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- Verweij, C.A. (author) article 2007
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Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levelsKubben, F.J.G.M. (author), Sier, C.F.M. (author), Schram, M. (author), Witte, T.A.M.C. (author), Veenendaal, R.A. (author), van Duijn, W. (author), Verheijen, J.H. (author), Hanemaaijer, R. (author), Lamers, C.B.H.W. (author), Verspaget, H.W. (author), TNO Kwaliteit van Leven (author)Background: Helicobacter pylori gastritis is recognized as an important pathogenetic factor in peptic ulcer disease and gastric carcinogenesis, and is accompanied by strongly enhanced gastric mucosal matrix metalloproteinase-9 (MMP-9) levels. Aim: This study was performed to investigate whether H. pylori-affected gastric mucosal MMP-2 and MMP-9...article 2007
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- van Bentum, C.A. (author), Geurts, C.P.W. (author), TNO Bouw en Ondergrond (author) article 2007
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van Meer, J.P. (author), Veldhuis, G.J. (author), van Emmerik, M.L. (author), Theunissen, N.C.M. (author), TNO Defensie en Veiligheid (author)Introduction: Due to periodical job rotation within the military, instructional developers are not always experts in their field and are consequently unaware of the types of educational concepts that are available to teach with (Jans & Frazer-Jans, 2004). These observations have led to the construction of a tool named AID (Assistant for...article 2007
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Gibbs, S. (author), van de Sandt, J.J.M. (author), Merk, H.F. (author), Lockley, D.J. (author), Pendlington, R.U. (author), Pease, C.K. (author), TNO Kwaliteit van Leven (author)In this review, we discuss and compare studies of xenobiotic metabolism in both human skin and 3D human skin reconstructs. In comparison to the liver, the skin is a less studied organ in terms of characterising metabolic capability. While the skin forms the major protective barrier to environmental chemical exposure, it is also a potential...article 2007
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Jans, M.P. (author), Proper, K.I. (author), Hildebrandt, V.H. (author), TNO Kwaliteit van Leven (author)Background: Sedentary behavior is an independent risk factor for excess body weight and other health problems. There are no published data on sitting time at work, or how this is related to occupation and sector (branch of business). No published study has shown whether extended sitting at work is compensated for by sitting less during leisure...article 2007
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- Simons, M. (author), Koerhuis, C.L. (author), Valk, P.J.L. (author), van den Oord, M.H.A.H. (author) article 2007
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Sebastian, R. (author), Mooiman, M.A. (author)Zorgpanden zijn soms bij de oplevering al achterhaald. Het Living Building Concept biedt hierop een antwoord. De aannemer krijgt de ruimte om creatieve oplossingen te bedenken voor de hele levensduur van het gebouwarticle 2007
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- Kraan, K. (author), Oeij, P. (author), TNO Kwaliteit van Leven (author) article 2007
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Ruijssenaars, H.J. (author), Sperling, E.M.G.M. (author), Wiegerinck, P.H.G. (author), Brands, F.T.L. (author), Wery, J. (author), de Bont, J.A.M. (author), TNO Kwaliteit van Leven (author)A steroid 15β-hydroxylating whole-cell solvent tolerant biocatalyst was constructed by expressing the Bacillus megaterium steroid hydroxylase CYP106A2 in the solvent tolerant Pseudomonas putida S12. Testosterone hydroxylation was improved by a factor 16 by co-expressing Fer, a putative Fe-S protein from Bacillus subtilis. In addition, the...article 2007
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Smith, A.J.E. (author), TNO Defensie en Veiligheid (author)Many geoscience applications of space‐borne Synthetic Aperture Radar (SAR) imagery require knowledge of the revisit time of the satellite at a location. In this paper, a practical method is presented for computing the revisit times of SAR satellites at any location on Earth. The method is based on the use of maps that give the number of imaging...article 2007
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Wallinga, J. (author), Bos, A.J.J. (author), Dorenbos, P. (author), Murray, A.S. (author), Schokker, J. (author), TNO Bouw en Ondergrond (author)Infrared-stimulated luminescence (IRSL) dating of feldspars has the potential to date deposits beyond the age range of quartz optical (OSL) dating. Successful application of feldspar IRSL dating is, however, often precluded due to anomalous-fading, the tunnelling of electrons from one defect site to another. In this paper we test procedures...article 2007
