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Koushik, A. (author), Spiegelman, D. (author), Albanes, D. (author), Anderson, K.E. (author), Bernstein, L. (author), van den Brandt, P.A. (author), Bergkvist, L. (author), English, D.R. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Genkinger, J.M. (author), Giles, G.G. (author), Goldbohm, R.A. (author), Horn-Ross, P.L. (author), Männistö, S. (author), McCullough, M.L. (author), Millen, A.E. (author), Miller, A.B. (author), Robien, K. (author), Rohan, T.E. (author), Schatzkin, A. (author), Shikany, J.M. (author), Stolzenberg-Solomon, R.Z. (author), Willett, W.C. (author), Wolk, A. (author), Ziegler, R.G. (author), Smith-Warner, S.A. (author)Fruit and vegetable intake may protect against pancreatic cancer, since fruits and vegetables are rich in potentially cancer-preventive nutrients. Most case-control studies have found inverse associations between fruit and vegetable intake and pancreatic cancer risk, although bias due to reporting error cannot be ruled out. In most prospective...article 2012
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Zhang, X. (author), Albanes, D. (author), Beeson, W.L. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Flood, A. (author), Freudenheim, J.L. (author), Giovannucci, E.L. (author), Goldbohm, R.A. (author), Jaceldo-Siegl, K. (author), Jacobs, E.J. (author), Krogh, V. (author), Larsson, S.C. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Robien, K. (author), Rohan, T.E. (author), Schatzkin, A. (author), Sieri, S. (author), Spiegelman, D. (author), Virtamo, J. (author), Wolk, A. (author), Willett, W.C. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)BackgroundThe relationships between coffee, tea, and sugar-sweetened carbonated soft drink consumption and colon cancer risk remain unresolved. MethodsWe investigated prospectively the association between coffee, tea, and sugar-sweetened carbonated soft drink consumption and colon cancer risk in a pooled analysis of primary data from 13 cohort...article 2010
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Kim, D.H. (author), Smith-Warner, S.A. (author), Spiegelman, D. (author), Yaun, S.S. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Graham, S. (author), Harnack, L. (author), Jacobs, E.J. (author), Leitzmann, M. (author), Mannisto, S. (author), Miller, A.B. (author), Potter, J.D. (author), Rohan, T.E. (author), Schatzkin, A. (author), Speizer, F.E. (author), Stevens, V.L. (author), Stolzenberg-Solomon, R. (author), Terry, P. (author), Toniolo, P. (author), Weijenberg, M.P. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Hunter, D.J. (author), TNO Kwaliteit van Leven (author)Objective: Studies of folate intake and colorectal cancer risk have been inconsistent. We examined the relation with colon cancer risk in a series of 13 prospective studies. Methods: Study-and sex-specific relative risks (RRs) were estimated from the primary data using Cox proportional hazards models and then pooled using a random-effects model....article 2010
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Park, Y. (author), Spiegelman, D. (author), Hunter, D.J. (author), Albanes, D. (author), Bergkvist, L. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Kato, I. (author), Krogh, V. (author), Leitzmann, M.F. (author), Limburg, P.J. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Shore, R. (author), Sieri, S. (author), Stampfer, M.J. (author), Virtamo, J. (author), Weijenberg, M. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Objective: To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer. Methods: Using the primary data from 13 cohort studies, we estimated study-and sex-specific relative risks (RR) with Cox proportional hazards models and subsequently pooled RRs using a random effects model. Results: Among 676,141 men and...article 2010
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Männistö, S. (author), Yaun, S.S. (author), Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.O. (author), Albanes, D. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cerhan, J.R. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Virtamo, J. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Dietary carotenoids have been hypothesized to protect against epithelial cancers. The authors analyzed the associations between intakes of specific carotenoids (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein + zeaxanthin, and lycopene) and risk of colorectal cancer using the primary data from 11 cohort studies carried out in North...article 2007
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Koushik, A. (author), Hunter, D.J. (author), Spiegelman, D. (author), Beeson, W.L. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Calle, E.E. (author), Cho, E. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E.L. (author), Goldbohm, R.A. (author), Harnack, L. (author), Jacobs Jr., D.R. (author), Kato, I. (author), Krogh, V. (author), Larsson, S.C. (author), Leitzmann, M.F. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Pietinen, P. (author), Rohan, T.E. (author), Schatzkin, A. (author), Sieri, S. (author), Virtanen, M.J. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Background Fruit and vegetable intakes have been associated with a reduced risk of colon cancer; however, in more recent studies associations have been less consistent. Statistical power to examine associations by colon site has been limited in previous studies. Methods Fruit and vegetable intakes in relation to colon cancer risk were examined...article 2007
