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Martens, M.K. (author), van Assema, P. (author), Paulussen, T.G.W.M. (author), van Breukelen, G. (author), Brug, J. (author), TNO Kwaliteit van Leven (author)Objective: The aim of this study was to assess the behavioural effects of a schoolbased healthful diet promotion intervention implemented in lower vocational schools. Design: A cluster-randomised pre-test–post-test experimental design was used, and data were collected by means of written questionnaires. Setting: Students of 18 Dutch lower...article 2007
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Rodrigues Pereira, R. (author), TNO Kwaliteit van Leven (author)0-19, PZ.article 2007
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Männistö, S. (author), Yaun, S.S. (author), Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.O. (author), Albanes, D. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cerhan, J.R. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Virtamo, J. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Dietary carotenoids have been hypothesized to protect against epithelial cancers. The authors analyzed the associations between intakes of specific carotenoids (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein + zeaxanthin, and lycopene) and risk of colorectal cancer using the primary data from 11 cohort studies carried out in North...article 2007
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Ainslie, M.A. (author), TNO Defensie en Veiligheid (author)Multipath ocean reverberation originating from the seabed in shallow isovelocity water, with particular attention to its information content in the cylindrical spreading and mode stripping regions, is considered. The reverberation is evaluated using Weston's flux integral method, both analytically with various simplifying approximations and...article 2007
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van Dijk, D. (author)Met de invoering op 1 januari 2008 van de EPBD wordt in ons land het energielabel verplicht. Dit label voor de bestaande bouw is nieuw. Voor de nieuwbouw kent Nederland al de EPN. Al enige tijd werkt NEN aan een norm die de huidige EPN-normen voor een woning- en utiliteitsbouw gaat integreren met de Europese EPDB-normen. Dit wordt de Energie...article 2007
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Jansen, N.W.D. (author), Roosendaal, G. (author), Bijlsma, J.W.J. (author), de Groot, J. (author), Lafeber, F.P.J.G. (author), TNO Kwaliteit van Leven (author)Objective. Joint bleeding, or hemarthrosis, leads in time to severe joint damage. This study was carried out to test the in vitro thresholds of exposure time and concentration that lead to irreversible joint damage, to add to the discussion on the usefulness of aspiration of the joint after a hemorrhage. Methods. Explants of healthy human...article 2007
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Fabriek, B.O. (author), Møller, H.J. (author), Vloet, R.P.M. (author), van Winsen, L.M. (author), Hanemaaijer, R. (author), Teunissen, C.E. (author), Uitdehaag, B.M.J. (author), van den Berg, T.K. (author), Dijkstra, C.D. (author), TNO Kwaliteit van Leven (author)The scavenger receptor CD163 is selectively expressed on tissue macrophages and human monocytes. CD163 has been implicated to play a role in the clearance of hemoglobin and in the regulation of cytokine production by macrophages. Membrane CD163 can be cleaved by matrix metalloproteinases (MMP) resulting in soluble CD163 (sCD163). In the present...article 2007
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Veugen, P.J.M. (author), TNO Informatie- en Communicatietechnologie (author)The class of multiple-repetition strategies is known to achieve capacity for specific discrete memorylesschannels with noiseless feedback. We show, given an arbitrary discrete memoryless channel with noiselessfeedback, that the repetition parameters should be chosen close to the self information of a transmissionerror to maximise the...article 2007
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van Weel, V. (author), Toes, R.E.M. (author), Seghers, L. (author), Deckers, M.M.L. (author), de Vries, M.R. (author), Eilers, P.H. (author), Sipkens, J. (author), Schepers, A. (author), Eefting, D. (author), van Hinsbergh, V.W.M. (author), van Bockel, J.H. (author), Quax, P.H.A. (author), TNO Kwaliteit van Leven (author)OBJECTIVE - The immune system is thought to play a crucial role in regulating collateral circulation (arteriogenesis), a vital compensatory mechanism in patients with arterial obstructive disease. Here, we studied the role of lymphocytes in a murine model of hindlimb ischemia. METHODS AND RESULTS - Lymphocytes, detected with markers for NK1.1,...article 2007
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Fransman, W. (author), Roeleveld, N. (author), Peelen, S. (author), de Kort, W. (author), Kromhout, H. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)BACKGROUND: Nurses and other hospital workers are exposed to antineoplastic drugs during daily activities. Previous studies suggest that antineoplastic drugs at occupational exposure levels may be toxic to reproduction, but these studies are not consistent or conclusive. METHODS: Self-administered questionnaires were completed by 4393 exposed...article 2007
