Searched for: author:"Schinkel, J."
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Spaan, S. (author), Tromp, P. (author), Lucas Luijckx, N. (author), de Weerd, H. (author), ten Brug, B. (author), Franken, R. (author), Schinkel, J. (author)
report 2021
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Kuijpers, E. (author), le Feber, M. (author), Schinkel, J. (author), Pronk, A. (author)
Beroepsziekten hebben een grate impact op onze maatschappij. Dat moet en kan anders. Met de Virtual Occupational Hygiene Assistant (VOHA) werkt TNO aan effectievere preventie ervan. Deze techniek maakt het mogelijk om continu en preciezer blootstellingen in de werkomgeving te meten. En maakt zo gerichter en directer ingrijpen mogelijk. Vakmedianet
article 2021
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Goede, H.A. (author), McNally, K. (author), Gorce, J.P. (author), Marquart, H. (author), Warren, N.D. (author), Fransman, W. (author), Tischer, M. (author), Schinkel, J. (author)
This article describes the development of a mechanistic model for underpinning the dermal Advanced REACH Tool (dART), an extension of the existing ART model and its software platform. It was developed for hand exposure to low volatile liquids (vapour pressure ≤ 10 Pa at 20°C) including solids-in-liquid products. The model is based on an existing...
article 2019
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Schinkel, J. (author), Heerderik, D. (author), Helsloot, I. (author), Kraaijenbrink, S. (author), Vis, J. (author)
In veel situaties is momenteel onduidelijk wat de blootstelling aan asbest (door inhalatie) werkelijk is, en daarmee wat de bijbehorende gezondheidsrisico’s zijn. Hierdoor is het dus veelal niet mogelijk om vast te stellen wat proportionele veiligheidsmaatregelen zijn.
report 2019
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McNally, K. (author), Gorce, J.P. (author), Goede, H.A. (author), Schinkel, J. (author), Warren, N. (author)
The dermal Advanced REACH Tool (dART) is a Tier 2 exposure modelling tool currently in development for estimating dermal exposure to the hands (mg min-1) for non-volatile liquid and solids-in-liquid products. The dART builds upon the existing ART framework and describes three mass transport processes [deposition (Dhands), direct emission and...
article 2019
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Savic, N. (author), Gasic, B. (author), Schinkel, J. (author), Vernez, D. (author)
The Advanced REACH Tool (ART) is the most sophisticated tool used for evaluating exposure levels under the European Union's Registration, Evaluation, Authorisation and restriction of CHemicals (REACH) regulations. ART provides estimates at different percentiles of exposure and within different confidence intervals (CIs). However, its performance...
article 2018
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Spaan, S. (author), Schinkel, J. (author)
report 2018
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Voogd, E. (author), Schinkel, J. (author)
Het verwijderen van asbest en asbesthoudende materialen is sterk gereguleerd in Nederland, om te borgen dat (gezondheids)risico’s voor mens en milieu beperkt blijven. Er zijn echter signalen van uit de branche dat deze regulering onnodig complex zou zijn. Verder zijn er signalen dat de kosten van asbestverwijderingen hoger zouden zijn dan...
report 2018
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Spaan, S. (author), Schinkel, J. (author), Tromp, P. (author)
report 2017
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Marquart, H. (author), Franken, R. (author), Goede, H. (author), Fransman, W. (author), Schinkel, J. (author)
The ECETOC TRA model (presently version 3.1) is often used to estimate worker inhalation and dermal exposure in regulatory risk assessment. The dermal model in ECETOC TRA has not yet been validated by comparison with independent measured exposure levels. This was the goal of the present study. Measured exposure levels and relevant contextual...
article 2017
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Spaan, S. (author), Tromp, P. (author), Diks, M. (author), Krystek, P. (author), Schinkel, J. (author)
report 2017
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Schinkel, J. (author)
report 2017
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Spaan, S. (author), den Boeft, K. (author), Tromp, P. (author), Tempelman, J. (author), Schinkel, J. (author)
report 2016
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Schinkel, J. (author), Fransman, W. (author), McDonnell, P.E. (author), Entink, R.K. (author), Tielemans, E. (author), Kromhout, H. (author)
Objectives: The aim of this study was to assess the reliability of the Advanced REACH Tool (ART) by (i) studying interassessor agreement of the resulting exposure estimates generated by the ART mechanistic model, (ii) studying interassessor agreement per model parameters of the ART mechanistic model, (iii) investigating assessor characteristics...
article 2014
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McNally, K. (author), Warren, N. (author), Fransman, W. (author), Entink, R.K. (author), Schinkel, J. (author), Van Tongeren, M. (author), Cherrie, J.W. (author), Kromhout, H. (author), Schneider, T. (author), Tielemans, E. (author)
This paper describes a Bayesian model for the assessment of inhalation exposures in an occupational setting; the methodology underpins a freely available web-based application for exposure assessment, the Advanced REACH Tool (ART). The ART is a higher tier exposure tool that combines disparate sources of information within a Bayesian statistical...
article 2014
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Schinkel, J. (author), Richie, P. (author), Goede, H. (author), Fransman, W. (author), van Tongeren, M. (author), Cherrie, J.W. (author), Tielemans, E. (author), Kromhout, H. (author), Warren, N. (author)
This article describes the structure, functionalities, and content of the Advanced REACH Tool (ART) exposure database (version 1.5). The incorporation of the exposure database into ART allows users who do not have their own measurement data for their exposure scenario, to update the exposure estimates produced by the mechanistic model using...
article 2013
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Koppisch, D. (author), Schinkel, J. (author), Gabriel, S. (author), Fransman, W. (author), Tielemans, E. (author)
Objectives: This paper explores the usefulness of the exposure database MEGA for model validation and evaluates the capability of two Stoffenmanager model equations (i.e. handling of powders/granules and machining) to estimate workers exposure to inhalable dust. Methods: For the task groups, ‘handling of powders and granules’ (handling) and ...
article 2012
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Gerritsen-Ebben, R. (author), Glass, R. (author), Goede, H. (author), Schinkel, J. (author), Spaan, S. (author), Charistou, A. (author), Arapaki, N. (author), Machera, K. (author), Kennedy, M. (author), Hart, A. (author)
article 2012
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Marquart, H. (author), Schneider, T. (author), Goede, H. (author), Tischer, M. (author), Schinkel, J. (author), Warren, N. (author), Fransman, W. (author), Spaan, S. (author), van Tongeren, M. (author), Kromhout, H. (author), Tielemans, E. (author), Cherrie, J.W. (author), TNO Kwaliteit van Leven (author)
There is a large variety of activities in workplaces that can lead to emission of substances. Coding systems based on determinants of emission have so far not been developed. In this paper, a system of Activity Classes and Activity Subclasses is proposed for categorizing activities involving chemical use. Activity Classes share their so-called ...
article 2011
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van Tongeren, M. (author), Fransman, W. (author), Spankie, S. (author), Tischer, M. (author), Brouwer, D. (author), Schinkel, J. (author), Cherrie, J.W. (author), Tielemans, E. (author)
The Advanced REACH Tool (ART) is an exposure assessment tool that combines mechanistically modelled inhalation exposure estimates with available exposure data using a Bayesian approach. The mechanistic model is based on nine independent principal modifying factors (MF). One of these MF is the substance emission potential, which addresses the...
article 2011
Searched for: author:"Schinkel, J."
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