Searched for: author%3A%22van+den+Broek%2C+T.J.%22
(1 - 20 of 22)

Pages

document
Vals-Delgado, C. (author), Alcala-Diaz, J.F. (author), Molina-Abril, H. (author), Roncero-Ramos, I. (author), Caspers, M.P.M. (author), Schuren, F.H.J. (author), van den Broek, T.J. (author), Luque, R. (author), Perez-Martinez, P. (author), Katsiki, N. (author), Delgado-Lista, J. (author), Ordovas, J.M. (author), van Ommen, B. (author), Camargo, A (author), Lopez-Miranda, J. (author)
Introduction: A distinctive gut microbiome have been linked to type 2 diabetes mellitus (T2DM). Objectives: We aimed to evaluate whether gut microbiota composition, in addition to clinical biomarkers, could improve the prediction of new incident cases of diabetes in patients with coronary heart disease. Methods: All the patients from the...
article 2022
document
van Mierlo, M.M.F. (author), Pardo, L.M. (author), Fieten, K.B. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), van Geel, M. (author), Pasmans, S.G.M.A. (author)
Background: Interactions between the skin barrier, immune system, and microbiome underlie the development of atopic dermatitis (AD). Objective: To investigate the skin and nasal microbiome in relation to filaggrin gene (FLG) mutations. Methods: A cross-sectional study including 77 children with difficult-to-treat AD. The entire encoding region...
article 2022
document
Rafiq, R. (author), Aleva, F.E. (author), Schrumpf, J.A. (author), Daniels, J.M. (author), Bet, P.M. (author), Boersma, W.G. (author), Bresser, P. (author), Spanbroek, M. (author), Lips, P. (author), van den Broek, T.J. (author), Keijser, B.J.F. (author), van der Ven, J.A.M. (author), Hiemstra, P.S. (author), den Heijer, M. (author), de Jongh, R.T. (author), PRECOVID-study group, (author)
Background. Vitamin D deficiency is frequently found in patients with chronic obstructive pulmonary disease (COPD). Vitamin D has antimicrobial, anti-inflammatory, and immunomodulatory effects. Therefore, supplementation may prevent COPD exacerbations, particularly in deficient patients. Objectives. We aimed to assess the effect of vitamin D...
article 2022
document
van den Brink, W.J. (author), van den Broek, T.J. (author), Palmisano, S. (author), Wopereis, S. (author), de Hoogh, I.M. (author)
Digital health technologies may support the management and prevention of disease through personalized lifestyle interventions. Wearables and smartphones are increasingly used to continuously monitor health and disease in everyday life, targeting health maintenance. Here, we aim to demonstrate the potential of wearables and smartphones to (1)...
article 2022
document
Wiese, M. (author), Schuren, F.H.J. (author), Smits, W.K. (author), Kuijpers, E.J. (author), Ouwens, A. (author), Heerikhuisen, M. (author), Vigsnaes, L. (author), van den Broek, T.J. (author), de Boer, P. (author), Montijn, R.C. (author), Vossen, J.M.B.M. (author)
Background: Clostridioides difficile is a Gram-positive anaerobic bacterium that can produce the toxins TcdA and/or TcdB and is considered an opportunistic pathogen. C. difficile is mainly transmitted as endospores, which germinate to produce the pathogenic vegetative cells under suitable conditions in the gut. To efficiently screen novel...
article 2022
document
de Hoogh, I.M. (author), Winters, B.L. (author), Nieman, K.M. (author), Bijlsma, S. (author), Krone, T. (author), van den Broek, T.J. (author), Anderson, B.D. (author), Caspers, M.P.M. (author), Anthony, J.C. (author), Wopereis, S. (author)
Personalized nutrition may be more effective in changing lifestyle behaviors compared to population-based guidelines. This single-arm exploratory study evaluated the impact of a 10-week personalized systems nutrition (PSN) program on lifestyle behavior and health outcomes. Healthy men and women (n = 82) completed the trial. Individuals were...
article 2021
document
Kim, Y. (author), Kim, Y. (author), Hwang, J. (author), van den Broek, T.J. (author), Oh, B. (author), Kim, J.Y. (author), Wopereis, S. (author), Bouwman, J. (author), Kwon, O. (author)
Oxidative stress aggravates the progression of lifestyle-related chronic diseases. However, knowledge and practices that enable quantifying oxidative stress are still lacking. Here, we performed a proof-of-concept study to predict the oxidative stress status in a healthy population using retrospective cohort data from Boramae medical center in...
article 2021
document
Fluitman, K.S. (author), van den Broek, T.J. (author), Nieuwdorp, M. (author), Visser, M. (author), IJzerman, R.G. (author), Keijser, B.J.F. (author)
Poor taste and smell function are widely thought to contribute to the development of poor appetite and undernutrition in older adults. It has been hypothesized that the oral microbiota play a role as well, but evidence is scarce. In a cross-sectional cohort of 356 older adults, we performed taste and smell tests, collected anthropometric...
article 2021
document
Wacoo, A.P. (author), Atukunda, P. (author), Muhoozi, G. (author), Braster, M. (author), Wagner, M. (author), van den Broek, T.J. (author), Sybesma, W. (author), Westerberg, A.C. (author), Iversen, P.O (author), Kort, R. (author)
article 2020
document
Kelly, J.M. (author), Matuszek, G. (author), van den Broek, T.J. (author), Huggins, G.S. (author), Smith, C.E. (author), Ordovas, J.M. (author), Wopereis, S. (author), Booth, S.L. (author)
Inconsistent associations between lipids and circulating markers of fat-soluble vitamin and carotenoid status have been reported. The aim of this hypothesis-generating study was to examine the contribution of the LC-MS-based lipidome, characterized by lipid class, carbon count, and the number of unsaturated bonds, to the interindividual...
article 2020
document
Hoevenaars, F.P.M. (author), Berendsen, C.M.M. (author), Pasman, W.J. (author), van den Broek, T.J. (author), Barrat, E. (author), de Hoogh, I.M. (author), Wopereis, S. (author)
