Cost-effectiveness of newborn screening for cystic fibrosis determined with real-life data

BACKGROUND: Previous cost-effectiveness studies using data from the literature showed that newborn screening for cystic fibrosis (NBSCF) is a good economic option with positive health effects and longer survival. METHODS: We used primary data to compare cost-effectiveness of four screening strategies for NBSCF, i.e. immunoreactive trypsinogen...

Parental knowledge reduces long term anxiety induced by false-positive test results after newborn screening for cystic fibrosis

Background: False-positive screening results in newborn screening for cystic fibrosis may lead to parental stress, family relationship problems and a changed perception of the child's health. Aim of the study: To evaluate whether parental anxiety induced by a false positive screening result disappears after six months and to assess whether a...

To know or not to know, disclosure of a newborn carrier screening test result for cystic fibrosis

To know or not to know, disclosure of a newborn carrier screening test result for cystic fibrosis

Purpose: Most newborn screening (NBS) strategies for Cystic Fibrosis (CF) also identify carriers. However, it is unclear if parents want to be informed about their child's carrier status or not. Methods: Focus group discussions with pregnant couples to explore their opinions about disclosure of a carrier result for CF of their newborn. Results:...

Novel strategies in newborn screening for cystic fibrosis: A prospective controlled study

Context: Newborn screening for cystic fibrosis (CF) is included in many routine programmes but current strategies have considerable drawbacks, such as false-positive tests, equivocal diagnosis and detection of carriers. Objective: To assess the test performance of two newborn screening strategies for CF. Design, setting and participants: In 2008...

Neonatale screening op cystische fibrose in Nederland (Newborn screening for cystic fibrosis in the Netherlands)

Do false positive test results for newborn screening for cystic fibrosis lead to long term parental anxiety?

Cystic fibrosis heelprick among a newborn population in the Netherlands: The CHOPIN-study

Abstract of the 32nd European Cystic Fibrosis Conference.

Cystic fibrosis hielprik onderzoek bij pasgeborenen in Nederland: De Chopin studie eindrapport