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Steens, J.A. (author), Zhu, Y. (author), Taylor, D.W. (author), Bravo, J.P.K. (author), Prinsen, S.H.P. (author), Schoen, C.D. (author), Keijser, B.J.F. (author), Ossendrijver, M. (author), Hofstra, L.M. (author), Brouns, S.J.J. (author), Shinkai, A. (author), van der Oost, J. (author), Staals, R.H.J. (author)Characteristic properties of type III CRISPR-Cas systems include recognition of target RNA and the subsequent induction of a multifaceted immune response. This involves sequence-specific cleavage of the target RNA and production of cyclic oligoadenylate (cOA) molecules. Here we report that an exposed seed region at the 3′ end of the crRNA is...article 2021
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Schweiker, M. (author), Andréu, M. (author), Al-Atrash, F. (author), Al-Khatri, H. (author), Alprianti, R.R. (author), Alsaad, H. (author), Amin, R. (author), Ampatzi, E. (author), Arsano, A.Y. (author), Azar, E. (author), Bannazadeh, B. (author), Batagarawa, A. (author), Becker, S. (author), Buonocore, C. (author), Cao, B. (author), Choi, J.H. (author), Chun, C. (author), Daanen, H.A.M. (author), Damiati, S.A. (author), Daniel, L. (author), de Vecchi, R. (author), Dhaka, S. (author), Domínguez-Amarillo, S. (author), Dudkiewicz, E. (author), Edappilly, L.P. (author), Fernández-Agüera, J. (author), Folkerts, M. (author), Frijns, A. (author), Gaona, G. (author), Garg, V. (author), Gauthier, S. (author), Ghaffari Jabbari, S. (author), Harimi, D. (author), Hellwig, R.T. (author), Huebner, G.M. (author), Jin, Q. (author), Jowkar, M. (author), Kim, K. (author), King, N. (author), Kingma, B.R.M. (author), Koerniawan, M.D. (author), Kolarik, J. (author), Kumar, S. (author), Kwok, A. (author), Lamberts, R. (author), Laska, M. (author), Lee, M.C.J. (author), Lee, Y. (author), Lindermayr, V. (author), Mahaki, M. (author), Marcel-Okafor, U. (author), Marín-Restrepo, L. (author), Marquardsen, A. (author), Martellotta, F. (author), Mathur, J. (author), Mino-Rodriguez, I. (author), Montazami, A. (author), Mou, D. (author), Moujalled, B. (author), Nakajima, M. (author), Ng, E. (author), Okafor, M. (author), Olweny, M. (author), Ouyang, W. (author), Lígia Papst de Abreu, A. (author), Pérez-Fargallo, A. (author), Rajapaksha, I. (author), Ramos, G. (author), Rashid, S. (author), Reinhart, C.F. (author), Rivera, I.M. (author), Salmanzadeh, M. (author), Schakib-Ekbatan, K. (author), Schiavon, S. (author), Shooshtarian, S. (author), Shukuya, M. (author), Soebarto, V. (author), Suhendri, S. (author), Tahsildoost, M. (author), Tartarini, F. (author), Teli, D. (author), Tewari, P. (author), Thapa, S. (author), Trebilcock, M. (author), Trojan, J. (author), Tukur, R.B. (author), Voelker, C. (author), Yam, Y. (author), Yang, L. (author), Zapata-Lancaster, G. (author), Zhai, Y. (author), Zhu, Y. (author), Zomorodian, Z. (author)People's subjective response to any thermal environment is commonly investigated by using rating scales describing the degree of thermal sensation, comfort, and acceptability. Subsequent analyses of results collected in this way rely on the assumption that specific distances between verbal anchors placed on the scale exist and that relationships...article 2020
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Zhu, Y. (author), Rougieux, F. (author), Grant, N.E. (author), Du Guzman, J.A.T. (author), Murphy, J.D. (author), Markevich, V.P. (author), Coletti, G. (author), Peaker, A.R. (author), Hameiri, Z. (author)—Float-zone (FZ) silicon is usually assumed to be bulk defect-lean and stable. However, recent studies have revealed that detrimental defects can be thermally activated in FZ silicon wafers and lead to a reduction of carrier lifetime by up to two orders of magnitude. A robust methodology which combines different characterization techniques and...article 2020
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Zhu, Y. (author), Juhl, M.K. (author), Coletti, G. (author), Hameiri, Z. (author)In photoconductance (PC) based carrier lifetime measurement, artificially high values at low-to-medium injection levels are often observed because of the presence of minority carrier traps in the sample. In this paper, we demonstrate that the traps in n-type Czochralski silicon are in a transient regime under the typical quasi-steady-state...article 2019
