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Novel concepts for preparation of reference materials as whole water samples for priority substances at nanogram-per-liter level using model suspended particulate matter and humic acids

Elordui-Zapatarietxe, S. (author), Fettig, I. (author), Philipp, R. (author), Gantois, F. (author), Lalère, B. (author), Swart, C. (author), Petrov, P. (author), Goenaga-Infante, H. (author), Vanermen, G. (author), Boom, G. (author), Emteborg, H. (author)

One of the unresolved issues of the European Water Framework Directive is the unavailability of realistic water reference materials for the organic priority pollutants at low nanogram-per-liter concentrations. In the present study, three different types of ready-to-use water test materials were developed for polycyclic aromatic hydrocarbons ...

article 2015

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Generation and characterization of diesel engine combustion emissions from petroleum diesel and soybean biodiesel fuels and application for inhalation exposure studies.

Mutlu, E. (author), Nash, D.G. (author), King, C. (author), Krantz, T.Q. (author), Preston, W.T. (author), Kooter, I.M. (author), Higuchi, M. (author), DeMarini, D. (author), Linak, W.P. (author), Ian Gilmour, M. (author)

Biodiesel made from the transesterification of plant- and animal-derived oils is an important alternative fuel source for diesel engines. Although numerous studies have reported health effects associated with petroleum diesel emissions, information on biodiesel emissions are more limited. To this end, a program at the U.S. EPA assessed health...

article 2015

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Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity

Walczak, A.P. (author), Kramer, E. (author), Hendriksen, P.J.M. (author), Tromp, P. (author), Helsper, J.P.F.G. (author), van der Zande, M. (author), Rietjens, I.M.C.M. (author), Bouwmeester, H. (author)

Intestinal translocation is a key factor for determining bioavailability of nanoparticles (NPs) after oral uptake. Therefore, we evaluated three in vitro intestinal cell models of increasing complexity which might affect the translocation of NPs: a mono-culture (Caco-2 cells), a co-culture with mucus secreting HT29-MTX cells and a tri-culture...

article 2015

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Spatial variations of levoglucosan in four European study areas

Jedynska, A. (author), Hoek, G. (author), Wang, M. (author), Eeftens, M. (author), Cyrys, J. (author), Beelen, R. (author), Cirach, M. (author), De Nazelle, A. (author), Keuken, M. (author), Visschedijk, A. (author), Nystad, W. (author), Akhlaghi, H.M. (author), Meliefste, K. (author), Nieuwenhuijsen, M. (author), de Hoogh, K. (author), Brunekreef, B. (author), Kooter, I.M. (author)

Relatively little is known about long term effects of wood smoke on population health. A wood combustion marker - levoglucosan - was measured using a standardized sampling and measurement method in four European study areas (Oslo, The Netherlands, Munich/Augsburg, Catalonia) to assess within and between study area spatial variation. Levoglucosan...

article 2015

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Chemical chacterization of biofuel exhaust emissions

Jedynska, A.D. (author), Tromp, P.C. (author), Houtzager, M.M.G. (author), Kooter, I.M. (author)

Use of biodiesel is increasing following implementation of various policy instruments and a surge in demand due to growing urbanized populations. A series of experiments to characterize the chemical composition of emissions generated during combustion of petro-diesel (B0), biodiesel blends (B5, B10, B20), biodiesel (B100) and pure plant oil were...

article 2015

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Health effects of soy-biodiesel emissions: Mutagenicity-emission factors.

