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Käppler, W.D. (author), Godthelp, J. (author), Instituut voor Zintuigfysiologie TNO (author)Open and closed-loop test procedures and subjective rating procedures on vehicle handling properties were developed and used in two experiments with an instrumented car. In the first experiment, the influences of tyre pressure variations on vehicle handling were determined in open-loop tests, i.e. steady-state curve driving, step steering inputs...article 1988
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- Bergmeijer, P. (author), Oversloot, H.P. (author), Technisch Physische Dienst TNO - TH (author) report 1988
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- Blonk, J.C. (author), Technisch Physische Dienst TNO - TH (author) article 1988
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Struik, L.C.E. (author), Centrum voor Polymere Materialen TNO Kunststoffen en Rubber Instituut TNO (author)This paper deals with the volume relaxation and simultaneous changes in mechanical properties that occur after complicated thermal histories. The histories were chosen such that, at the final measuring temperature, the specific volume v passes through a maximum with increasing time. It is shown that, for polystyrene, poly(vinyl chloride) and...article 1988
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- Hekman, P. (author), Rietveld, E.C. (author), Weseman, J.M. (author), Instituut voor Landbouwkundig Onderzoek en Biochemische Produkten TNO (author) article 1988
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Hooisma, J. (author), Twisk, D.A.M. (author), Platalla, S. (author), Muijser, H. (author), Kulig, B.M. (author), Medisch Biologisch Laboratorium TNO (author)The performance characteristics of 4 computerized psychological tests were studied using alcohol as a model compound. Subjects received alcohol (0.5 ml/kg) or placebo in a cross-over design and performance was assessed using the Simple Reaction Time test, the Switching Attention test, the Hand/Eye Coordination test and the Color-Word Vigilance...article 1988
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de Bruin, P.A.F. (author), Griffioen, G. (author), Verspaget, H.W. (author), Verhijend, J.H. (author), Dooijewaard, G. (author), van den Ingh, H.F. (author), Lamers, B.H.W. (author), Gezondheidsorganisatie TNO Gaubius instituut TNO (author)Plasminoceli activator (PA) activity, in particular urokinase (u-PA), has been shown to be markedly increased in adenocarcinomas of the colon. Adenomatous polyps were found to be intermediate in their PA activity to normal mucosa and adenocarcinomas. In the present study we evaluated the PA profile in relation to malignancy parameters of the...article 1988
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Janssen, W.H. (author), Tenkink, E. (author), Instituut voor Zintuigfysiologie TNO (author)Risk-taking behavior by drivers is put within the context of a general model of utility maximization by speed choice. It is shown that so-called "risk homeostasis" is possible only under very restrictive conditions. Under more general conditions, risk compensation can occur; that is, the safety effects expected from engineering measures will be...article 1988
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- Frants, R.R. (author), Smit, M. (author), van der Kooij-Meijs, E. (author), de Knijff, P. (author), Gevers Leuven, J.A. (author), Havekes, L.M. (author), Gaubius Instituut TNO (author) bookPart 1988
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Gizdulich, P. (author), Wesseling, K.H. (author), TNO Biomedical Instrumentation (author)Pressure-volume (p-V) relationships of a segment of the forearm circulation have been measured in nine male healthy subjects. Forearm volume was measured using electrical impedance plethysmography, arterial transmural pressure by subtracting mean arterial pressure measured contralaterally in a finger from the pressure in a cuff placed over the...article 1988
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van Ruiten, C.J.M. (author), Technisch Physische Dienst TNO - TH (author)Squeal noise is very often the most disturbing noise source of railway systems in older cities. At present the effect of measures to reduce or to eliminate squeal noise cannot be predicted and seems to be influenced by a large number of dependent parameters. On the basis of the measurement results of a research project in three cities with seven...article 1988
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- Heemskerk, A.H. (author), Prins Maurits Laboratorium TNO (author) conference paper 1988
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Hooftman, R.N. (author), Kuper, C.F. (author), Appelman, L.M. (author), Hoofdgroep Maatschappelijke Technologie TNO (author)The sensitivity of different parameters for the determination of lung injury caused by nitrogen dioxide (NO2) was investigated. Male rats were exposed to concentrations of 0, 4, 10 or 25 ppm NO2 for 6 h/day, for 7, 14 or 21 days. Histopathology of the nasal cavity, larynx, trachea and lungs was compared with the changes in macrophage function...article 1988
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Bot, F.J. (author), Dorssers, L. (author), Wagemaker, G. (author), Loewenberg, B. (author), Gaubius Instituut TNO (author)Recently, human multi-CSF was obtained by molecular cloning. In the present study, the effects of multi-CSF in vitro were investigated by comparative culture of whole bone marrow or progenitor cells obtained by sorting the cell fraction that binds the monoclonal antibody (MoAb) B13C5 (CD 34). Multi-CSF stimulated erythroid (BFU-E),...article 1988
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Zwart, A. (author), Woutersen, R.A. (author), Wilmer, J.W.G.M. (author), Spit, B.J. (author), Feron, V.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)To study in detail possible effects of low concentrations of formaldehyde on the nasal epithelium, Wistar rats were exposed to 0, 0.3, 1 and 3 ppm formaldehyde vapour for 6 h/day, 5 days/week during 3 days or 13 weeks, using in vivo [3H]thymidine labeling for cell proliferation studies, and light and electron microscopy for detecting...article 1988
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- Nicolaas, H.J. (author), Technisch Physische Dienst TNO - TH (author) article 1988
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- van Tongeren, P.J. (author), Lemaire, A.D. (author), Technisch Physische Dienst TNO - TH (author) article 1988
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- de Vries, U. (author), Sluimer, P. (author), Bloksma, A.H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author) conference paper 1988
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de Groot, A.P. (author), Feron, V.J. (author), Immel, H.R. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)In previous studies we observed an increased incidence of hyperplasia in the epithelium of the urinary bladder of rats fed cereal-based stock diet supplemented with 6% monosodium glutamate (MSG) for 3 months. Hyperplasia was not enhanced, however, when 6% MSG was fed in a purified casein diet. Further studies have been conducted to identify the...article 1988
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- Kolkert, W.J. (author), Prins Maurits Laboratorium TNO (author) conference paper 1988