Searched for: author:"van Tol, A."
(1 - 19 of 19)
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Henneman, P. (author), Schaap, F.G. (author), Havekes, L.M. (author), Rensen, P.C.N. (author), Frants, R.R. (author), van Tol, A. (author), Hattori, H. (author), Smelt, A.H.M. (author), van Dijk, K.W. (author), TNO Kwaliteit van Leven (author)
Objective: The recently discovered apoAV is hypothesized to affect triglyceride metabolism by stimulating the lipolysis of triglycerides in VLDL and chylomicrons. We set out to determine the association between increased serum TG levels, plasma apoAV levels, and polymorphism of the APOA5 gene, with specific emphasis on the APOA5 S19W variation....
article 2007
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Hendriks, H.F. (author), van Tol, A. (author), TNO Kwaliteit van Leven (author)
Alcohol consumption affects overall mortality. Light to moderate alcohol consumption reduces the risk of coronary heart disease; epidemiological, physiological and genetic data show a causal relationship. Light to moderate drinking is also associated with a reduced risk of other vascular diseases and probably of type 2 diabetes. Mortality and...
bookPart 2005
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Beulens, J.W.J. (author), Sierksma, A. (author), van Tol, A. (author), Fournier, N. (author), van Gent, T. (author), Paul, J.L. (author), Hendriks, H.F.J. (author), TNO Voeding (author)
Moderate alcohol consumption increases HDL cholesterol, which is involved in reverse cholesterol transport (RCT). The aim of this study was to investigate the effect of moderate alcohol consumption on cholesterol efflux, using J774 mouse macrophages and Fu5AH cells, and on other parameters in the RCT pathway. Twenty-three healthy men (45-65...
article 2004
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Sierksma, A. (author), Vermunt, S.H.F. (author), Lankhuizen, I.M. (author), van der Gaag, M.S. (author), Scheek, L.M. (author), Grobbee, D.E. (author), van Tol, A. (author), Hendriks, H.F.J. (author), TNO Voeding (author)
Background: Alcohol consumption is associated with increased high-density lipoprotein (HDL) cholesterol levels. One of the main antiatherogenic functions of HDL is reverse cholesterol transport. Three early steps of reverse cholesterol transport are (1) cellular cholesterol efflux, (2) plasma cholesterol esterification (EST), and (3) cholesteryl...
article 2004
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Post, S.M. (author), de Crom, R. (author), van Haperen, R. (author), van Tol, A. (author), Princen, H.M.G. (author), Gaubius Instituut TNO (author)
Objective - HDL plays a key role in protection against development of atherosclerosis by promoting reverse cholesterol transport from peripheral tissues to the liver for secretion into bile. Phospholipid transfer protein (PLTP) promotes the transfer of phospholipids between lipoproteins and modulates HDL size and composition, thereby having a...
article 2003
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Sierksma, A. (author), van der Gaag, M.S. (author), van Tol, A. (author), James, R.W. (author), Hendriks, H.F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Background: The inverse association between moderate drinking and coronary heart disease mortality is well established. This study was performed to investigate the kinetics of the alcohol-induced increases in apo A-1, HDL cholesterol, and paraoxonase (PON) activity, as well as to study whether the alcohol-induced increases in PON activity differ...
article 2002
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Vermunt, S.H.F. (author), Sierksma, A. (author), van der Gaag, M.S. (author), van Tol, A. (author), Hendriks, H.F.J. (author), TNO Voeding (author)
article 2001
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Vermunt, S.H.F. (author), Sierksma, A. (author), van der Gaag, M.S. (author), van Tol, A. (author), Hendriks, H.F.J. (author), TNO Voeding (author)
article 2001
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van Tol, A. (author), Hendriks, H.F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Light to moderate alcohol consumption is associated with a reduced risk of coronary heart disease, as well as ischaemic stroke and possibly type 2 diabetes. Epidemiological and physiological data are in favour of a causal relationship. Proposed protective mechanisms include the stimulation of HDL-mediated processes such as reverse cholesterol...
