Thermomechanical modelling of sandwich panels with connections in fire resistance tests

This paper presents two full-scale fire resistance tests of sandwich panels with connections, to verify one way coupled fire-structure simulations. The heat transfer simulations agree well with the tests, however, the structural response simulations show some differences compared to the start of the first test, which is a sandwich panel façade....

Insulation pyrolysis for sandwich panel fire-structure simulations

A sandwich panel, as a very important component in building façade systems, consists of two thin walled plates plus an insulation core. For this core, traditionally materials like mineral wool have been used. However, polymer composites are increasingly used instead, for among others their higher stiffness, and better resistance to wind and...

Implementation of a pyrolysis model in two-way coupled fire-structure simulations

A two-scale FE model to address connections in coupled fire-structure simulations

A two-scale finite element model is proposed to improve two-way coupled fire-structure simulations. The model consists of (i) a global-scale model, which accounts for the structure, and (ii) a small-scale model for each connection. Structural parts on the global scale are connected by spring elements, which stiffness properties are updated by...

Bolt connection model for multi-scale two-way coupled fire thermo-mechanical facade simulations

A multi-scale approach is proposed to simulate the fire resistance of panels used in façades of buildings: Using existing models, fire is modelled by CFD, its effects in the façade found via a thermodynamical model. Then a thermomechanical model predicts the mechanical behaviour, using linear elastic springs for the connections holding the...

Proteomic and meatbolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice

We have recently demonstrated that stem cell antigen 1-positive (Sca-1(+)) progenitors exist in the vascular adventitia of apolipoprotein E-deficient (apoE(-/-)) mice and contribute to smooth muscle cell (SMC) accumulation in vein graft atherosclerosis. Using a combined proteomic and metabolomic approach, we now characterize these local...

Accelerated atherosclerosis and calcification in vein grafts: A study in APOE*3 Leiden transgenic mice

Vein grafts fail due to development of intimal hyperplasia and accelerated atherosclerosis. Many murine genetic models in which genes are overexpressed, deleted, or mutated have been introduced recently. Therefore, mouse models are very well suited to dissect the relative contribution of different genes in the development of accelerated...