Mutlu, E. (author), Warren, S.H. (author), Matthews, P.P. (author), King, C. (author), Walsh, L. (author), Kligerman, A.D. (author), Schmid, J.E (author), Janek, D. (author), Kooter, I.M. (author), Linak, W.P (author), Gilmour, M.I (author), DeMarini, D.M. (author)

CONTEXT: Soy biodiesel is the predominant biodiesel fuel used in the USA, but only a few, frequently conflicting studies have examined the potential health effects of its emissions.

article 2015

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The effect of mercuric chloride treatment as biocide for herbaria on the indoor air quality

Havermans, J.B.G.A. (author), Dekker, R. (author), Sportel, R. (author)

One of the most previous conservation treatments for plant specimen in herbarium collections was mercuric chloride (HgCl2). However, due time HgCl2 may decompose and it may cause (metallic) mercury (Hg) emission. Hg vapour in indoor air should be avoided as mercury poisoning can already occur at levels of 6 μg/m3. Both field and laboratory...

article 2015

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Incident response monitoring technologies for aircraft cabin

Havermans, J.B.G.A. (author), Houtzager, M.M.G. (author), Jacobs, P. (author)

The Netherlands Organization for Applied Scientific Research (TNO) was granted by ASHRAE (1306-RP) to conduct scientfic review and feasibility analysis of technologies and methods for measuring aircraft power system contaminants in the cabin air during unanticipated adverse incidents. In particular, the following specific objectives were...

article 2015

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Translocation of positively and negatively charged polystyrene nanoparticles in an in vitro placental model

Kloet, S.K. (author), Walczak, A.P. (author), Louisse, J. (author), van den Berg, H.H.J. (author), Bouwmeester, H. (author), Tromp, P. (author), Fokkink, R.G. (author), Rietjens, I.M.C.M. (author)

To obtain insight in translocation of nanoparticles across the placental barrier, translocation was studied for one positively and two negatively charged polystyrene nanoparticles (PS-NPs) of similar size in an in vitro model. The model consisted of BeWo b30 cells, derived from a human choriocarcinoma grown on a transwell insert forming a cell...

article 2015

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Natural-cause mortality and long-term exposure to particle components: An Analysis of 19 European cohorts within the multi-center ESCAPE project

Beelen, R. (author), Hoek, G. (author), Raaschou-Nielsen, O. (author), Stafoggia, M. (author), Andersen, Z.J. (author), Weinmayr, G. (author), Hoffmann, B. (author), Wolf, K. (author), Samoli, E. (author), Fischer, P.H. (author), Nieuwenhuijsen, M.J. (author), Xun, W.W. (author), Katsouyanni, K. (author), Dimakopoulou, K. (author), Marcon, A. (author), Vartiainen, E. (author), Lanki, T. (author), Yli-Tuomi, T. (author), Oftedal, B. (author), Schwarze, P.E. (author), Nafstad, P. (author), de Faire, U. (author), Pedersen, N.L. (author), Östenson, C.-G. (author), Fratiglioni, L. (author), Penell, J. (author), Korek, M. (author), Pershagen, G. (author), Eriksen, K.T. (author), Overvad, K. (author), Sørensen, M. (author), Eeftens, M. (author), Peeters, P.H. (author), Meliefste, K. (author), Wang, M. (author), Bas Bueno-De-Mesquita, H. (author), Sugiri, D. (author), Krämer, U. (author), Heinrich, J. (author), De Hoogh, K. (author), Key, T. (author), Peters, A. (author), Hampel, R. (author), Concin, H. (author), Nagel, G. (author), Jaensch, A. (author), Ineichen, A. (author), Tsai, M.-Y. (author), Schaffner, E. (author), Probst-Hensch, N.M. (author), Schindler, C. (author), Ragettli, M.S. (author), Vilier, A. (author), Clavel-Chapelon, F. (author), Declercq, C. (author), Ricceri, F. (author), Sacerdote, C. (author), Galassi, C. (author), Migliore, E. (author), Ranzi, A. (author), Cesaroni, G. (author), Badaloni, C. (author), Forastiere, F. (author), Katsoulis, M. (author), Trichopoulou, A. (author), Keuken, M. (author), Jedynska, A. (author), Kooter, I.M. (author), Kukkonen, J. (author), Sokhi, R.S. (author), Vineis, P. (author), Brunekreef, B. (author)

