Searched for: mods_originInfo_dateIssued_s:"2007"
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Jansen, N.W.D. (author), Roosendaal, G. (author), Bijlsma, J.W.J. (author), de Groot, J. (author), Lafeber, F.P.J.G. (author), TNO Kwaliteit van Leven (author)
Objective. Joint bleeding, or hemarthrosis, leads in time to severe joint damage. This study was carried out to test the in vitro thresholds of exposure time and concentration that lead to irreversible joint damage, to add to the discussion on the usefulness of aspiration of the joint after a hemorrhage. Methods. Explants of healthy human...
article 2007
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de Bruin-Hordijk, T. (author), de Groot, E. (author)
article 2007
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Hille, E.T.M. (author), Weisglas-Kuperus, N. (author), van Goudoever, J.B. (author), Jacobusse, G.W. (author), Ens-Dokkum, M.H. (author), de Groot, L. (author), Wit, J.M. (author), Geven, W.B. (author), Kok, J.H. (author), de Kleine, M.J.K. (author), Kollée, L.A.A. (author), Mulder, A.L.M. (author), van Straaten, H.L.M. (author), de Vries, L.S. (author), van Weissenbruch, M.M. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. Young adults who were born very preterm or with a very low birth weight remain at risk for physical and neurodevelopmental problems and lower academic achievement scores. Data, however, are scarce, hospital based, mostly done in small populations, and need additional confirmation. METHODS. Infants who were born at <32 weeks of...
article 2007
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de Groot, P.C.J. (author), TNO Kwaliteit van Leven (author)
report 2007
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Meulenbelt, I. (author), Kloppenburg, M. (author), Kroon, H.M. (author), Houwing-Duistermaat, J.J. (author), Garnero, P. (author), Hellio-Le Graverand, M.-P. (author), de Groot, J. (author), Slagboom, P.E. (author), TNO Kwaliteit van Leven (author)
Objective: To assess the relationship of biochemical markers and radiographic signs of osteoarthritis (ROA) in the subjects with symptomatic osteoarthritis (OA) at multiple sites of the Genetics osteoARthritis and Progression (GARP) study. Methods: We have measured eight biochemical markers, representing tissue turnover of cartilage, bone,...
article 2007
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Hunter, D.J. (author), Li, J. (author), LaValley, M. (author), Bauer, D.C. (author), Nevitt, M. (author), de Groot, J. (author), Poole, R. (author), Eyre, D. (author), Guermazi, A. (author), Gale, D. (author), Felson, D.T. (author), TNO Kwaliteit van Leven (author)
We used data from a longitudinal observation study to determine whether markers of cartilage turnover could serve as predictors of cartilage loss on magnetic resonance imaging (MRI). We conducted a study of data from the Boston Osteoarthritis of the Knee Study (BOKS), a completed natural history study of knee osteoarthritis (OA). All subjects in...
article 2007
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de Groot, G.J. (author), de Wilde, H.P.J. (author), Weijers, E.P. (author), van der Zee, S.C. (author), Siderius, P. (author), Domburg, N. (author), Segaar, P. (author), Hoogma, R. (author)
Het vervoer van personen en goederen is de afgelopen decennia sterk toegenomen. Dit heeft vooral in stedelijke gebieden een negatieve invloed op de luchtkwaliteit en daardoor ook op de volksgezondheid. Een belangrijke vorm van luchtverontreiniging is fijn stof, aangeduid met PM10. PM10 veroorzaakt aantoonbaar gezondheidsschade (bijv. WHO 1999)...
article 2007
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Broersen, K. (author), Weijers, M. (author), de Groot, J. (author), Hamer, R.J. (author), de Jongh, H.H.J. (author), TNO Kwaliteit van Leven (author)
This study describes how charge modification affects aggregation of ovalbumin, thereby distinguishing the role of conformational and electrostatic stability in the process. Ovalbumin variants were engineered using chemical methylation or succinylation to obtain a range of protein net charge from -1 to -26. Charge modification significantly...