article 2001
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van der Gaag, M.S. (author), van Tol, A. (author), Vermunt, S.H.F. (author), Scheek, L.M. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Alcohol consumption is associated with increased HDL cholesterol levels, which may indicate stimulated reverse cholesterol transport. The mechanism is, however, not known. The aim of this study was to evaluate the effects of alcohol consumption on the first two steps of the reverse cholesterol pathway: cellular cholesterol efflux and plasma...
article 2001
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van der Gaag, M.S. (author), Sierksma, A. (author), Schaafsma, G. (author), van Tol, A. (author), Geelhoed-Mieras, T. (author), Bakker, M. (author), Hendriks, H.F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
article 2000
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van der Gaag, M.S. (author), van Tol, A. (author), Scheek, L.M. (author), James, R.W. (author), Urgert, R. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Moderate alcohol consumption is associated with a reduced risk of coronary heart disease. Part of this inverse association may be explained by its effects on HDL. Paraoxonase, an HDL-associated enzyme, has been suggested to protect against LDL oxidation. We examined the effects of moderate consumption of red wine, beer and spirits in comparison...
article 1999
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van der Gaag, M.S. (author), van Tol, A. (author), Scheek, L.M. (author), James, R.W. (author), Urgert, R. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author)
article 1999
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van Tol, A. (author), van der Gaag, M.S. (author), Scheek, L.M. (author), van Gent, T. (author), Hendriks, H.F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
We measured the effects of consumption of moderate amounts of beer, wine or spirits with evening dinner on plasma LDL and HDL levels as well as composition in 11 healthy middle-aged men. Forty grams of alcohol were consumed daily with dinner for a period of 3 weeks. Mineral water was used as a negative control. Dinner was served at 6 pm and...
article 1998
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Hendriks, H.F.J. (author), Veenstra, J. (author), van Tol, A. (author), Groener, J.E.M. (author), Schaafsma, G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Moderate alcohol consumption is associated with a reduced risk of coronary heart disease. In this study, postprandial changes in plasma lipids, high-density lipoprotein (HDL) composition and cholesteryl ester transfer protein (CETP) and lecithin: cholesterol acyltransferase (LCAT) activity levels were investigated in response to moderate alcohol...
article 1998
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van Tol, A. (author), Groener, J.E.M. (author), Scheek, L.M. (author), van Gent, T. (author), Veenstra, J. (author), van de Pol, H. (author), Hendriks, H.F.J. (author), Schaafsma, G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
article 1995
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Zhao, S.P. (author), Smelt, A.H. (author), van den Maagdenberg, A.M. (author), van Tol, A. (author), Vroom, T.F. (author), Gevers Leuven, J.A. (author), Frants, R.R. (author), Havekes, L.M. (author), van der Laarse, A. (author), van 't Hooft, F.M. (author), TNO Preventie en Gezondheid (author)
Using a density-gradient ultracentrifugation technique, we analyzed in detail the plasma lipoprotein profiles of 18 patients with familial dysbetalipoproteinemia (FD) who had apolipoprotein (apo) E2(Arg158-->Cys) homozygosity (the E2-158 variant, n = 6), apoE3-Leiden heterozygosity (the E3-Leiden variant, n = 6), or apoE2(Lys146-->Gln)...
article 1994
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Uiterwaal, C.S.P.M. (author), Grobbee, D.E. (author), Witteman, J.C.M. (author), van Stiphout, W.A.H.J. (author), Krauss, X.H. (author), Havekes, L.M. (author), de Bruijn, A.M. (author), van Tol, A. (author), Hofman, A. (author), TNO Preventie en Gezondheid (author)
Setting: Coronary angiography departments of four central general hospitals in the Netherlands. Patients: 80 sons (mean age, 24.8 years) of men with severe coronary artery disease and 55 sons (mean age, 23.2 years) of controls. Measurements: Postprandial levels of serum triglycerides, retinyl palmitate, and total cholesterol were measured during...
article 1994
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Groot, P.H.E. (author), van Stiphout, W.A. (author), Krauss, X.H. (author), Jansen, H. (author), van Tol, A. (author), van Ramshorst, E. (author), Chin-On, S. (author), Hofman, A. (author), Cresswell, S.R. (author), Havekes, L. (author), Gezondheidsorganisatie TNO Gaubius instituut TNO (author)
article 1991
Searched for: author:"van Tol, A."
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