Background: Studies have shown associations between mortality and long-term exposure to particulate matter air pollution. Few cohort studies have estimated the effects of the elemental composition of particulate matter on mortality. oBjectives: Our aim was to study the association between natural-cause mortality and long-term exposure to...

article 2015

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Protocol voor het valideren van nieuwe werkmethoden en/of innovatieve technieken met betrekking tot asbestverwijdering ten behoeve van het indelen in een risico-klasse (t.b.v. SMA-rt)

Spaan, S. (author), den Boeft, J. (author), Tempelman, J. (author), Schinkel, J.M. (author)

Dit protocol is opgesteld als onderdeel van het programma “Innovaties voor veilig werken met asbest”, dat TNO uitvoert in opdracht van het ministerie van Sociale zaken en Werkgelegenheid (SZW). Het doel van dit programma is het advisering van het ministerie van SZW met betrekking tot haar beleid rondom asbestverwijdering, het komen tot een state...

report 2015

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Protocol voor het bepalen van de concentratie aan respirabele asbestvezels in de lucht tijdens het op projectniveau uitvoeren van asbestverwijderingshandelingen

Spaan, S. (author), den Boeft, J. (author), Tempelman, J. (author), Schinkel, J.M. (author)

Dit protocol is opgesteld als onderdeel van het programma “Innovaties voor veilig werken met asbest”, dat TNO uitvoert in opdracht van het ministerie van Sociale zaken en Werkgelegenheid (SZW). Het doel van dit programma is het advisering van het ministerie van SZW met betrekking tot haar beleid rondom asbestverwijdering, het komen tot een state...

report 2015

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Health effects of soy-biodiesel emissions: Bioassay-directed fractionation for mutagenicity.

Mutlu, E. (author), Warren, S.H. (author), Matthews, P.P. (author), Schmid, J.E. (author), Kooter, I.M. (author), Linak, W.P. (author), Gilmour, I. (author), DeMarini, D.M. (author)

CONTEXT: Soy biodiesel is the predominant biodiesel in the USA, but there is little understanding of the classes of chemicals responsible for the mutagenicity of its emissions. OBJECTIVE: We determined some of the chemical classes responsible for the mutagenicity of the particulate matter (PM) of the emissions from petroleum diesel (B0) and...

article 2015

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Radiocarbon dating of late pleistocene marine shells from the southern North Sea

Busschers, F.S. (author), Wesselingh, F.P. (author), Kars, R.H. (author), Versluijs-Helder, M. (author), Wallinga, J. (author), Bosch, J.H.A. (author), Timmner, J. (author), Nierop, K.G.J. (author), Meijer, T. (author), Bunnik, F.P.M. (author), de Wolf, H. (author)

This article presents a set of Late Pleistocene marine mollusk radiocarbon (AMS) age estimates of 30-50 14C kyr BP, whereas a MIS5 age (>75 ka) is indicated by quartz and feldspar OSL dating, biostratigraphy, U-Th dating, and age-depth relationships with sea level. These results indicate that the 14C dates represent minimum ages. The age...

article 2014

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Development of land use regression models for elemental, organic carbon, PAH, and hopanes/steranes in 10 ESCAPE/TRANSPHORM European study areas

Jedynska, A. (author), Hoek, G. (author), Wang, M. (author), Eeftens, M. (author), Cyrys, J. (author), Keuken, M. (author), Ampe, C. (author), Beelen, R. (author), Cesaroni, G. (author), Forastiere, F. (author), Cirach, M. (author), de Hoogh, K. (author), de Nazelle, A. (author), Nystad, W. (author), Declercq, C. (author), Eriksen, K.T. (author), Dimakopoulou, K. (author), Lanki, T. (author), Meliefste, K. (author), Nieuwenhuijsen, M.J. (author), Yli-Tuomi, T. (author), Raaschou-Nielsen, O. (author), Brunekreef, B. (author), Kooter, I.M. (author)