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Prinz, J.F. (author), de Wijk, R.A. (author), Huntjens, L.A.H. (author), Engelen, L. (author), Polet, I.A. (author), TNO Kwaliteit van Leven (author)It has been generally assumed that fat is detected by its flavour and by its lubrication of the oral mucosa. A recent study reported a correlation of -.99 between perceived temperature of a product and its fat content. This was significantly higher than correlations of sensory scores for fat flavour, mouthfeel, and afterfeel. This suggested a...article 2007
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de Jongh, H.H.J. (author), Janssen, A.M. (author), TNO Kwaliteit van Leven (author)By analyzing swabs from different locations in the mouth (front and middle part of the tongue, cheek and palate) of four subjects after oral processing of dressings, the composition of the retained material was evaluated in time using infrared spectroscopy in an attempt to substantiate the physical origin of differences in afterfeel sensations...article 2007
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van den Hurk, K. (author), van Dommelen, P. (author), van Buuren, S. (author), Verkerk, P.H. (author), HiraSing, R.A. (author), TNO Kwaliteit van Leven (author)Objective: To assess the prevalence of overweight and obesity in children living in the Netherlands and compare the findings with the Third and Fourth National Growth Studies carried out in 1980 and 1997, respectively. Design and methods: Data were obtained from the child health care system. International cut-off points for body mass index (BMI)...article 2007
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Heiri, O. (author), Cremer, H. (author), Engels, S. (author), Hoek, W.Z. (author), Peeters, W. (author), Lotter, A.F. (author), TNO Bouw en Ondergrond (author)Lateglacial environments at Hijkermeer, northwest Netherlands, were reconstructed by means of chironomid, diatom and pollen analyses. Diatom assemblages indicate that Hijkermeer was a shallow, oligo- to mesotrophic lake during this period. Pollen assemblages reflect the typical northwest European Lateglacial vegetation development and provide an...article 2007
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Grothe, M. (author), Kooijman, J. (author), TNO Bouw en Ondergrond (author)One part of the Geographic Information infrastructure that did not receive much attention until recently is embedding dynamic geographic information from sensors. in this article the focus is on the open standards, their opportunities and the open questions of Sensor Weh Enablement (SWE). Meaning can be given to SWE to ensure the accessibility...article 2007
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Kel, J. (author), Oldenampsen, J. (author), Luca, M. (author), Drijfhout, J.W. (author), Koning, F. (author), Nagelkerken, L. (author), TNO Kwaliteit van Leven (author)We have previously shown that immunization with a mannosylated myelin peptide in complete adjuvant induces tolerance instead of disease in experimental autoimmune encephalomyelitis (EAE), a rodent model for multiple sclerosis. In this report we demonstrate that treatment with a soluble mannosylated epitope of proteolipid protein (M-PLP139-151)...article 2007
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van der Meer, V. (author), van Stel, H.F. (author), Detmar, S.B. (author), Otten, W. (author), Sterk, P.J. (author), Sont, J.K. (author), TNO Kwaliteit van Leven (author)Background: Internet and short message service are emerging tools for chronic disease management in adolescents, but few data exist on the barriers to and benefits of internet-based asthma self-management. Our objective was to reveal the barriers and benefits perceived by adolescents with well-controlled and poorly controlled asthma to current...article 2007
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Terpstra, F.G. (author), Rechtman, D.J. (author), Lee, M.L. (author), van Hoeij, K. (author), Berg, H. (author), van Engelenberg, F.A.C. (author), van 't Wout, A.B. (author), TNO Kwaliteit van Leven (author)In the United States, concerns over the transmission of infectious diseases have led to donor human milk generally being subjected to pasteurization prior to distribution and use. The standard method used by North American milk banks is Holder pasteurization (63°C for 30 minutes). The authors undertook an experiment to validate the effects of a...article 2007