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- de Bruin-Hordijk, T. (author), de Groot, E. (author) article 2007
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- Lubelli, B.A. (author), van Hees, R.P.J. (author), Groot, C. (author), Gunneweg, J. (author) article 2007
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van Wendel de Joode, B. (author), Vermeulen, R. (author), Heederik, D. (author), van Ginkel, K. (author), Kromhout, H. (author), TNO Kwaliteit van Leven (author)We performed an exploratory study to evaluate 2 self-administered questionnaires assessing hand dermatitis and investigate a possible exposure-response relationship between dermal exposure to semi-synthetic metalworking fluids (SMWF) and dermatitis. In a cross-sectional survey on dermatitis, a symptom-based questionnaire and a picture-based skin...article 2007
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Hosli, E. (author), Detmar, S. (author), Raat, H. (author), Bruil, J. (author), Vogels, T. (author), Verrips, E. (author), TNO Kwaliteit van Leven (author)The Child Health Questionnaire (CHQ)-87-item child and adolescent self-report (CF87) is an increasingly used health-related quality-of-life instrument for measuring the self-perceived physical and psychosocial well-being of children aged 10 years and older. The aims of this study were to evaluate structure, reliability and validity of the Dutch...article 2007
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Fest, E.P.M.J. (author), Temminghoff, E.J.M. (author), Griffioen, J. (author), van der Grift, B. (author), van Riemsdijk, W.H. (author), TNO Bouw en Ondergrond (author)Aluminium has received great attention in the second half of the 20th century, mainly in the context of the acid rain problem mostly in forest soils. In this research the effect of land use and depth of the groundwater on Al, pH and DOC concentration in groundwater under Dutch sandy soils has been studied. Both pH and DOC concentration play a...article 2007
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Damsten, M.C. (author), Commandeur, J.N.M. (author), Fidder, A. (author), Hulst, A.G. (author), Touw, D. (author), Noort, D. (author), Vermeulen, N.P.E. (author), TNO Defensie en Veiligheid (author)Covalent binding of reactive electrophilic intermediates to proteins is considered to play an important role in the processes leading to adverse drug reactions and idiosyncratic drug reactions. Consequently, both for the discovery and the development of new drugs, there is a great interest in sensitive methodologies that enable the detection of...article 2007
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Wang, Y. (author), Xu, H. (author), Wei, X. (author), Chai, C. (author), Xiao, Y. (author), Zhang, Y. (author), Chen, B. (author), Xiao, G. (author), Ouwerkerk, P.B.F. (author), Wang, M. (author), Zhu, Z. (author), TNO Kwaliteit van Leven (author)Monosaccharide transporters mediate the membrane transport of a variable range of monosaccharides, which plays a crucial role in sugar distribution throughout the plant. To investigate the significance of monosaccharide transporters for rice (Oryza sativa L.) seed development, cDNA of a new putative monosaccharide transporter gene OsMST4 was...article 2007
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Slob, A. (author), Rijnveld, M. (author)The EU Project AquaTerra generates knowledge about the river-soil-sediment-groundwater system and delivers scientific information of value for river basin management. In this article, the use and ignorance of scientific knowledge in decision making is explored by a theoretical review. We elaborate on the 'two-communities theory', which explains...article 2007
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Hissink, A.M. (author), Krüse, J. (author), Kulig, B.M. (author), Verwei, M. (author), Muijser, H. (author), Salmon, F. (author), Leenheers, L.H. (author), Owen, D.E. (author), Lammers, J.H.C.M. (author), Freidig, A.P. (author), McKee, R.H. (author), TNO Kwaliteit van Leven (author)As part of a project designed to develop a framework for extrapolating acute central nervous system (CNS) effects of hydrocarbon solvents in animals to humans, experimental studies were conducted in rats and human volunteers in which acute CNS effects were measured and toxicokinetic data were collected. A complex hydrocarbon solvent, white...article 2007
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Tielemans, E. (author), Bretveld, R. (author), Schinkel, J. (author), de Wendel van - Joode, B. (author), Kromhout, H. (author), Gerritsen-Ebben, R. (author), Roeleveld, N. (author), Preller, L. (author), TNO Kwaliteit van Leven (author)The aim of this study was to assess exposure to pesticides for a longitudinal epidemiological study on adverse reproduction effects among greenhouse workers. Detailed information on pesticide use among greenhouse workers was obtained on a monthly basis through self-administered questionnaires and subsequent workplace surveys. Questionnaires were...article 2007