Sensitivity of fetal RHD screening for safe guidance of targeted anti-D immunoglobulin prophylaxis: Prospective cohort study of a nationwide programme in the Netherlands

Objective To determine the accuracy of non-invasive fetal testing for the RHD gene in week 27 of pregnancy as part of an antenatal screening programme to restrict anti-D immunoglobulin use to women carrying a child positive for RHD. Design Prospectively monitoring of fetal RHD testing accuracy compared with serological cord blood typing on...

Foetale resus-D-typering toegevoegd aan prenatale screening op infectieziekten en erytrocytenimmunisatie[Foetal Rhesus-D typing added to antenatal screening for infectious diseases and erythrocyte immunisation]

Objective In the Netherlands, postnatal anti-Rhesus(D)-prophylaxis (anti-D) for RhD-negative pregnant women was introduced in 1969, followed by the introduction of antenatal anti-D administration in 1998. Screening for RhD and administration of anti-D has led to a reduction of the incidence of RhD alloimmunisation from 3.5% in 1969 to 0.29% in...

Prenatal Fetal DNA Testing for Predicting HDFN, FNAIT, and RhIG Candidacy

Landelijke evaluatie van de wijzigingen in het bevolkingsonderzoek PSIE per 1 juli 2011 Deelrapport 2: Procesevaluatie

Fetal RHD typing can be safely used to target both antenatal and postnatal anti-D prophylaxis

A nation-wide fetal RHD screening programme for targeted antenatal and postnatal anti-D

In the Netherlands, since 1 July 2011, both antenatal anti-D immunoprophylaxis (1000 IU in the 30th week of gestation) and postnatal prophylaxis (1000 IU) is administered to only those women for whom a fetal RHD typing, performed in week 27 of pregnancy, predicts the presence of a D-positive child. The fetal RHD screening is part of the...

Landelijke evaluatie van de wijzigingen in het bevolkingsonderzoek PSIE per 1 juli 2011 Deelrapport 1: Accuratesse van de foetale Rhesus(D)-typering.

Reduced topoisomerase II activity in multidrug resistant human non-small cell lung cancer cell lines