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Smits, M. (author), Verhoeckx, K. (author), Knulst, A. (author), Welsing, P. (author), de Jong, A. (author), Houben, G.F. (author), Le, T.M. (author)Predicting the allergenicity of novel proteins is challenging due to the absence of validated predictive methods and a well-defined reference set of proteins. The prevalence of sensitization could be a parameter to select reference proteins to characterize allergenic proteins. This study investigated whether the prevalence of sensitization of...article 2021
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Smits, M. (author), Nooijen, I. (author), Redegeld, F. (author), de Jong, A. (author), Le, T.M. (author), Knulst, A. (author), Houben, G.F. (author), Verhoeckc, K.C.M. (author)Scope: No accepted and validated methods are currently available which can accurately predict protein allergenicity. In this study, the role of digestion and transport on protein allergenicity is investigated. Methods and results: Peanut allergens (Ara h 1, 2, 3, and 6) and a milk allergen (β-lactoglobulin) are transported across pig intestinal...article 2021
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Smits, M. (author), Meijerink, M. (author), Le, T.M. (author), Knulst, A. (author), de Jong, A. (author), Caspers, M.P.M. (author), Lima, E.S. (author), Babe, L. (author), Ladics, G. (author), McClain, S. (author), Houben, G.F. (author), Verhoeckx, K. (author)Background: Food proteins differ in their allergenic potential. Currently, there is no predictive and validated bio-assay to evaluate the allergenicity of novel food proteins. The objective of this study was to investigate the potential of a human peripheral blood mononuclear cell (PBMC) gene expression assay to identify biomarkers to predict...article 2021
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Calvert, S.C. (author), Rypkema, J. (author), Holleman, B. (author), Azulay, D. (author), de Jong, A. (author)This study investigates different methods to visualise uncertainty in static representations of probabilistic traffic models predictions on road-networks. Although various graphical cues may be used to represent uncertainty it is not a priori clear which of them are most suited for this purpose, since their legibility, intelligibility and the...article 2017
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van der Walle, P. (author), Kramer, E. (author), van der Donck, J.C.J. (author), Mulckhuyse, W.F.W. (author), Nijsten, L. (author), Bernal Arango, F.A. (author), de Jong, A. (author), van Zeijl, E. (author), Spruit, W.E.T. (author), van den Berg, J.H. (author), Nanda, G. (author), van Langen-Suurling, A.K. (author), Alkemade, P.F.A. (author), Pereira, S.F. (author), Maas, D.J. (author)Particle defects are important contributors to yield loss in semi-conductor manufacturing. Particles need to be detected and characterized in order to determine and eliminate their root cause. We have conceived a process flow for advanced defect classification (ADC) that distinguishes three consecutive steps; detection, review and classification...conference paper 2017
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Prodan, A. (author), Brand, H. (author), Imangaliyev, S. (author), Tsivtsivadze, E. (author), van der Weijden, F. (author), de Jong, A. (author), Paauw, A. (author), Crielaard, W. (author), Keijser, B. (author), Veerman, E. (author)A cross-sectional observational study was conducted to evaluate the inter-individual variation in the MALDI-TOF MS peptide profiles of unstimulated whole saliva in a population of 268 systemically healthy adults aged 18-30 yr (150 males and 118 females) with no apparent caries lesions or periodontal disease. Using Spectral Clustering, four...article 2016
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Lupek, T. (author), Mischo, H. (author), Benndorf, J. (author), Buxton, M. (author), Nienhaus, K. (author), Rattmann, L. (author), Korre, A. (author), Soares, A. (author), De Jong, A. (author), Jeannee, N. (author), Graham, P. (author), Buttgereit, D. (author), Gehlen, C. (author), Eijkelkamp, F. (author), Sandtke, M. (author), Wilsnack, T. (author)With regard to the EU funded project 'Real-Time Mining' a sensorbased acquisition, collection and transmission of data for the resource extraction process will be developed. The key concept promotes the change in paradigm from a discontinuous to a continuous process monitoring. Especially concerning material characterization, machine performance...conference paper 2016
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Jayasena, S. (author), Smits, M. (author), Fiechter, D. (author), de Jong, A. (author), Nordlee, J. (author), Baumert, J. (author), Taylor, S.L. (author), Pieters, R.H. (author), Koppelman, S.J. (author)Six commercial peanut enzyme-linked immunosorbent assay kits were assessed for their ability to recover peanut from the standard reference material 2387 peanut butter and also for their specificity in detecting four major peanut allergens, Ara h 1, Ara h 2, Ara h 3, and Ara h 6. The percentage recovery of peanut from peanut butter differed...article 2015
