Omega-3 fatty acids in adipose tissue and risk of myocardial infarction: The EURAMIC study

Omega-3 fatty acids have potential antiatherogenic, antithrombotic, and antiarrhythmic properties, but their role in coronary heart disease remains controversial. To evaluate the association of omega-3 fatty acids in adipose tissue with the risk of myocardial infarction in men, a case-control study was conducted in eight European countries and...

Determinants of p,p'-dichlorodiphenyldichloroethane (DDE) concentration in adipose tissue in women from five European cities

To identify the determinants of p,p'-dichlorodiphenyldichloroethane (p,p'-DDE) in adipose tissue in subjects who participated in a cross- sectional study, we analyzed fatty acids, antioxidants, and p,p'-DDE in aspirates of adipose tissue of 328 postmenopausal women from 5 European countries. The overall mean of p,p'-DDE concentration was 1.66 μg...

Tissue stores of individual monounsaturated fatty acids and breast cancer: The EURAMIC study

Differences between plasma and adipose tissue biomarkers of carotenoids and tocopherols

Biomarkers of dietary exposure or nutritional status are sought actively to overcome limitations of traditional dietary methodology. We compared plasma and adipose tissue biomarkers for carotenoids and tocopherols. The data consisted of samples from 91 men and 122 women, ages 45-70 years, from the control group of the European Community...

Trans fatty acids in French fries, soups, and snacks from 14 European countries: The TRANSFAIR study

In the TRANSFAIR study, foods contributing to 95% of total fat intake were collected in 14 European countries. In addition to edible fats, dairy, meat, and bakery products some specific food items with relatively high amounts oftransfatty acids were found. French fried potatoes, both those from fast-food restaurants and those from the...

Adipose tissue omega-3 and omega-6 fatty acid content and breast cancer in the euramic study

The fatty acid content of adipose tissue in postmenopausal breast cancer cases and controls from five European countries in the European Community Multicenter Study on Antioxidants, Myocardial Infarction, and Cancer (EURAMIC) breast cancer study (1991-1992) was used to explore the hypothesis that fatty acids of the omega-3 family inhibit breast...

DDT (dicophane) and postmenopausal breast cancer in Europe: Case-control study

Objective: To examine any possible links between exposure to DDE (1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene), the persistent metabolite of the pesticide dicophane DDT), and breast cancer. Design: Multicentre study of exposure to DDE by measurement of adipose tissue aspirated from the buttocks. Laboratory measurements were conducted in a...

Tissue antioxidants and postmenopausal breast cancer: The European Community Multicentre Study on Antioxidants, Myocardial Infarction and Cancer of the Breast (EURAMIC)

Antioxidants may protect against free radical mediated carcinogenesis. Epidemiological studies have not confirmed this hypothesis for breast cancer, possibly because of methodological limitations. Time-integrated exposure of α-tocopherol and β-carotene in adipose tissue, and selenium in toenails was investigated in a case-control study among...

Association between beta-carotene and acute myocardial infarction depends on polyunsaturated fatty acid status: The EURAMIC study

Because antioxidants may play a role in the prevention of coronary heart disease by inhibiting the peroxidation of polyunsaturated fatty acids (PUFAs), the combined association of diet-derived antioxidants and PUFAs with acute myocardial infarction (MI) was investigated. This multicenter case- control study included 674 patients and 725 control...

Adipose tissue isomeric trans fatty acids and risk of myocardial infarction in nine countries: The EURAMIC study