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Smith-Warner, S.A. (author), Spiegelman, D. (author), Ritz, J. (author), Albanes, D. (author), Beeson, W.L. (author), Bernstein, L. (author), Berrino, F. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cho, E. (author), Colditz, G.A. (author), Folsom, A.R. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Graham, S. (author), Harnack, L. (author), Horn-Ross, P.L. (author), Krogh, V. (author), Leitzmann, M.F. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Schatzkin, A. (author), Shore, R. (author), Virtanen, M. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Hunter, D.J. (author), TNO Kwaliteit van Leven (author)With the growing number of epidemiologic publications on the relation between dietary factors and cancer risk, pooled analyses that summarize results from multiple studies are becoming more common. Here, the authors describe the methods being used to summarize data on diet-cancer associations within the ongoing Pooling Project of Prospective...article 2006
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Koushik, A. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Larsson, S.C. (author), Leitzmann, M. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Ross, J.A. (author), Schatzkin, A. (author), Schouten, L.J. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Carotenoids, found in fruits and vegetables, have the potential to protect against cancer because of their properties, including their functions as precursors to vitamin A and as antioxidants. We examined the associations between intakes of α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin and lycopene and the risk of invasive...article 2006
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A pooled analysis of 12 cohort studies of dietary fat, cholesterol and egg intake and ovarian cancerGenkinger, J.M. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Beeson, W.L. (author), Buring, J.E. (author), Colditz, G.A. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Koenig, K.L. (author), Larsson, S.C. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Ross, J.A. (author), Schatzkin, A. (author), Schouten, L.J. (author), Smit, E. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven TNO Voeding (author)Fat and cholesterol are theorized to promote ovarian carcinogenesis by increasing circulating estrogen levels. Although case-control studies have reported positive associations between total and saturated fat intake and ovarian cancer risk, two cohort studies have observed null associations. Dietary cholesterol and eggs have been positively...article 2006
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TNO Kwaliteit van Leven TNO Voeding (author), Genkinger, J.M. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Harnack, L. (author), Hankinson, S.E. (author), Larsson, S.C. (author), Leitzmann, M. (author), McCullough, M.L. (author), Marshall, J. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Schatzkin, A. (author), Schouten, L.J. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author)Alcohol has been hypothesized to promote ovarian carcinogenesis by its potential to increase circulating levels of estrogen and other hormones; through its oxidation byproduct, acetaldehyde, which may act as a cocarcinogen; and by depletion of folate and other nutrients. Case-control and cohort studies have reported conflicting results relating...article 2006
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Park, Y. (author), Hunter, D.J. (author), Spiegelman, D. (author), Bergkvist, L. (author), Berrino, F. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Graham, S. (author), Harnack, L. (author), Hartman, A.M. (author), Jacobs, D.R. (author), Kato, I. (author), Krogh, V. (author), Leitzmann, M.F. (author), McCullough, M.L. (author), Miller, A.B. (author), Pietinen, P. (author), Rohan, T.E. (author), Schatzkin, A. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Context: Inconsistent findings from observational studies have continued the controversy over the effects of dietary fiber on colorectal cancer. Objective: To evaluate the association between dietary fiber intake and risk of colorectal cancer. Design, Setting, and Participants: From 13 prospective cohort studies included in the Pooling Project...article 2005
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Koushik, A. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Arslan, A.A. (author), Beeson, W.L. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cerhan, J.R. (author), Colditz, G.A. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Genkinger, J.M. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Koenig, K.L. (author), Larsson, S.C. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Patel, A. (author), Rohan, T.E. (author), Schatzkin, A. (author), Smit, E. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Because fruits and vegetables are rich in bioactive compounds with potential cancer-preventive actions, increased consumption may reduce the risk of ovarian cancer. Evidence on the association between fruit and vegetable intake and ovarian cancer risk has not been consistent. We analyzed and pooled the primary data from 12 prospective studies in...article 2005