Land use regression (LUR) models have been used to model concentrations of mainly traffic-related air pollutants (nitrogen oxides (NOx), particulate matter (PM) mass or absorbance). Few LUR models are published of PM composition, whereas the interest in health effects related to particle composition is increasing. The aim of our study was to...

article 2014

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Effects of silver nanoparticles (NM-300K) on Lumbricus rubellus earthworms and particle characterization in relevant test matrices including soil

van der Ploeg, M.J.C. (author), Handy, R.D. (author), Waalewijn-Kool, P.L. (author), van den Berg, J.H.J. (author), Herrera Rivera, Z.E. (author), Bovenschen, J. (author), Molleman, B. (author), Baveco, J.M. (author), Tromp, P. (author), Peters, R.J.B. (author), Koopmans, G.F. (author), Rietjens, I.M.C.M. (author), van den Brink, N.W. (author)

The impact of silver nanoparticles (AgNP; at 0mg Ag/kg, 1.5mg Ag/kg, 15.4mg Ag/kg, and 154mg Ag/kg soil) and silver nitrate (AgNO3; 15.4mg Ag/kg soil) on earthworms, Lumbricus rubellus, was assessed. A 4-wk exposure to the highest AgNP treatment reduced growth and reproduction compared with the control. Silver nitrate (AgNO3) exposure also...

article 2014

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The impact of a historical conservation method for the preservation of entomological collections on the indoor air quality of repositories

Havermans, J.B.G.A. (author), Dekker, R. (author), Correl, R. (author)

conference paper 2014

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Spatial variations of PAH, hopanes/steranes and EC/OC concentrations within and between European study areas

Jedynska, A. (author), Hoek, G. (author), Eeftens, M. (author), Cyrys, J. (author), Keuken, M. (author), Ampe, C. (author), Beelen, R. (author), Cesaroni, G. (author), Forastiere, F. (author), Cirach, M. (author), de Hoogh, K. (author), de Nazelle, A. (author), Madsen, C. (author), Declercq, C. (author), Eriksen, K.T. (author), Katsouyanni, K. (author), Akhlaghi, H.M. (author), Lanki, T. (author), Meliefste, K. (author), Nieuwenhuijsen, M. (author), Oldenwening, M. (author), Pennanen, A. (author), Raaschou-Nielsen, O. (author), Brunekreef, B. (author), Kooter, I.M. (author)

Limited information is available on the contribution of organic components in particulate matter to health effects related to fine particles. Spatial variability of specific fine particle organic components has not been assessed with consistent methods. The aim of this paper is to assess spatial variation of organic components of fine particles...

article 2014

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Spatial variability of trace elements and sources for improved exposure assessment in Barcelona

Minguillón, M.C. (author), Cirach, M. (author), Hoek, G. (author), Brunekreef, B. (author), Tsai, M. (author), de Hoogh, K. (author), Jedynska, A. (author), Kooter, I.M. (author), Nieuwenhuijsen, M. (author), Querol, X. (author)

Trace and major elements concentrations in PM10 and PM2.5 were measured at 20 sites spread in the Barcelona metropolitan area (1 rural background, 6 urban background, 13 road traffic sites) and at 1 reference site. Three 2-week samples per site and size fraction were collected during 2009 using low volume samplers, adding a total of 120 samples....

article 2014

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Characterization of titanium dioxide nanoparticles in food products: Analytical methods to define nanoparticles

Peters, R.J.B. (author), van Bemmel, G. (author), Herrera-Rivera, Z. (author), Helsper, H.P.F.G. (author), Marvin, H.J.P. (author), Weigel, S. (author), Tromp, P.C. (author), Oomen, A.G. (author), Rietveld, A.G. (author), Bouwmeester, H. (author)

Titanium dioxide (TiO2) is a common food additive used to enhance the white color, brightness, and sometimes flavor of a variety of food products. In this study 7 food grade TiO2 materials (E171), 24 food products, and 3 personal care products were investigated for their TiO 2 content and the number-based size distribution of TiO2 particles...

article 2014