article 2007
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Kamphorst, J.J. (author), van der Heijden, R. (author), de Groot, J. (author), Lafeber, F.P.J.G. (author), Reijmers, T.H. (author), van El, B. (author), Tjaden, U.R. (author), van der Greef, J. (author), Hankemeier, T. (author), TNO Kwaliteit van Leven (author)
Synovial fluid potentially contains markers for early diagnosis and disease progression in degenerative joint diseases such as osteoarthritis. Here, a method is described for profiling endogenous peptides in human synovial fluid, using ultrafiltration, solid-phase extraction, nanoscale liquid chromatography, and high-resolution mass spectrometry...
article 2007
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de Groot, E. (author)
article 2007
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Weeda, M. (author), de Groot, A. (author), Smit, R. (author)
Increasingly people think of how a hydrogen energy supply system would look like, and how to build and end up at such a system. This paper presents the work on modelling and simulation of current ideas among Dutch hydrogen stakeholders for a transition towards the widespread use of a hydrogen energy. Based mainly on economic considerations, the...
article 2007
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de Mos, M. (author), van El, B. (author), de Groot, J. (author), Jahr, H. (author), van Schie, H.T.M. (author), van Arkel, E.R. (author), Tol, H. (author), Heijboer, R. (author), van Osch, G.J.V.M. (author), Verhaar, J.A.N. (author), TNO Kwaliteit van Leven (author)
Background: Understanding biochemical and structural changes of the extracellular matrix in Achilles tendinosis might be important for developing mechanism-based therapies. Hypothesis: In Achilles tendinosis, changes occur in biochemical composition and collagen turnover rate. Study Design: Descriptive laboratory study. Methods: From 10 patients...
article 2007
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de Groot, J. (author), Kosters, H.A. (author), de Jongh, H.H.J. (author), TNO Kwaliteit van Leven (author)
To study the influence of the carbohydrate-moiety of ovalbumin on the formation of the heat-stable conformer S-ovalbumin, ovalbumin is deglycosylated with PNGase-F under native conditions. Although the enzymatic deglycosylation procedure resulted in a complete loss of the ability to bind to Concavalin A column-material, only in about 50% the...
article 2007
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Steenvoorden, M.M.C. (author), Toes, R.E.M. (author), Ronday, H.K. (author), Huizinga, T.W.J. (author), de Groot, J. (author), TNO Kwaliteit van Leven (author)
Ligands for the receptor for advanced glycation endproducts (RAGE) are increased in RA synovial fluid (SF), serum and synovium. Since RAGE is present on fibroblast-like synoviocytes (FLS), the present study investigates whether the RAGE ligands HMGB-1 and AGEs are able to stimulate the characteristic, pathological invasive behaviour of these...
article 2007
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Kamphuis, I.G. (author), Kester, J.C.P. (author), van Elkhuizen, B. (author), de Groot, E. (author), Energieonderzoek Centrum Nederland (author)
n.v.t.
article 2007
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Steenvoorden, M.M.C. (author), Bank, R.A. (author), Ronday, H.K. (author), Toes, R.E.M. (author), Huizinga, T.W.J. (author), de Groot, J. (author), TNO Kwaliteit van Leven (author)
Objective: In vitro models for joint diseases often focus on a single cell type, such as chondrocytes in osteoarthritis (OA) or fibroblast-like synoviocytes (synoviocytes) in rheumatoid arthritis (RA). However, these joint diseases affect the whole joint and interaction between chondrocytes and synoviocytes may play an important role in disease...
article 2007
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de Groot, E. (author)
article 2007
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de Groot, E.H. (author), Knoop, M. (author), TNO Bouw (author)
In the Netherlands, 76%o of the working population sometimes or regularly works between midnight and 6 a.m. This percentage is comparable to those of other countries. Two of the most common and harmful problems associated with shift work are reduced quality of sleep and a reduced alertness while at work. Photobiological light can be used to...
conference paper 2007
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de Groot, E. (author), TNO Bouw (author)
conference paper 2007
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Elkhuizen, P.A. (author), de Groot, E.H. (author), TNO Bouw (author)
Met het aanbrengen van verbeteringen in de regelingen is grote vooruitgang te boeken, op gebied van zowel het gebouwcomfort als het energiegebruik. Het betreden van de gebruiker bij de regeling, via gebruikersadaptieve en -educatieve regelingen, is hiervoor essentieel. Uit het project 'Demand Side Management achter de meter van ECN en TNO blijkt...
article 2007
Searched for: mods_originInfo_dateIssued_s:"2007"
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