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van Erp, J.B. (author), Toet, A. (author), Meijer, K. (author), Janssen, J. (author), de Jong, A. (author)We developed active tangibles (Sensators) that can be used in combination with multitouch tabletops and that can provide multisensory (visual, auditory, and vibrotactile) feedback. For spatial alignment and rotation tasks we measured subjective user experience and objective performance with these Sensators. We found that active feedback...conference paper 2015
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Havenaar, R. (author), de Jong, A. (author), Koenen, M.E. (author), van Bilsen, J. (author), Janssen, A.M. (author), Labij, E. (author), Westerbeek, H.J.M. (author)Aim of this study was to investigate the digestion of transglutaminase cross-linked caseinate (XLC) versus native caseinate (NC) in solution and in cheese spread under digestive conditions for adults and children mimicked in a gastrointestinal model. Samples were collected for gel electrophoresis and nitrogen analysis. The results showed no...article 2013
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de Jong, A. (author), Spruijt, M. (author)In the current work evaluation of CO2 release velocity profiles is determined using Particle Image Velocimetry (PIV). The formation of solid CO2 particles using the rapid expansion of nozzle flow is used as a seeder particle, making the method truly nonintrusive and negates the use of special seeder equipment. Preliminary tests have been...article 2013
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Hulsbosch-Dam, C. (author), de Jong, A. (author), Zevenbergen, J. (author), Peeters, R. (author), Spruijt, M. (author)High-speed CO2 release experiments from a pressurized vessel have been conducted for a range of storage pressures nozzle diameters. The experiments are conducted to validate and develop models for accidental releases of CO2 during transport. In cooperation with DNV-KEMA lab (Groningen, The Netherlands), medium scale experiments with a 500 liter...article 2013
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Bazley, C.M. (author), de Jong, A. (author), Vink, P. (author)A human factors specialist researched the expectations of a culturally and professionally diverse team throughout a year long participatory design process of a large processing facility. For a deeper understanding of high-level team expectations and characteristics, the specialist collected data and information through in-situ ethnography and...article 2012
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Bronkhorst, A.J. (author), van Bentum, C.A. (author), Geurts, C.P.W. (author), de Jong, A. (author)Particle Image Velocimetry (PIV) and pressure measurements were performed on a highrise model with a height (H) of 0.48 m and a width (B) of 0.12 m in a turbulent atmospheric boundary layer. Experiments were carried out for an isolated model and four tandem configurations with varying separation distance (S) between the models. Mean and standard...conference paper 2012
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van der Kleij, R. (author), de Jong, A. (author), te Brake, G.M. (author), Greefe, T.E. (author), TNO Defensie en Veiligheid (author)An experiment evaluated network-aware support to increase understanding of the factors that are important for successful teamwork in mobile geographically dispersed teams of first responders. Participants performed a simulated search and rescue team task and were equipped with a digitized map and realtime situation updates on the location of...article 2009
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Plat, J. (author), de Jong, A. (author), Volger, O.L. (author), Princen, H.M.G. (author), Mensink, R.P. (author), TNO Kwaliteit van Leven (author)Intestinal absorption of plant sterols and stanols is much lower as compared with that of cholesterol; and therefore, serum concentrations are low. Circulating plant sterols and stanols are incorporated into tissues. However, hardly any data are available about tissue distributions of individual plant sterols and stanols, particularly in...article 2008
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- de Jong, A. (author), van Veen, S. (author), TNO Kwaliteit van Leven (author) article 2005
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- de Jong, A. (author), TNO Kwaliteit van Leven (author) article 2005
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de Visser, P.C. (author), van Hooft, P.A.V. (author), de Vries, A.-M. (author), de Jong, A. (author), van der Marel, G.A. (author), Overkleeft, H.S. (author), Noort, D. (author), TNO Defensie en Veiligheid (author)An array of analogues of the cationic antimicrobial peptide drosocin was synthesized containing substitutions of Tyr6 and Ser7 in order to increase the proteolytic stability. Stabilizing the N-terminus with unnatural amino acids increased the serum stability of analogues by almost a factor 30 over an 8 h period. © 2005 Elsevier Ltd. All rights...article 2005
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- Jongbloed, H. (author), de Jong, A. (author), TNO Voeding (author) article 2004
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