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Willems, N.M.B.K. (author), Langenbach, G.E.J. (author), Stoop, R. (author), den Toonder, J.M.J. (author), Mulder, L. (author), Zentner, A. (author), Everts, V. (author)The role of mature collagen cross-links, pentosidine (Pen) cross-links in particular, in the micromechanical properties of cancellous bone is unknown. The aim of this study was to examine nonenzymatic glycation effects on tissue stiffness of demineralized and non-demineralized cancellous bone. A total of 60 bone samples were derived from...article 2014
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- Willems, N.M.B.K. (author), Langenbach, G.E.J. (author), Everts, V. (author), Mulder, L. (author), Grünheid, T. (author), Bank, R.A. (author), Zentner, A. (author), van Eijden, T.M.G.J. (author) article 2011
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Willems, N.M.B.K. (author), Mulder, L. (author), Bank, R.A. (author), Grünheid, T. (author), den Toonder, J.M.J. (author), Zentner, A. (author), Langenbach, G.E.J. (author)Although bone-tissue stiffness is closely related to the degree to which bone has been mineralized, other determinants are yet to be identified. We, therefore, examined the extent to which the mineralization degree, collagen, and its cross-links are related to bone-tissue stiffness. A total of 50 cancellous and cortical bone samples were derived...article 2011
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Willems, N.M.B.K. (author), Langenbach, G.E.J. (author), Everts, V. (author), Mulder, L. (author), Grünheid, T. (author), Bank, R.A. (author), Zentner, A. (author), van Eijden, T.M.G.J. (author), TNO Kwaliteit van Leven (author)Collagen is an important constituent of bone, and it has been suggested that changes in collagen and mineral properties of bone are interrelated during growth. The aim of this study was to quantify age-related changes in collagen properties and the degree of mineralization of bone (DMB). The DMB in cancellous and cortical bone samples from the...article 2010