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Fiehn, O. (author), Robertson, D. (author), Griffin, J. (author), van der Werf, M. (author), Nikolau, B. (author), Morrison, N. (author), Sumner, L.W. (author), Goodacre, R. (author), Hardy, N.W. (author), Taylor, C. (author), Fostel, J. (author), Kristal, B. (author), Kaddurah-Daouk, R. (author), Mendes, P. (author), van Ommen, B. (author), Lindon, J.C. (author), Sansone, S.-A. (author), TNO Kwaliteit van Leven (author)In 2005, the Metabolomics Standards Initiative has been formed. An outline and general introduction is provided to inform about the history, structure, working plan and intentions of this initiative. Comments on any of the suggested minimal reporting standards are welcome to be sent to the open email list Msi-workgroups-feedback@lists...article 2007
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- Sansone, S.A. (author), Fan, T. (author), Goodacre, R. (author), Griffin, J.L. (author), Hardy, N.W. (author), Kaddurah-Daouk, R. (author), Kristal, B.S. (author), Lindon, J. (author), Mendes, P. (author), Morrison, N. (author), Nikolau, B. (author), Robertson, D. (author), Summer, L. (author), Taylor, C. (author), van der Werf, M. (author), van Ommen, B. (author), Fiehn, O. (author), TNO Kwaliteit van Leven (author) article 2007
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Fiehn, O. (author), Kristal, B. (author), van Ommen, B. (author), Sumner, L.W. (author), Sansone, S.-A. (author), Taylor, C. (author), Hardy, N. (author), Kaddurah-Daouk, R. (author), TNO Kwaliteit van Leven (author)Metabolite concentrations in cellular systems are very much dependent on the physiological, environmental, and genetic status of an organism and are regarded as the ultimate result of cellular regulation, resulting in the visible phenotypes. Therefore, the comprehensive analysis of metabolite levels and fluxes renders a suitable tool for...article 2006
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TNO Preventie en Gezondheid (author), Lindahl, U. (author), Li, J.P. (author), Kusche-Gullberg, M. (author), Salmivirta, M. (author), Alaranta, S. (author), Veromaa, T. (author), Emeis, J. (author), Roberts, I. (author), Taylor, C. (author), Oreste, P. (author), Zoppetti, G. (author), Naggi, A. (author), Torri, G. (author), Casu, B. (author)Heparin remains a major drug in prevention of thromboembolic disease. Concerns related to its animal source have prompted search for heparin analogues. The anticoagulant activity of heparin depends on a specific pentasaccharide sequence that binds antithrombin. We report the generation of a product with antithrombin-binding, anticoagulant, and...article 2005