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Schweiker, M. (author), Adul-Zahra, A. (author), André, M. (author), Al-Atrash, F. (author), Al-Khatri, H. (author), Risky Alprianti, R. (author), Alsaad, H. (author), Amin, R. (author), Ampatzi, E. (author), Arsano, A.Y. (author), Azadeh, M. (author), Azar, E. (author), Bahareh, B. (author), Batagarawa, A. (author), Becker, S. (author), Buonocore, C. (author), Cao, B. (author), Choi, J.H. (author), Chun, C. (author), Daanen, H. (author), Damiati, S.A. (author), Daniel, L. (author), De Vecchi, R. (author), Dhaka, S. (author), Domínguez-Amarillo, S. (author), Dudkiewicz, E. (author), Edappilly, L.P. (author), Fernández-Agüera, J. (author), Folkerts, M. (author), Frijns, A. (author), Gaona, G. (author), Garg, V. (author), Gauthier, S. (author), Jabbari, S.G. (author), Harimi, D. (author), Hellwig, R.T. (author), Huebner, G.M. (author), Jin, Q (author), Jowkar, M. (author), Kania, R. (author), Kim, J. (author), King, N. (author), Kingma, B.R.M. (author), Koerniawan, D. (author), Jakub Kolarik, (author), Shailendra Kumar, (author), Alison Kwok, (author), Roberto Lamberts, (author), Marta Laska, (author), M. C. Jeffrey Lee, (author), Lee, Y. (author), Lindermayr, V. (author), Mahaki, M. (author), Marcel-Okafor, U. (author), Marín-Restrepo, L. (author), Marquardsen, A. (author), Martellotta, F. (author), Mathur, J. (author), McGill, G. (author), Mino-Rodriguez, I. (author), Mou, D. (author), Moujalled, B. (author), Nakajima, M. (author), Ng, E. (author), Okafor, M. (author), Olweny, M. (author), Ouyang, W. (author), Ligia Papst de Abreu, A. (author), Alexis Pérez-Fargallo, A. (author), Indrika Rajapaksha, I. (author), Greici Ramos, G. (author), Saif Rashid, S. (author), Christoph F. Reinhart, C.F. (author), Rivera, M.I. (author), Salmanzadeh, M. (author), Schakib-Ekbatan, K. (author), Schiavon, S. (author), Shooshtarian, S. (author), Shukuya, M. (author), Soebarto, V. (author), Suhendri, S. (author), Tahsildoost, M. (author), Tartarini, F. (author), Teli, D. (author), Tewari, P. (author), Thapa, S. (author), Trebilcock, M. (author), Trojan, J. (author), Tukur, R.B. (author), Voelker, C. (author), Yam, Y. (author), Liu Yang, L. (author), Zapata-Lancaster, G. (author), Zhai, (author), Zhu, Y. (author), Zomorodian, Z.S. (author)Thermal discomfort is one of the main triggers for occupants’ interactions with components of the built environment such as adjustments of thermostats and/or opening windows and strongly related to the energy use in buildings. Understanding causes for thermal (dis-)comfort is crucial for design and operation of any type of building. The...article 2019
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Zhu, Y. (author), Rougieux, F. (author), Grant, N. (author), Mullins, J. (author), de Guzman, J.A. (author), Murphy, J.D. (author), Markevich, V.P. (author), Coletti, G. (author), Peaker, A.R. (author), Hameiri, Z. (author)Float-zone silicon has been long assumed to be bulk defect free and stable. Nevertheless, recently it was found that upon annealing between 450 °C to 700 °C detrimental defects can be activated in this material. Previous studies via deep level transient spectroscopy have identified several defect levels. However, it is still not clear which of...conference paper 2019
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Lee Chin, R. (author), Zhu, Y. (author), Coletti, G. (author), Binetti, S. (author), Pollard, M. (author), Hameiri, Z. (author)In this study, we use temperature-dependent microphotoluminescence spectroscopy to investigate non-uniform bulk defects in n-type Czochralski and float-zone silicon wafers. For both wafer types, we observe defect photoluminescence (PL) with peak energy between 0.78 eV and 0.85 eV emerge as the temperature is decreased from 300 K to 80 K, along...conference paper 2018
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Coletti, G. (author), Jensen, M.A. (author), Vargas, C. (author), Zhu, Y. (author), Chan, C. (author), Payne, D. (author), Hameiri, Z. (author)In p-type multicrystalline silicon solar cells, carrier-induced degradation (CID) can cause up to 10% relative reduction in conversion efficiency. Although, a great concern has been drawn on this degradation in the photovoltaic community, the nature of this degradation is still yet unknown. In this contribution, the recombination parameters of...article 2017
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Coletti, G. (author), Zhu, Y. (author), Hameiri, Z. (author), Thong Le Gia, Quoc (author), Juhl, M.K. (author)Defect parameter solution surface is a widely accepted method to determine the values of the energy level and the carrier capture cross sections of a defect from injection-dependent lifetime measurements. Results of the defect parameter solution surface come from the recognition of intersection points, which can be difficult when the doping or...article 2017
