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de Haas, E.M. (author), Kraak, M.H.S. (author), TNO Kwaliteit van Leven (author)The absence of species in polluted sediments does not necessarily imply exclusion due to toxicity. Other factors, like for instance food availability and oxygen content, could also partly cause their absence. Hence, knowledge of the (combinations of) factors acting on individual organisms is essential in order to understand how populations can...article 2008
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- Janssen, S.A. (author), Miedema, H.M.E. (author), TNO Bouw en Ondergrond (author) conference paper 2008
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Zerp, S.F. (author), Vink, S.R. (author), Ruiter, G.A. (author), Koolwijk, P. (author), Peters, E. (author), van der Luit, A.H. (author), de Jong, D. (author), Budde, M. (author), Bartelink, H. (author), van Blitterswijk, W.J. (author), Verheij, M. (author), TNO Kwaliteit van Leven (author)Synthetic alkylphospholipids (APLs), such as edelfosine, miltefosine and perifosine, constitute a new class of antineoplastic compounds with various clinical applications. Here we have evaluated the antiangiogenic properties of APLs. The sensitivity of three types of vascular endothelial cells (ECs) (bovine aortic ECs, human umbilical vein ECs...article 2008
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- Larbi, J.A. (author), Siemes, A.J.M. (author), Polder, R.B. (author), TNO Bouw en Ondergrond (author) bookPart 2008
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Bloom, J.G.P. (author), Dijkstra, F.H. (author), Volker, A.W.F. (author), TNO Industrie en Techniek (author)Traditionally, ultrasonic inspection methods are developed using extensive lab measurements. This approach provides limited insight in the interaction of waves with artificial and realistic defects. However, for a thorough insight in the factors that determine the reliability it is necessary to understand the wave field inside the object of...conference paper 2008
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Li, P. (author), Aristimuno, P.X. (author), Arrazola, P.J. (author), Hoogstrate, A.M. (author), Oosterling, J.A.J. (author), Langen, H.H. (author), TNO Industrie en Techniek (author)Surface roughness is a key parameter in evaluation of engineering surface in macro scale; in case of micromilling, it is of even greater importance because the magnitude of the roughness can be comparable with the workpiece tolerance, and will have a direct impact on the quality of the microproducts. This paper presents the preliminary results...conference paper 2008
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Adams, T.B. (author), Gavin, C.L. (author), Taylor, S.V. (author), Waddell, W.J. (author), Cohen, S.M. (author), Feron, V.J. (author), Goodman, J. (author), Rietjens, I.M.C.M. (author), Marnett, L.J. (author), Portoghese, P.S. (author), Smith, R.L. (author), TNO Kwaliteit van Leven (author), KvL (author)This publication is the 12th in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavoring substances under conditions of intended use. Since then, the number of flavoring...article 2008
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van den Berg, F.H.A. (author), van der Eerden, F.J.M. (author)Sound propagation is affected by the meteorological situation prescribed by the vertical gradient of wind and temperature. In coastal areas like a harbour these gradients can vary along the sound propagation path, especially at water-land crossings. As a result, the sound propagation in these areas cannot be calculated with standard acoustic...conference paper 2008
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- Amelink-Verburg, M.P. (author), Buitendijk, S.E. (author), TNO Kwaliteit van Leven (author) article 2008
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Wijlhuizen, G.J. (author), Chorus, A.M.J. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)Background: In their letters to the editor, Lacherez et al. [Lacherez, P.F., Wood, J.M., Kerr, G.K., 2007. Does activity level mediate or suppress the association between fear of falling and falls? Prev. Med. 31; (Electronic publication ahead of print)] and Hafeman and Schwartz [Hafeman, D., Schwartz, S., 2007. Assessing mediation: The necessity...article 2008
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van den Bosch, S. (author), Rotmans, J. (author), TNO Bouw en Ondergrond (author)De publicatie ‘Deepening, Broadening and Scaling Up: A Framework for Steering Transition Experiments’ is onlangs uitgegeven door het Kenniscentrum voor duurzame systeeminnovaties en transities (KCT). Het KCT is een samenwerkingsverband tussen TNO en de Erasmus Universiteit. Deze publicatie is een vervolg op de uitgave ‘Transitie-experimenten:...book 2008
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- Diederen, A.M. (author), TNO Defensie en Veiligheid (author) conference paper 2008
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Alferdinck, J.W.A.M. (author), TNO Defensie en Veiligheid (author)Een van de visuele taken bij het rijden bij nacht is het tijdig reageren op potentieel gevaarlijke objecten in het verkeersbeeld. Vaak worden deze objecten waargenomen bij schemerige (mesopische) lichtniveaus in de periferie van het visuele veld. Omdat er nog geen geschikte meetmethoden zijn voor deze mesopische lichtniveaus (luminanties tussen...conference paper 2008
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- Koek, M.M. (author), Muilwijk, B. (author), van Stee, L.L.P. (author), Hankemeier, T. (author), TNO Kwaliteit van Leven (author) article 2008
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van Delden, H. (author), Valkering, P. (author), Luja, P. (author), van de Lindt, M. (author), Neevel, V. (author), TNO Industrie en Techniek (author)Decision making in spatial planning often takes place in a complex and illdefined context. It includes a large number of actors, factors and -often uncertain- relations. Each of the actors or stakeholders has his or her individual perceptions, values and priorities. This paper presents the TOPIC system, which aims to support this process by...conference paper 2008
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Cremers, A.H.M. (author), de Jong, J.G.M. (author), van Balken, J.S. (author), TNO Defensie en Veiligheid (author)One of the major challenges in current user interface research and development is the accommodation of diversity in users and contexts of use in order to improve the self-efficacy of citizens. A common banking service, which should be designed for diversity, is the Automated Teller Machine (ATM). This paper describes the various user-centered...conference paper 2008
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Planje, W.G. (author), TNO Bouw en Ondergrond (author)De aanleg van een aquifer is duur en ook niet overal mogeliik.TNO heeft daarom andere technieken onderzocht voor seizoensopslag van warmte en koude. Wat bliikt? De aquifer is veruit het meest efficiëntarticle 2008
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de Haan, W. (author), Out, R. (author), Berbée, J.F.P. (author), van der Hoogt, C.C. (author), Dijk, K.W.v. (author), van Berkel, T.J.C. (author), Romijn, J.A. (author), Wouter Jukema, J. (author), Havekes, L.M. (author), Rensen, P.C.N. (author), TNO Kwaliteit van Leven (author)Apolipoprotein CI (apoCI) has been suggested to influence HDL metabolism by activation of LCAT and inhibition of HL and CETP. However, the effect of apoCI on scavenger receptor BI (SR-BI)-mediated uptake of HDL-cholesteryl esters (CE), as well as the net effect of apoCI on HDL metabolism in vivo is unknown. Therefore, we evaluated the effect of...article 2008
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Commissaris, D.A.C.M. (author), Blok, M. (author), Bosch, T. (author), Konemann, R. (author), Bronkhorst, R. (author), TNO Kwaliteit van Leven (author)TNO and BMA Ergonomics are developing a so-called smart office chair. This chair is supposed to provide feedback on postures and movements during seated office work. The feedback should enable the user (i.e. the worker doing VDU tasks) to perform his or her work with less discomfort and in a more productive way. One part of this project is a...conference paper 2008
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- van Harmelen, T. (author), Klok, L. (author), Dopp, S. (author), Dolevo, R.S.P.P. (author), Janssen, S.A. (author), TNO Bouw en Ondergrond (author) article 2008