Searched for: subject%3A%22Aberrations%22
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Schoen, E.D. (author), Eendebak, P.T. (author), Vazquez, A.R. (author), Goos, P. (author)
Conference designs are n×k matrices, k ≤ n,with orthogonal columns, one zero in each column, at most one zero in each row, and−1 and+1 entries elsewhere. Conference designs with k = n are called conference matrices. Definitive screening designs (DSDs) are constructed by folding over a conference design and adding a row vector of zeros.We...
article 2022
document
Eendebak, P.T. (author), Schoen, E.D. (author), Vazquez, A.R. (author), Goos, P. (author)
The first dedicated algorithm to enumerate even-odd designs of strength 3 is presented. Such designs cannot be constructed by folding over smaller designs, but they may permit simultaneous estimation of many more two-factor interactions than designs that can be constructed by folding over. In the algorithm, enumeration is restricted to the...
article 2022
document
Caron, J.F. (author), Ceccotti, T. (author), Bäumer, S.M.B. (author)
In this invited paper, a simple and efficient matrix formalism is presented for computing aberrations in plane-parallel freeform mirror systems. The approach is flexible and can be easily generalized to arbitrary aberration orders and/or to systems with different symmetries. As an illustration, we derive analytical expressions for all second-...
conference paper 2021
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Schoen, E.D. (author), Vo-Thanh, N. (author), Goos, P. (author)
Much research has been done concerning 24-run orthogonal two-level designs involving 3–23 factors and 28-run orthogonal two-level designs involving 3–27 factors. The focus of this research was on completely randomized screening designs and led to lists of recommended designs for each number of factors. When using the recommended designs, there...
article 2019
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Vazquez, A.R. (author), Goos, P. (author), Schoen, E.D. (author)
Two-level orthogonal arrays of N runs, k factors, and a strength of 3 provide suitable fractional factorial designs in situations where many of the main effects are expected to be active, as well as some two-factor interactions. If they consist of N/2 mirror image pairs, these designs are fold-over designs. They are called even and provide at...
article 2019
document
Kuiper, S. (author), Doelman, N.J. (author), Human, J.D. (author), Saathof, R. (author), Klop, W.A. (author), Maniscalco, M.P. (author)
TNO is developing Deformable Mirror (DM) technology, targeted for aberration correction in high-end Adaptive Optics (AO) applications in the field of lithography, astronomy, space and laser communication. The heart of this deformable mirror technology is a unique actuator technology based on the variable reluctance principle. The main advantages...
conference paper 2018
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Kuiper, S. (author), Doelman, N.J. (author), Overtoom, T. (author), Nieuwkoop, E. (author), Russchenberg, T. (author), van Riel, M.J.C.M. (author), Wildschut, J.A. (author), Baeten, M.J.J. (author), Spruit, W.E.T. (author), Brinkers, S. (author), Human, J.D. (author)
To increase the collecting power and to improve the angular imaging resolution, space telescopes are evolving towards larger primary mirrors. The aerial density of the telescope mirrors needs to be kept low, however, to be compatible with the launch requirements. A light-weight (primary) mirror will introduce additional optical aberrations to...
conference paper 2017
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Schoen, E.D. (author), Vo-Thanh, N. (author), Goos, P. (author)
The potential of two-level orthogonal designs to fit models with main effects and two-factor interaction effects is commonly assessed through the correlation between contrast vectors involving these effects. We study the complete catalog of nonisomorphic orthogonal two-level 24-run designs involving 3–23 factors and we identify the best few...
article 2017
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Luijten, M. (author), Olthof, E.D. (author), Hakkert, B.C. (author), Rorije, E. (author), van der Laan, J.-W. (author), Woutersen, R.A. (author), van Benthem, J. (author)
Assessment of genotoxic and carcinogenic potential is considered one of the basic requirements when evaluating possible human health risks associated with exposure to chemicals. Test strategies currently in place focus primarily on identifying genotoxic potential due to the strong association between the accumulation of genetic damage and cancer...
article 2016
document
Garthoff, J.A. (author), Heemskerk, S. (author), Hempenius, R.A. (author), Lina, B.A.R. (author), Krul, C.A.M. (author), Koeman, J.H. (author), Speijers, G.J.A. (author), TNO Kwaliteit van Leven (author)
Pectin-derived acidic oligosaccharides (pAOS) are non-digestible carbohydrates to be used in infant formulae and medical nutrition. To support its safety, the genotoxic potential of pAOS was evaluated. pAOS was not mutagenic in the Ames test. Positive results were obtained in the chromosome aberration test only at highly cytotoxic concentrations...