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Kaptein, R. (author), Zhu, Y. (author), Koot, G. (author), Redi, J. (author), Niamut, O. (author)The use of social TV applications to enhance the experience of live event broadcasts has become an increasingly common practice. An event profile, defined as a set of keywords relevant to an event, can help to track messages related to these events on social networks. We propose an event profiler that retrieves relevant and interesting tweets in...conference paper 2015
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- Zhu, Y. (author), Havenaar, R. (author), Venema, K. (author) article 2011
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- Zhu, Y. (author) article 2011
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Erisman, J.W. (author), Cellier, P. (author), de Vries, W. (author), Sutton, M.A. (author), Manning, W.J. (author), Jones, K.C. (author), Nowack, B. (author), Wiegand, C. (author), Zhu, Y.-G. (author), d. Vries, W. (author)-article 2011
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Jovetic, S. (author), Zhu, Y. (author), Marcone, G.L. (author), Marinelli, F. (author), Tramper, J. (author), TNO Kwaliteit van Leven (author)Most infections are caused by bacteria, many of which are ever-evolving and resistant to nearly all available antibiotics. β-Lactams and glycopeptides are used to combat these infections by inhibiting bacterial cell-wall synthesis. This mechanism remains an interesting target in the search for new antibiotics in light of failed genomic...article 2010
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Chen, H. (author), Xu, X. (author), Zhu, Y. (author), TNO Kwaliteit van Leven (author)The objectives of this study were to investigate the effect of fermentation medium on the hydroxyl radical scavenging activity of exopolysaccharides from Inonotus obliquus by response surface methodology (RSM). A two-level fractional factorial design was used to evaluate the effect of different components of the medium. Corn flour, peptone, and...article 2010
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Zhang, Y. (author), Zhu, Y. (author), Zhu, Y. (author), Li, Y. (author), TNO Kwaliteit van Leven (author)Good physiological performance of industrial microbes is crucial for successful bioprocesses. Conventional metabolism-oriented engineering strategies often fail to obtain expected phenotypes owing to focusing narrowly on targeted metabolic capabilities while neglecting microbial physiological responses to environmental stresses. To meet the new...article 2009
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Shi, Y. (author), Xu, X. (author), Zhu, Y. (author), TNO Kwaliteit van Leven (author)Verticillium lecanii is an entomopathogen with high potential in biological control of pests. We developed a solid-state fermentation with sugarcane bagasse as carrier absorbing liquid medium to propagate V. lecanii spores. Using statistical experimental design, we optimized the medium composition for spore production. We first used one-factor...article 2009
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te Biesebeke, R. (author), Ruijter, G. (author), Rahardjo, Y.S.P. (author), Hoogschagen, M.J. (author), Heerikhuisen, M. (author), Levin, A. (author), van Driel, K.G.A. (author), Schutyser, M.A.I. (author), Dijksterhuis, J. (author), Zhu, Y. (author), Weber, F.J. (author), de Vos, W.M. (author), van den Hondel, K.A.M.J.J. (author), Rinzema, A. (author), Punt, P.J. (author)We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus in submerged fermentation (SmF) and SSF are compared and we observe a number of differences correlated with the different growth conditions. First,...article 2002
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Sreeramulu, G. (author), Zhu, Y. (author), Knol, W. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Fermented tea drink, Kombucha, can inhibit the growth of Shigella sonnei, Escherichia coli, Salmonella enteritidis and Salmonella typhimurium. Several metabolites were analyzed every two days during a 14-day Kombucha fermentation. Levels of acetic acid and gluconic acid were found to increase with fermentation time. No lactic acid or ethanol was...article 2001
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Hoogschagen, M. (author), Zhu, Y. (author), van As, H. (author), Tramper, J. (author), Rinzema, A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The respiration kinetics of Aspergillus oryzae on different varieties of whole wheat kernels were studied. Six wheat varieties were pretreated in two different ways. Five of the six substrates fermented similarly and independently of the pretreatment method. However, pretreatment affected fermentation of one variety of soft wheat (Apollo). T21H...article 2001
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