Searched for: author:"van Hemmen, J.J."
(1 - 20 of 107)

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van Hemmen, J.J. (author), Marquart, H. (author), TNO Kwaliteit van Leven (author)
article 2009
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van Hemmen, J.J. (author), Gerritsen-Ebben, R. (author), TNO Kwaliteit van Leven (author)
The approaches that are indicated in the various guidance documents for the assessment of human exposure for chemicals and biocides are summarised. This reflects the TNsG (Technical notes for Guidance) version 2: human exposure assessment for biocidal products (1) under the BPD (Biocidal Products Directive) (2), and the results of the REACH ...
article 2008
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van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
article 2008
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Meuling, W.J.A. (author), van de Sandt, J.J.M. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
article 2007
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Gerritsen-Ebben, R.M.G. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
Directive 98/8/EC(1) concerns EU harmonisation of placing biocidal products on the market. In the present short paper the preliminary results of an ongoing project are presented in which step by step guidance on human exposure assessment with worked examples is developed. For all 23 biocidal product types a unified approach is developed to be...
article 2007
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Gerritsen-Ebben, M.G. (author), Brouwer, D.H. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
Regulatory authorities in North America, Europe and Australia use different approaches for the estimation of exposure reduction effectiveness of personal protective equipment (PPE) in registration processes of agrochemical pesticides. TNO has investigated current views and facts for the use of default values and set up a discussion paper which...
article 2007
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Money, C.D. (author), van Hemmen, J.J. (author), Vermeire, T.G. (author), TNO Kwaliteit van Leven (author)
The primary process established by the European Commission to address the science needed to define key REACH concepts and to help rationally implement REACH's ambitions is enshrined in a series of activities known as the REACH Implementation Projects (RIPs). These are projects that aim to define the methodology that could be used, and present...
article 2007
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Gerritsen-Ebben, M.G.R. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
article 2007
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van de Sandt, J.J.M. (author), Dellarco, M. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
Exposure scenarios form an essential basis for chemical risk assessment reports under the new EU chemicals regulation REACH (Registration, Evaluation, Authorisation and restriction of Chemicals). In case the dermal route of exposure is predominant, information on both exposure and dermal bioavailability is necessary for a proper risk assessment....
article 2007
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TNO Kwaliteit van Leven (author), van Hemmen, J.J. (author), Groenewold, M. (author), Tjoe Nij, E. (author), van de Sandt, H. (author)
In het programma Chemische en Biologische Gezondheidsrisico’s is in de periode 2003-2006 aan veel verschillende projecten gewerkt. Die hadden tot doel om het kennisniveau van TNO up-to-date te houden en op speerpunten te versterken. De projecten draaiden vooral om het ontwikkelen van instrumenten voor de implementatie van de wet- en regelgeving...
report 2007
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Marquart, H. (author), Warren, N.D. (author), Laitinen, J. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
Dermal exposure needs to be addressed in regulatory risk assessment of chemicals. The models used so far are based on very limited data. The EU project RISKOFDERM has gathered a large number of new measurements on dermal exposure to industrial chemicals in various work situations, together with information on possible determinants of exposure....
article 2006
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van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
article 2006
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Warren, N.D. (author), Marquart, H. (author), Christopher, Y. (author), Laitinen, J. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
The regulatory risk assessment of chemicals requires the estimation of occupational dermal exposure. Until recently, the models used were either based on limited data or were specific to a particular class of chemical or application. The EU project RISKOFDERM has gathered a considerable number of new measurements of dermal exposure together with...
article 2006
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Meuling, W.J. (author), Ravensberg, L.C. (author), Roza, L. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
Objective: The methods and results are described of a study on the dermal absorption of chlorpyrifos (CPF) in humans established via urinary excretion of the metabolite 3,5,6-trichloro-2-pyridinol (TCP). Methods: Two dermal, single, doses of CPF were applied in two study groups (A and B) each comprising three apparently healthy male volunteers...
article 2005
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van Wendel de Joode, B. (author), van Hemmen, J.J. (author), Meijster, T. (author), Major, V. (author), London, L. (author), Kromhout, H. (author), TNO Kwaliteit van Leven (author)
Valid and reliable semi-quantitative dermal exposure assessment methods for epidemiological research and for occupational hygiene practice, applicable for different chemical agents, are practically nonexistent. The aim of this study was to assess the reliability of a recently developed semi-quantitative dermal exposure assessment method (DREAM)...
article 2005
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van Wendel de Joode, B. (author), Vermeulen, R. (author), van Hemmen, J.J. (author), Fransman, W. (author), Kromhout, H. (author), TNO Kwaliteit van Leven (author)
Background: The authors recently developed a Dermal Exposure Assessment Method (DREAM), an observational semiquantitative method to assess dermal exposures by systematically evaluating exposure determinants using pre-assigned default values. Aim: To explore the accuracy of the DREAM method by comparing its estimates with quantitative dermal...
article 2005
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Brouwer, D.H. (author), de Pater, N.A.J. (author), Zomer, C. (author), Lurvink, M.W.M. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven TNO Defensie en Veiligheid (author)
The concept of occupational air requirement (OAR), representing the quantity of air required to dilute the vapor concentration in the work environment resulting from 11 product to a concentration below the occupational exposure limit (OEL), was considered to have potential to discriminate between paints that can and cannot be used safely. The...
article 2005
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van Hemmen, J.J. (author)
Dermal exposure to industrial chemicals during work is of major concern in the risk assessment of chemicals. Current approaches in procedures for European legislation are not based on experimental data of dermal exposure in the workplace because they are lacking. A project was funded to overcome this problem. In this paper an overview is given...
article 2005
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van Hemmen, J.J. (author), TNO Voeding (author)
Chemicals / CAS: 4,4' methylenedianiline, 101-77-9; Hazardous Substances.
article 2004
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Rajan-Sithamparanadarajah, R. (author), Roff, M. (author), Delgado, P. (author), Eriksson, K. (author), Fransman, W. (author), Gijsbers, J.H.J. (author), Hughson, G. (author), Mäkinen, M. (author), van Hemmen, J.J. (author), TNO Voeding (author)
Workplace dermal exposure assessment is a complex task that aims to understand the dynamic interaction between the skin and the hazardous substances present in the surrounding environment. A European project known as RISKOFDERM gathered dermal exposure data in 85 workplaces (industrial and other types) in five countries in Europe. In order to...
article 2004
Searched for: author:"van Hemmen, J.J."
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