Searched for: author%3A%22van+de+Sandt%2C+J.J.M.%22
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van de Sandt, J.J.M. (author), Feron, V.J. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
With rapidly increasing knowledge of toxicological processes, the scientific value and relevance of toxicity studies for risk assessment must be re-evaluated. In this paper, it is proposed that the rigid risk evaluation currently required should be replaced by a more flexible, case-by-case approach, in order to increase the relevance of each...
article 1996
document
Blaauboer, B.J. (author), Bayliss, M.K. (author), Castell, J.V. (author), Evelo, C.T.A. (author), Frazier, J.M. (author), Groen, K. (author), G├╝lden, M. (author), Guillouzo, A. (author), Hissink, A.M. (author), Houston, J.B. (author), Johanson, G. (author), de Jongh, J. (author), Kedderis, G.L. (author), Reinhardt, C.A. (author), van de Sandt, J.J.M. (author), Semino, G. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
article 1996
document
Elliott, G.R. (author), de Lange, J. (author), van de Sandt, J.J.M. (author), Rutten, A.A.J.J.L. (author), Meuling, W.J.A. (author), Opdam, J.J.G. (author), Bruijnzeel, P.L.B. (author), TNO Voeding (author)
bookPart 1996
document
van de Sandt, J.J.M. (author), Rutten, A.A.J.J.L. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
The toxicity of well known irritants was investigated in rabbit and human skin organ cultures. Test chemicals were selected from various categories of irritants and included both water-soluble and water-insoluble compounds. Using a highly standardized protocol, test chemicals were applied topically at concentrations relevant to the in vivo...
article 1995
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van de Sandt, J.J.M. (author), Maas, W.J.M. (author), Doornink, P.C. (author), Rutten, A.A.J.J.L. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
In vitro techniques make a major contribution to the development of alternatives to the in vivo 'Draize' skin irritation test, and the development of sensitive and generally applicable in vitro endpoints of cutaneous toxicity is an area of intensive research. To investigate in vitro characteristics of cutaneous irritation, skin explants of...
article 1995
document
van de Sandt, J.J.M. (author), Rutten, A.A.J.J.L. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
article 1995
document
van de Sandt, J.J.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
bookPart 1995
document
van de Sandt, J.J.M. (author), Bos, T.A. (author), Rutten, A.A.J.J.L. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
Epidermal cell proliferation and differentiation were investigated in vitro after exposure to the anionic surfactant sodium dodecyl sulfate (SDS). Human skin organ cultures were exposed topically to various concentrations of SDS for 22 h, after which the irritant was removed. Cell proliferation was measured immunohistochemically by incorporation...
article 1995
document
van Nesselrooij, J.H.J. (author), Kuper, C.F. (author), Feron, V.J. (author), van den Berg, K.J. (author), Hoogendijk, E.M.G. (author), Kulig, B.M. (author), Cassee, F.R. (author), Groten, J.P. (author), Roggeband, R. (author), van den Berg, P.T.M. (author), Steenwinkel, M-J.S.T. (author), van Delft, J.H.M. (author), Baan, R.A. (author), Rompelberg, J.J.M. (author), van den Heuvel, P.D. (author), Bruijntjes-Rozier, T.C.D.M. (author), Leeman, R.R. (author), Verhagen, H. (author), van de Sandt, J.J.M. (author), Bos, T.A. (author), Rutten, A.A.J.J.L. (author), Sloot, W.N. (author), Gramsbergen, J.B.P. (author), Velthuis-te Wierik, E.J.M. (author), de Vogel, N. (author), Wolterbeek, A.P.M. (author), Schoevers, E.J. (author), van Moorsel, C.J.A. (author)
article 1994
document
TNO Voeding (author), van de Sandt, J.J.M. (author)
doctoral thesis 1994
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