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- TNO Kwaliteit van Leven (author), Arentsen, D. (author), van Beek, P.C. (author), Gallis, H.R. (author), van der Vorm, J.K.J. (author), Voshol, P. (author) book 2010
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TNO Kwaliteit van Leven (author), Verschuren, L. (author), Kooistra, T. (author), Bernhagen, J. (author), Voshol, P. (author), Ouwens, D.M. (author), van Erk, M. (author), de Vries-van der Weij, J. (author), Leng, L. (author), van Bockel, J.H. (author), Willems van Dijkl, K. (author), Fingerle-Rowson, G. (author), Bucala, R. (author), Kleemann, R. (author)Chronic inflammation in white adipose tissue (WAT) is positively associated with obesity, insulin resistance (IR) and the development of type 2 diabetes. The proinflammatory cytokine MIF (macrophage migration inhibitory factor) is an essential, upstream component of the inflammatory cascade. This study examines whether MIF is required for the...article 2009
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van Ginneken, V. (author), Verhey, E. (author), Poelmann, R. (author), Ramakers, R. (author), van Dijk, K.W. (author), Ham, L. (author), Voshol, P. (author), Havekes, L. (author), van Eck, M. (author), van der Greef, J. (author), TNO Kwaliteit van Leven (author)A metabolomic approach was applied to a mouse model of starvation-induced hepatic steatosis. After 24 h of fasting it appears that starvation reduced the phospholipids (PL), free cholesterol (FC), and cholesterol esters (CE) content of low-density lipoproteins (LDL). In liver lipid profiles major changes were observed using different techniques....article 2007