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Janssen, M. (author), van der Voort, H. (author), van Veenstra, A.F.E. (author)Many large transformation projects do not result in the outcomes desired or envisioned by the stakeholders. This type of project is characterised by dynamics which are both caused by and result of uncertainties and unexpected behaviour. In this paper a complex adaptive system (CAS) view was adopted in order to better understand project dynamics...article 2015
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Huijg, J.M. (author), van der Zouwe, N. (author), Crone, M.R. (author), Verheijden, M.W. (author), Middelkoop, B.J.C. (author), Gebhardt, W.A. (author)Background: The introduction of efficacious physical activity (PA) interventions in routine primary health care (PHC) is a complex process. Understanding factors influencing the process can enhance the development of successful introduction strategies. Purpose: The aim of this qualitative study was to explore stakeholders’ perceptions on factors...article 2015
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Blanson Henkemans, O. (author), Keij, M. (author), Beckers, M. (author), Kamphuis, M. (author)How can preventive youth health care profit from the benefits of the StartingTogether App? This article discusses national implementation of the App. The results : increased familiarity of the App, nurses who felt more equipped to use it, and region specific support.How can preventive youth health care profit from the benefits of the...article 2015
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Folmer, E. (author), Kulcsar, I.Z. (author), Roes, J. (author)This paper presents the current results of an ongoing research about a new data standards development concept. The concept is called Instant Standard referring to the pressure that is generated by shrinking the length of the standardization process. Based on this concept it is estimated that the development time is reduced by over 50% while...conference paper 2013
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Huijg, J.M. (author), Crone, M.R. (author), Verheijden, M.W. (author), van der Zouwe, N. (author), Middelkoop, B.J. (author), Gebhardt, W.A. (author)Background: The introduction of efficacious physical activity interventions in primary health care is a complex process. Understanding factors influencing the process can enhance the development of effective introduction strategies. This Delphi study aimed to identify factors most relevant for the adoption, implementation, and continuation of...article 2013
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Posthumus, B. (author), Aarnoudse, R. (author), Stroek, C. (author)Dissemination of information has always been an important topic in agriculture as information educates farmers and helps them to make the right decisions on agricultural practices and marketing. The main objective of this research is to explore how social networks could be deployed in order to stimulate the diffusion of mobile agricultural...conference paper 2013
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Folmer, E.J.A. (author), Oude Luttighuis, P.H.W.M. (author), van Hillegersberg, J. (author)The adoption of standards to improve interoperability in the automotive, aerospace, shipbuilding and other sectors could save billions. While interoperability standards have been created for a number of industries, problems persist, suggesting a lack of quality of the standards themselves. The issue of semantic standard quality is not often...article 2011
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Dumay, A.C.M. (author), Mooij, R. (author), Blank, J.L.T. (author), TNO Kwaliteit van Leven (author)This study aims to assess the adoption potential of healthcare innovations in their infancy. Such an assessment is useful, since the context of the innovations change rapidly as a result of the health care reform process. Successful innovations comply to a complex system of social, technical, and financial attributes. First we narrow down the...bookPart 2011
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Pennings, L.J. (author), Veugen, P.J.M. (author), de Korte, J.J. (author), TNO Informatie- en Communicatietechnologie (author)The success of an intelligent sensor environment is mainly determined by the extent to which it is adopted by users. In order to understand how the adoption process works and when it is likely to be successful, we developed a general adoption model and applied it to the four main categories. Based on four case studies, we developed and tested...article 2010
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TNO Informatie- en Communicatietechnologie (author), Berends, W. (author), Folmer, E.J.A. (author)Nowadays businesses increasingly want to be interoperable so that they can collaborate with other organizations. Interoperability can be achieved through the use of business transaction standards, by which the organizations that use the standards collectively form a value added network. However the effectivity of these standards is largely...conference paper 2010