In public health initiatives, generic nutrition advice (GNA) from national guidelines has a limited effect on food-intake improvement. Personalized nutrition advice (PNA) may enable dietary behavior change. A monocentric, randomized, parallel, controlled clinical trial was performed in males (n = 55) and females (n = 100) aged 25 to 70 years....
article 2020
document
Tott, J.E.E. (author), Pardo, L.M. (author), Fieten, K.B. (author), Vos, M.C. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), Pasmans, S.G.M.A. (author)
Background: Alterations of the skin microbiome have been associated with atopic dermatitis (AD) and its severity. The nasal microbiome in relation to AD severity is less well studied. Objectives: We aimed to characterize the nasal and skin microbiomes in children with AD in relation to disease severity. In addition, we explored the differences...
article 2019
document
van Mierlo, M.M.F. (author), Totté, J.E.E. (author), Fieten, K.B. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), Pardo, L.M. (author), Pasmans, S.G.M.A. (author)
Background: The skin microbiome, characterized by an overgrowth of Staphylococcus aureus, plays an important role in the pathogenesis of atopic dermatitis (AD). Multidisciplinary treatment in alpine climate is known for its positive effect on disease severity in children with AD and can result in a different immune response compared with...
article 2019
document
Atukunda, P. (author), Muhoozi, G.K.M. (author), van den Broek, T.J. (author), Kort, R. (author), Diep, L.M. (author), Kaaya, A.N. (author), Iversen, P.O. (author), Westerberg, A.C. (author)
Background Undernutrition impairs child development outcomes and growth. In this follow-up study of an open cluster-randomized intervention trial we examined the effects of an education package delivered to mothers in rural Uganda on their children's development, growth and gut microbiota at 36 months of age. Methods The parental trial included...
article 2019
document
Keijser, B.J.F. (author), Agamennone, V. (author), van den Broek, T.J. (author), Caspers, M. (author), van de Braak, A. (author), Bomers, R. (author), Havekes, M. (author), Schoen, E. (author), van Baak, M. (author), Mioch, D. (author), Bomers, L. (author), Montijn, R.C. (author)
Background: Antibiotic therapy is commonly used in animal agriculture. Antibiotics excreted by the animals can contaminate farming environments, resulting in long term exposure of animals to sub-inhibitory levels of antibiotics. Little is known on the effect of this exposure on antibiotic resistance. In this study, we aimed to investigate the...
article 2019
document
van Bilsen, J.H.M. (author), Verschuren, L. (author), Wagenaar, L. (author), Vonk, M.M. (author), van Esch, B.C.A.M. (author), Knippels, L.M.J. (author), Garssen, J. (author), Smit, J.J. (author), Pieters, R.H.H. (author), van den Broek, T.J. (author)
Background: Oral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, concerns with regards to safety and long-term efficacy of OIT remain. There is a need to identify biomarkers that predict, monitor and/or evaluate the effects of OIT. Here we present a method to select candidate biomarkers for...
article 2019
document
Meijerink, M. (author), van den Broek, T.J. (author), Dulos, R. (author), Garthoff, J. (author), Knippels, L. (author), Knipping, K. (author), Harthoorn, L. (author), Houben, G. (author), Verschuren, L. (author), van Bilsen, J. (author)
To assess the safety and efficacy of oral immune interventions, it is important and required by regulation to assess the impact of those interventions not only on the immune system, but also on other organs such as the gut as the porte d'entrée. Despite clear indications that the immune system interacts with several physiological functions of...
article 2019
document
Keijser, B.J.F. (author), van den Broek, T.J. (author), Slot, D.E. (author), van Twillert, L. (author), Kool, J. (author), Thabuis, C. (author), Ossendrijver, M. (author), van der Weijden, F.A. (author), Montijn, R.C. (author)
Background: The oral cavity harbors a complex microbial ecosystem, intimately related to oral health and disease. The use of polyol-sweetened gum is believed to benefit oral health through stimulation of salivary flow and impacting oral pathogenic bacteria. Maltitol is often used as sweetener in food products. This study aimed to establish the...
article 2018
document
Fiamoncini, J. (author), Yiorkas, A.M. (author), Gedrich, K. (author), Rundle, M. (author), Alsters, S.I. (author), Roeselers, G. (author), van den Broek, T.J. (author), Clavel, T. (author), Lagkouvardos, I. (author), Wopereis, S. (author), Frost, G. (author), van Ommen, B. (author), Blakemore, A.I. (author), Daniel, H. (author)
Bile acids (BA) are signaling molecules with a wide range of biological effects, also identified among the most responsive plasma metabolites in the postprandial state. We here describe this response to different dietary challenges and report on key determinants linked to its interindividual variability. Healthy men and women (n = 72, 62 ± 8 yr,...
article 2017
document
van den Broek, T.J. (author), Kremer, B.H.A. (author), marcondes Rezende, M. (author), Hoevenaars, F.P.M. (author), Weber, P. (author), Hoeller, U. (author), van Ommen, B. (author), Wopereis, S. (author)
Background. Vitamins and carotenoids are key micronutrients facilitating the maintenance of health, as evidenced by the increased risk of disease with low intake. Optimal phenotypic flexibility, i.e., the ability to respond to a physiological challenge, is an essential indicator of health status. Therefore, health can be measured by applying a...
article 2017
Searched for: author%3A%22van+den+Broek%2C+T.J.%22
(1 - 20 of 22)

Pages