Active video games as a tool to prevent excessive weight gain in adolescents: Rationale, design and methods of a randomized controlled trial

Background: Excessive body weight, low physical activity and excessive sedentary time in youth are major public health concerns. A new generation of video games, the ones that require physical activity to play the games -i.e. active games- may be a promising alternative to traditional non-active games to promote physical activity and reduce...

Body size and growth in 0- to 4-year-old children and the relation to body size in primary school age

Excess weight in early life is believed to increase susceptibility to obesity, and in support of such theory, excess weight and fast weight gain in early childhood have been related to overweight later in life. The aim of this study was to review the literature on body size and growth in 0- to 4-year-old children and the association with body...

Accelerometers and Internet for physical activity promotion in youth? Feasibility and effectiveness of a minimal intervention [ISRCTN93896459]

Objective: To evaluate the feasibility and effectiveness of a 3-month minimal physical activity (PA) intervention in adolescents. Methods: A randomised controlled trial, including five secondary schools (n=87). In the 3-month intervention (Amsterdam, The Netherlands, 2005) adolescents were provided with a PAM accelerometer, coupled to a web...

Central fat mass versus peripheral fat and lean mass: Opposite (adverse versus favorable) associations with arterial stiffness? The Amsterdam growth and health longitudinal study

Central and peripheral fatness seem to confer opposite (i.e. adverse vs. protective) effects on cardiovascular risk, but how this occurs is not clear. In addition, the role of peripheral lean mass needs to be elucidated. We therefore investigated, in 336 (175 women) 36-yr-old and apparently healthy adults, the relationship between trunk fat,...

Lipid profiles reflecting high and low risk for coronary heart disease: Contribution of apolipoprotein E polymorphism and lifestyle

To elucidate the role of modifiable factors and the apolipoprotein E polymorphism in explaining lipid profiles reflecting low, average and high risk for coronary heart disease, we selected subjects from a large population-based study. Subjects with low total cholesterol (TC) (< 15th percentile) and high HDL-cholesterol levels (> 85th percentile)...

Exogene determinanten: leefstijl : voeding

Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls

Autoantibodies against oxidized low-density lipoprotein (LDL) have been reported to be associated with atherosclerosis. However, data are not consistent. We compared the titres of autoantibodies to malondialdehyde-modified LDL in three groups, a case group with angiographically documented severe coronary stenosis (> 80% stenosis in at least 1...

Fat and female fecundity: Prospective study of effect of body fat distribution on conception rates