Searched for: author%3A%22Vogels%2C+J.%22
(1 - 14 of 14)
document
Leeman, W.R. (author), Rouhani-Rankouhi, T. (author), Vogels, J. (author), Krul, L. (author)
Recently, the European Food Safety Authority (EFSA) stated that the Threshold of Toxicological Concern
article 2016
document
Scholtes-Timmerman, M. (author), Bijlsma, S. (author), Vogels, J. (author)
article 2016
document
Wijn, R. (author), Vogels, J. (author)
Dit artikel laat zien dat het combineren van observaties van afwijkend gedrag door meerdere toezichthouders leidt tot betere oordelen over mogelijke kwaadwillige intenties dan oordelen van individuele toezichthouders. In de hier beschreven studie bekeken ervaren toezichthouders CCTV-beelden van een winkelcentrum waarin zakkenrollers actief waren...
article 2015
document
Kemmerling, J. (author), Fehlert, E. (author), Kuper, C.F. (author), Rühl-Fehlert, C. (author), Stropp, G. (author), Vogels, J. (author), Krul, C. (author), Vohr, H.W. (author)
Exposure to chemicals may have an influence on the immune system. Often, this is an unwanted effect but in some pharmaceuticals, it is the intended mechanism of action. Immune function tests and in depth histopathological investigations of immune organs were integrated in rodent toxicity studies performed according to an extended OECD test...
article 2015
document
Kuper, C.F. (author), Vogels, J. (author), Kemmerling, J. (author), Fehlert, E. (author), Rühl‐Fehlert, C. (author), Vohr, H.W. (author), Krul, C. (author)
Data in a toxicity test are evaluated generally per parameter. Information on the response per animal in addition to per parameter can improve the evaluation of the results. The results from the six studies in rats, described in the paper by Kemmerling, J., Fehlert, E., Rühl-Fehlert, C., Kuper, C.F., Stropp, G., Vogels, J., Krul, C., Vohr, H.-W....
article 2015
document
Bouma, H. (author), Vogels, J. (author), Aarts, O.A.J. (author), Kruszynski, K.J. (author), Wijn, R. (author), Burghouts, G.J. (author)
Camera surveillance and recognition of deviant behavior is important for the prevention of criminal incidents. A single observation of subtle deviant behavior of an individual may sometimes be insufficient to merit a follow-up action. Therefore, we propose a method that can combine multiple weak observations to make a strong indication that an...
conference paper 2013
document
van Doorn, M. (author), Vogels, J. (author), Tas, A. (author), van Hoogdalem, E.J. (author), Burggraaf, J. (author), Cohen, A. (author), van der Greef, J. (author), TNO Kwaliteit van Leven (author)
Aims: To explore the usefulness of metabolomics as a method to obtain a broad array of biomarkers for the pharmacological effects of rosiglitazone (RSG) in plasma and urine samples from patients with type 2 diabetes mellitus (T2DM) and healthy volunteers (HVs). Additionally, we explored the differences in metabolite concentrations between T2DM...
article 2007
document
Orešič, M. (author), Clish, C.B. (author), Davidov, E.J. (author), Verheij, E. (author), Vogels, J. (author), Havekes, L.M. (author), Neumann, E. (author), Adourian, A. (author), Naylor, S. (author), van der Greef, J. (author), Plasterer, T. (author), TNO Preventie en Gezondheid (author)
Multifactorial diseases present a significant challenge for functional genomics. Owing to their multiple compartmental effects and complex biomolecular activities, such diseases cannot be adequately characterised by changes in single components, nor can pathophysiological changes be understood by observing gene transcripts alone. Instead, a...
article 2004
document
'T Hart, B.A. (author), Vogels, J. (author), Bauer, J. (author), Brok, H.P.M. (author), Blezer, E. (author), TNO Voeding (author)
Early recognition of whether a product has potential as a new therapy for treating multiple sclerosis (MS) relies upon the quality of the animal models used in the preclinical trials. The promising effects of new treatments in rodent models of experimental autoimmune encephalomyelitis (EAE) have rarely been reproduced in patients suffering from...
article 2004
document
van der Greef, J. (author), Davidov, E. (author), Verheij, E. (author), Vogels, J. (author), van der Heijden, R. (author), Adourian, A.S. (author), Oresic, M. (author), Marple, E.W. (author), Naylor, S. (author), TNO Voeding (author)
bookPart 2003
document
Stierum, R. (author), Gaspari, M. (author), Dommels, Y. (author), Ouatas, T. (author), Pluk, H. (author), Jespersen, S. (author), Vogels, J. (author), Verhoeckx, K. (author), Groten, J. (author), van Ommen, B. (author)
Here, we describe a proteomics approach to study protein expression changes in differentiating Caco-2 cells. Caco-2 is a colorectal carcinoma cell line, which upon differentiation loses its tumorigenic phenotype and displays characteristics of mature enterocytes, including brush borders with microvilli. Cells were grown in culture flasks and...
article 2003
document
Tas, A. (author), Venema, K. (author), Wülfert, F. (author), Vogels, J. (author), Nijssen, B. (author), TNO Voeding (author)
article 2002
document
Centraal Instituut voor Voedingsonderzoek TNO (author), Vogels, J. (author)
doctoral thesis 2002
document
Vogels, J. (author), Venekamp, J. (author), Tas, A. (author), TNO Voeding (author)
article 1996
Searched for: author%3A%22Vogels%2C+J.%22
(1 - 14 of 14)