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TNO Informatie- en Communicatietechnologie (author), Folmer, E.J.A. (author), Berends, W. (author), Oude Luttighuis, P. (author), van Hillegersberg, J. (author), Lammers, R. (author)This paper contains the results of a systematic literature review executed to determine the coverage of transaction standards in top information systems (IS) and management journals. Specifically, it aims to identify a research gap with respect to this topic. The top 25 journals are thoroughly searched and the selected publications are...bookPart 2010
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Kel, J.M. (author), Slütter, B. (author), Drijfhout, J.W. (author), Koning, F. (author), Nagelkerken, L. (author), TNO Kwaliteit van Leven (author)Tolerance to experimental autoimmune encephalomyelitis (EAE) in SJL mice can be induced by immunization with a mannosylated form of the proteolipid protein (M-PLP139-151), despite the presence of CFA. The state of tolerance is characterized by poor delayed-type hypersensitivity responses and the absence of clinical EAE symptoms. In vivo...article 2008
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Pals, N. (author), Steen, M.G.D. (author), Langley, D.J. (author), Kort, J. (author)This paper addresses three different approaches which can be employed to adequately answer different questions faced by product developers. These approaches differ in the ways users themselves are involved in developing the "real" user perspective. In participatory design, products and product concepts are developed together with users so that...article 2008
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Montalvo Corral, C. (author)Cleaner technologies (CT) have recently received much attention in diverse media and policy agendas. This comes out of the clear role they play in environmental protection and sustainability and the large potential to contribute to economic growth and competitiveness. The realization of both potentials depends on the level diffusion and...article 2008
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Fledderus, E.R. (author), TNO Informatie- en Communicatietechnologie (author)Technology, such as IMT-2000 and IMT-A, plays an important role in our society. A number of prominent authors and thinkers have judged the impact of technology as being increasingly radical. This paper connects different visions on technology, thereby bringing different perspectives on innovation into line. An important motivation for this paper...article 2008
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Blanson Henkemans, O.A. (author), Rogers, W.A. (author), Fisk, A.D. (author), Neerincx, M.A. (author), Lindenberg, J. (author), van der Mast, C.A.P.G. (author)Objectives: We developed an adaptive computer assistant for the supervision of diabetics' self-care, to support limiting illness and need for acute treatment, and improve health literacy. This assistant monitors self-care activities logged in the patient's electronic diary. Accordingly, it provides context-aware feedback. The objective was to...article 2008
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Pals, N. (author), Steen, M.G.D. (author), Langley, D.J. (author), Kort, J. (author), TNO Informatie en Communicatietechnologie (author), ICT (author)This paper addresses three different approaches which can be employed to adequately answer different questions faced by product developers. These approaches differ in the ways users themselves are involved in developing the "real" user perspective. In participatory design, products and product concepts are developed together with users so that...article 2008
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Verbeek, R. (author), van Dongen, H. (author), Wawrousek, E.F. (author), Amor, S. (author), van Noort, J.M. (author), TNO Kwaliteit van Leven TNO Defensie en Veiligheid (author)While myelin-reactive T cells are widely believed to play a pathogenic role in multiple sclerosis (MS), no substantial differences appear to exist in T-cell responses to myelin antigens between MS patients and healthy subjects. As an example, indistinguishable peripheral T-cell responses and serum antibody levels have been found in MS patients...article 2007
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de Jong, A.M. (author), Vink, P. (author)A step-by-step approach to better work, aimed at reducing the physical workload of glaziers, is evaluated. In three small-sized companies mechanical aids were developed with strong commitment from management. Glaziers from these three companies prioritized problems, selected solutions and tested the solutions. A steering group with...article 2000
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van Stipdonk, M.J.B. (author), Willems, A.A. (author), Verbeek, R. (author), Boog, C.J.P. (author), van Noort, J.M. (author), TNO Preventie en Gezondheid (author)The myelin-associated stress protein αB-crystallin triggers strong proliferative responses and IFN-γ production by human T cells and it is considered a candidate autoantigen in multiple sclerosis. In this study we examined the capacity of αB-crystallin or peptides derived thereof to induce experimental autoimmune encephalomyelitis (EAE) in SJL...article 2000