogh, K. (author), Jedynska, A. (author), Keuken, M. (author), Klümper, C. (author), Kooter, I. (author), Krämer, U. (author), Korek, M. (author), Koppelman, G.H. (author), Kuhlbusch, T.A.J. (author), Simpson, A. (author), Smit, H.A. (author), Tsai, M.Y. (author), Wang, M. (author), Wolf, K. (author), Pershagen, G. (author), Gehring, U. (author)BACKGROUND: Negative effects of long-term exposure to particulate matter (PM) on lung function have been shown repeatedly. Spatial differences in the composition and toxicity of PM may explain differences in observed effect sizes between studies. METHODS: We conducted a multicenter study in 5 European birth cohorts - BAMSE (Sweden), GINIplus and...article 2014