A short story about the life of Curt Brunnée

Multivariate relations between data sets: Canonical correlation of mass spectral and chromatographic results

Performance of a moving belt liquid chromatography-mass spectrometry interface

Determination of progesterone by liquid chromatography - mass spectrometry using a moving-belt interface and isotope dilution

Progesterone can be determined rapidly and accurately with the method presented, using isotope dilution LC-MS with a moving-belt interface. Deactivation is very useful in that it minimizes belt memory effects and optimizes belt desorption characteristics. Since the moving-belt properties were found to change during time with respect to the...

The applicability of field desorption mass spectrometry and liquid chromatography/mass spectrometry for the analysis of the pungent principles of capsicum and black pepper

Derivatization and mass spectrometric behaviour of catecholamines and their 3-O-methylated metabolites

A method has been developed for the derivatization of both catecholamines (dopamine, noradrenaline and adrenaline) and their 3-O-methylated metabolites (3-methoxytyramine, normetanephrine and metanephrine) in a single run. The compounds were first incubated with methanolic hydrochloric acid to methylate those compounds that contain a benzylic...

Analysis of pepper and capsicum oleoresins by high-performance liquid chromatography-mass spectrometry and field desorption mass spectrometry

Using a combination of high-performance liquid chromatography-mass spectrometry with a moving-belt interface, field desorption mass spectrometry and high-resolution accurate mass electron impact mass spectrometry, the major components of the oleoresins of black pepper and capsicum have been identified. Nordihydro-, dihyro- and homo-capsaicin...

Biomimetic synthesis of neodihydrothebaine and bractazonine from thebaine

Photochemical irradiation of the morphinan alkaloid thebaine 1 followed by reduction, affords the dibenz[d,f]azonine alkaloids neodihydrothebaine 2 and bractazonine 3, in a sequence paralleling the proposed biosynthesis of these alkaloids in Papaver bracteatum. ?? 1984.

Comparison of field desorption and Fast Atom Bombardment mass spectrometry

Investigations carried out to compare fast atom bombardment in positive and negative ion mode - combined with low or high resolution - with field desorption snowed that the former technique is more easily feasible. It proouces more fragment ions as compared with field desorption, which is a favourable aspect as regards structure elucidation, but...

Evaluation of field-desorption and fast atom-bombardment mass spectrometric profiles by pattern recognition techniques

Field-desorption and fast atom-bombardment mass spectrometry are promising techniques for generating profiles of complex mixture of non-volatile compounds. This was concluded from results obtained with urine and wine samples. Pattern recognition techniques, such as non-linear mapping, K-nearest neighbours and principal component analysis, in...

A fast atom bombardment study of methionine in combination with deuterium labelling

The mechanism of ion formation from methiomine under fast atom bombardment conditions shows similarities with those reported in secondary ion, laser desorption and field desorption mass spectrometry. Deuterium labelling has indicated that the mode of fragmentation of this compound upon fast atom bombardment closely resembles that observed under...

Survey of the contamination of Dutch coastal water by chlorinated hydrocarbons, including the occurrence of methylthio-pentachlorobenzene and di-(methylthio)tetrachlorobenzene

In 1976 contamination of Dutch coastal waters by organochlorine compounds was assessed by analysing mussels, Mytilus edulis, as an indicator-organism. HCB, dieldrin, endrin, p,p'-DDT, p,p'-TDE and PCB's were detected, and also two new compounds previously unknown in the aquatic fauna. Using gas-liquid chromatography, mass spectrometry and 13C...

Combined gas chromatography-mass spectrometry: A powerful tool in analytical chemistry

A brief historical survey is given, together with a review of the main requirements for obtaining an optimal GC-MS system. Special attention is paid to the many different coupling techniques that have been developed during the last 15 years. The necessity for computerization and the various operational techniques applied in GC-MS are discussed...

Residues of pentachloronitrobenzene and related compounds in greenhouse soils

Pentachloronitrobenzene (PCNB, also known as Quintozene, Terraclor) is used as a soil fungicide in greenhouses, mainly for the control of Rhizoctonia and Botrytis in lettuce. During an examination (by gas liquid chromatography) of a number of soil samples from greenhouses, not only a PCNB peak was found in the chromatograms, but also several...

The odour of white bread II. Identification of components in pentane-ether extracts

Volatile constituents of white bread, isolated by pentane-ether extraction, were fractionated on a packed column, and identified by combined gas chromatography-mass spectrometry. 52 components were identified, of which 42 had not been reported previously to occur in the aroma of white bread. Several of these belong to pyrazines, lactones, and...

Identification and toxicological evaluation of chlorinated dibenzofuran and chlorinated naphthalene in two commercial polychlorinated biphenyls

In a previous study (Vos & Koeman, Toxic. appl. Pharmac. 1970. In press) a significant difference in toxicity was found between three commercial polychlorinated biphenyl (PCB) preparations, high mortality, liver necrosis and chick oedema-like lesions being associated with only two of the compounds tested. In the present study, column and gas...

Chlorinated biphenyls in fish, mussels and birds from the river rhine and the netherlands coastal area

Polychlorinated biphenyls are widely used in industry, and they are now making an appearance in the world's wildlife. Besides being a hazard in their own right, they interfere with the detection of organochlorine insecticides such as DDT. © 1969 Nature Publishing Group. Chemicals/CAS: liver extract, 72980-85-9; tissue extract, 1390-94-9, 8001-49...

Ergebnisse mit einer optimierten Kopplung von Gas-Chromatograph und Massenspektrometer

If a gas-chromatograph is connected to a mass spectrometer, both the usable separating power of the column and the detection power of the mass spectrometric analysis depends, to a considerable extent, on the design of the link between the two instruments. Results of gas flow experiments performed with different links are given. These experiments...