Searched for: author%3A%22van+der+Kooij%2C+A.J.%22
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van Wietmarschen, H.A. (author), Dai, W. (author), van der Kooij, A.J. (author), Reijmers, T.H. (author), Schroën, Y. (author), Wang, M. (author), Xu, Z. (author), Wang, X. (author), Kong, H. (author), Xu, G. (author), Hankemeier, T. (author), Meulman, J.J. (author), van der Greef, J. (author)
Objective: The aim is to characterize subgroups or phenotypes of rheumatoid arthritis (RA) patients using a systems biology approach. The discovery of subtypes of rheumatoid arthritis patients is an essential research area for the improvement of response to therapy and the development of personalized medicine strategies. Methods: In this study,...
article 2012
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van Wietmarschen, H.A. (author), Reijmers, T.H. (author), van der Kooij, A.J. (author), Schroën, J. (author), Wei, H. (author), Hankemeier, T. (author), Meulman, J.J. (author), van der Greef, J. (author)
Background: The future of personalized medicine depends on advanced diagnostic tools to characterize responders and non-responders to treatment. Systems diagnosis is a new approach which aims to capture a large amount of symptom information from patients to characterize relevant sub-groups. Methodology: 49 patients with a rheumatic disease were...
article 2011
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Manisera, M. (author), van der Kooij, A.J. (author), Dusseldorp, E. (author)
The component structure of 14 Likert-type items measuring different aspects of job satisfaction was investigated using nonlinear Principal Components Analysis (NLPCA). NLPCA allows for analyzing these items at an ordinal or interval level. The participants were 2066 workers from five types of social service organizations. Our results suggest...
article 2010