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Instituut voor Experimentele Gerontologie TNO (author), Radl, J. (author), Punt, Y.A. (author), van den Enden-Vieveen, M.H.M. (author), Bentvelzen, P.A.J. (author), Bakkus, M.H.C. (author), van den Akker T., W. (author), Benner, R. (author)
Consistent chromosomal translocations involving the c-myc cellular oncogene and one of the three immunoglobulin loci are typical for human Burkitt's lymphoma, induced mouse plasmacytoma (MPC) and spontaneously arising rat immunocytoma (RIC). Another plasma cell malignancy, multiple myeloma (MM), arising spontaneously in the ageing C57BL/KaLwRij...
article 1990
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Radl, J. (author), Croese, J.W. (author), Zurcher, C. (author), van den Enden-Vieveen, M.H.M. (author), de Leeuw, A.M. (author), Instituut voor Experimentele Gerontologie TNO (author)
Animal models of spontaneous and induced plasmacytomas in some inbred strains of mice have proven to be useful tools for different studies on tumorigenesis and immunoregulation. Their wide applicability and the fact that after their intravenous transplantation, the recipient mice developed bone lesions, led in some instances to an incorrect use...
article 1988