article 2010
document
van Aken, R.H. (author), Maas, D.J. (author), Hagen, C.W. (author), Barth, J.E. (author), Kruit, P. (author), TNO Industrie en Techniek (author)
The low-voltage foil corrector is a novel type of foil aberration corrector that can correct for both the spherical and chromatic aberration simultaneously. In order to give a realistic example of the capabilities of this corrector, a design for a low-voltage scanning electron microscope with the low-voltage foil corrector is presented. A fully...
article 2010
document
Ponstein-Simarro Doorten, A.Y. (author), van de Wiel, J.A.G. (author), Jonker, D. (author), TNO Kwaliteit van Leven (author)
Tensguard™ is a milk protein hydrolysate containing the lactotripeptide IPP. It is derived from cow's milk, which is present in the human diet and has a safe history of consumption. The final Tensguard™ product, a supplement or a functional food ingredient, is intended for use by people who want to follow a healthy diet and lifestyle in order to...
article 2009
document
Weijenberg, M.P. (author), Lüchtenborg, M. (author), de Goeij, A.F.P.M. (author), Brink, M. (author), van Muijen, G.N.P. (author), de Bruïne, A.P. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Objective: To investigate baseline fat intake and the risk of colon and rectal tumors lacking MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) repair gene expression and harboring mutations in the APC (adenomatous polyposis coli) tumor suppressor gene and in the KRAS (v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) oncogene....
article 2007
document
Liebsch, M. (author), Spielmann, H. (author), Pape, W. (author), Krul, C. (author), Deguercy, A. (author), Eskes, C.A.M. (author), TNO Kwaliteit van Leven (author)
Regulatory requirements: According to the current Notes for Guidance of the Scientific Committee on Cosmetic Products and Non-Food Products (SCCNFP), cosmetic ingredients and mixtures of ingredients absorbing UV light (in particular UV filter chemicals used, for example, to ensure the light stability of cosmetics or used in sun protection...
article 2005
document
Maurici, D. (author), Aardema, M. (author), Corvi, R. (author), Kleber, M. (author), Krul, C.A.M. (author), Laurent, C. (author), Loprieno, N. (author), Pasanen, M. (author), Pfuhler, S. (author), Phillips, B. (author), Sabbioni, E. (author), Sanner, T. (author), Vanparys, P. (author), TNO Kwaliteit van Leven TNO Voeding (author)
article 2005
document
Nijkerk, M.D. (author), Kruit, P. (author)
Computations of space charge limited currents from thermionic emitters often rely on simple one-dimensional analytical models. The geometric limitations of these models are circumvented by applying the models locally over the emitter surface. The validity of the analytical models is compromised by the presence of surface roughness that...
article 2004
document
Bär, A. (author), Krul, C.A.M. (author), Jonker, D. (author), de Vogel, N. (author), TNO Voeding (author)
Alpha-cyclodextrin glucosyltransferase (α-CGTase, EC 2.4.1.19) is an amylolytic enzyme used for the production of α-cyclodextrin (α-CD), a novel, soluble dietary fiber, from food-grade starch. The safety of an α-CGTase preparation obtained by batch fermentation from a recombinant strain of Escherichia coli K12 harboring the α-CGTase gene from...
article 2004
document
Wijnands, M.V.W. (author), van Erk, M.J. (author), Doornbos, R.P. (author), Krul, C.A.M. (author), Woutersen, R.A. (author)
The effects of different dietary compounds on the formation of aberrant crypt foci (ACF) and colorectal tumours and on the expression of a selection of genes were studied in rats. Azoxymethane-treated male F344 rats were fed either a control diet or a diet containing 10% wheat bran (WB), 0.2% curcumin (CUR), 4% rutin (RUT) or 0.04% benzyl...
article 2004
document
Bingham, D.R. (author), Schoen, E.D. (author), Sitter, R.R. (author), Technisch Physische Dienst TNO - TH (author)
When it is impractical to perform the experimental runs of a fractional factorial design in a completely random order, restrictions on the randomization can be imposed. The resulting design is said to have a split-plot, or nested, error structure. Similarly to fractional factorials, fractional factorial split-plot designs can be ranked by using...
article 2004
document
de Jong, A.N. (author)
When images are made of distant targets over long atmospheric paths, local variations of the refractive index of the air may lead to severe optical distortions and aberrations. An extreme example of such variations is the stream of hot exhaust gases on ships. The performance of infrared and optical sensors, mounted on elevated platforms on board...
conference paper 2004
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