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Wiese, M. (author), Schuren, F.H.J. (author), Smits, W.K. (author), Kuijpers, E.J. (author), Ouwens, A. (author), Heerikhuisen, M. (author), Vigsnaes, L. (author), van den Broek, T.J. (author), de Boer, P. (author), Montijn, R.C. (author), Vossen, J.M.B.M. (author)
Background: Clostridioides difficile is a Gram-positive anaerobic bacterium that can produce the toxins TcdA and/or TcdB and is considered an opportunistic pathogen. C. difficile is mainly transmitted as endospores, which germinate to produce the pathogenic vegetative cells under suitable conditions in the gut. To efficiently screen novel...
article 2022