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Hoiseth, K.V. (author), Kaptijn, N. (author), de Boer, A. (author), Rots, J.G. (author)In connection with renovation of a skew plate fly-over in concrete, nonlinear analyses have been performed, to assess the load carrying capacity before and after strengthening. The FEM-model was justified by linear analyses, where the influence of spatial resolution, shear and longitudinal curvature was studied. The tensile properties of...conference paper 1996
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van den Bogaart, F.L.M. (author), de Hek, A.P. (author), de Boer, A. (author), TNO Fysisch en Elektronisch Laboratorium (author)A 3-Watt and a 5-Watt high-efficiency high-power amplifier are presented. The amplifiers are manufactured in a GaAs MESFET process. The 3-watt amplifier exhibits 4 Watt output power at 10.6 GHz with an associated PAE of 43% and more than 3 Watt output power with more than 30% PAE from 8 GHz to 11.3 GHz. The 5-Watt amplifier exhibits 7W output...conference paper 1996
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Kuilboer, C.P.M. (author), Kaptijn, N. (author), de Boer, A. (author), Hordijk, D.A. (author), Naaktgeboren, N.M. (author)De introductie van de nieuwe generatie voorschriften maakt het mogelijk om het ontwerp van bijvoorbeeld betonnen kokerliggers ten opzichte van de huidige praktijk op een aantal punten te wijzigen. Vooral hetfeit dat kokerliggers niet meer behoeven te worden ontwor pen in volledig voorgespannen beton, roept vragen op. Het kan betekenen dat de con...article 1995
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Ganesh, S. (author), Sier, C.F.M. (author), Griffioen, G. (author), Vloedgraven, H.J.M. (author), de Boer, A. (author), Welvaart, K. (author), van de Velde, C.J.H. (author), van Krieken, J.H.J.M. (author), Verheijen, J.H. (author), Lamers, C.B.H.W. (author), Verspaget, H.W. (author), Instituut voor Verouderings- en Vaatziekten Onderzoek TNO (author)Human colorectal carcinogenesis has been shown previously to be associated with impressive changes in the tissue levels of plasminogen activators and their inhibitors, exemplified by an increase in the urokinase-type plasminogen activator (u-PA) and the inhibitors PAI-1 and PAI-2, and a decrease in tissue-type plasminogen activator (t-PA). In...article 1994
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de Boer, A. (author), Kluft, C. (author), Dooijewaard, G. (author), Kasper, F.J. (author), Kroon, J.M. (author), Breimer, D.D. (author), Stiekema, J.C. (author), Cohen, A.F. (author)The effects of heparin (5,000 IU i.v.) and the low molecular weight heparinoid Org 10172 (Orgaran) (3,250 anti-Xa units i.v.) on components of the fibrinolytic system were studied in two double-blind, randomised, placebo-controlled, cross-over trials using healthy subjects. In study A (n = 6) the effects were studied during rest and standardized...article 1992
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de Boer, A. (author), Kluft, C. (author), Kroon, J.M. (author)The influence of changes in liver blood flow on the clearance of rt-PA was studied both in healthy subjects and in a perfused rat liver model. Liver blood flow in healthy subjects was documented indirectly by the clearance of indocyanine green (ICG). Exercise reduced liver blood flow on average by 57% with a 95% confidence interval (95% CI)...article 1992
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Dooijewaard, G. (author), de Boer, A. (author), Turion, P.N.C. (author), Cohen, A.F. (author), Breimer, D.D. (author), Kluft, C. (author), Gaubius Instituut TNO (author)The enhancement of the blood fibrinolytic potential by physical exercise is generally attributed to the release of tissue-type plasminogen activator (t-PA) from the vessel wall. In this study we have investigated the possible contribution of urokinase-type plasminogen activator (u-PA). Six healthy male volunteers (age 21-25 years) were screened...article 1991