Searched for: author:"Roeselers, G."
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van Nieuwenhuijzen, E.J. (author), Houbraken, J.A.M.P. (author), Punt, P.J. (author), Roeselers, G. (author), Adan, O.C.G. (author), Samson, A. (author)
Background: Biofinished wood is considered to be a decorative and protective material for outdoor constructions, showing advantages compared to traditional treated wood in terms of sustainability and self-repair. Natural dark wood staining fungi are essential to biofinish formation on wood. Although all sorts of outdoor situated timber are...
article 2017
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Botschuijver, S. (author), Roeselers, G. (author), Levin, E. (author), Jonkers, D.M. (author), Welting, O. (author), Heinsbroek, S.E.M. (author), de Weerd, H.H. (author), Boekhout, T. (author), Fornai, M. (author), Masclee, A.A. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), Seppen, J. (author), van den Wijngaard, R.M. (author)
Background & Aims Visceral hypersensitivity is one feature of irritable bowel syndrome (IBS). Bacterial dysbiosis might be involved in the activation of nociceptive sensory pathways, but there have been few studies of the role of the mycobiome (the fungal microbiome) in the development of IBS. We analyzed intestinal mycobiomes of patients with...
article 2017
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Fiamoncini, J. (author), Yiorkas, A.M. (author), Gedrich, K. (author), Rundle, M. (author), Alsters, S.I. (author), Roeselers, G. (author), van den Broek, T.J. (author), Clavel, T. (author), Lagkouvardos, I. (author), Wopereis, S. (author), Frost, G. (author), van Ommen, B. (author), Blakemore, A.I. (author), Daniel, H. (author)
Bile acids (BA) are signaling molecules with a wide range of biological effects, also identified among the most responsive plasma metabolites in the postprandial state. We here describe this response to different dietary challenges and report on key determinants linked to its interindividual variability. Healthy men and women (n = 72, 62 ± 8 yr,...
article 2017
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Goverse, G. (author), Molenaar, R. (author), MacIa, L. (author), Tan, J. (author), Erkelens, M.N. (author), Konijn, T. (author), Knippenberg, M. (author), Cook, E.C.L. (author), Hanekamp, D. (author), Veldhoen, M. (author), Hartog, A. (author), Roeselers, G. (author), MacKay, C.R. (author), Mebius, R.E. (author)
The gastrointestinal tract is continuously exposed to many environmental factors that influence intestinal epithelial cells and the underlying mucosal immune system. In this article, we demonstrate that dietary fiber and short chain fatty acids (SCFAs) induced the expression of the Vitamin A-converting enzyme RALDH1 in intestinal epithelial...
article 2017
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van der Wielen, P.W.J.J. (author), Bakker, G. (author), Atsma, A. (author), Lut, M. (author), Roeselers, G. (author), de Graaf, B. (author)
The objective of our study was to explore microbiological parameters that are suitable as indicators for regrowth in distribution systems that receive unchlorinated drinking water in the Netherlands. Treated water and distributed water at two locations in the distribution system of 28 treatment plants were analyzed for a range of biological...
article 2016
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de Souza, C.B. (author), Roeselers, G. (author), Troost, F. (author), Jonkers, D. (author), Koenen, M.E. (author), Venema, K. (author)
article 2015
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Lukovac, S. (author), Roeselers, G. (author)
When it comes to studying the effect of food bioactives on gut health, one of the essential steps that needs to be assessed is characterizing specific effects of the bioactives on the physical barrier of the lumen, the gastrointestinal tissue. In addition to studying the effects on transport function (e.g. by using Ussing chambers or cell...
bookPart 2015
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Roeselers, G. (author), Coolen, J. (author), van der Wielen, P.W. (author), Jaspers, M.C. (author), Atsma, A. (author), de Graaf, B. (author), Schuren, F. (author)
In this study, we collected water from different locations in 32 drinking water distribution networks in the Netherlands and analysed the spatial and temporal variation in microbial community composition by high-throughput sequencing of 16S rRNA gene amplicons. We observed that microbial community compositions of raw source and processed water...
article 2015
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Paauw, A. (author), Jonker, D. (author), Roeselers, G. (author), Heng, J.M.E. (author), Mars-Groenendijk, R.H. (author), Trip, H. (author), Molhoek, E.M. (author), Jansen, H.J. (author), van der Plas, J. (author), de Jong, A.L. (author), Majchrzykiewicz-Koehorst, J.A. (author), Speksnijder, A.G.C.L. (author)
E. coli-. Shigella species are a cryptic group of bacteria in which the Shigella species are distributed within the phylogenetic tree of E. coli. The nomenclature is historically based and the discrimination of these genera developed as a result of the epidemiological need to identify the cause of shigellosis, a severe disease caused by Shigella...
article 2015
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Lukovac, S. (author), Belzer, C. (author), Pellis, L. (author), Keijser, B.J. (author), de Vos, W.M. (author), Montijn, R.C. (author), Roeselers, G. (author)
The gut microbiota is essential for numerous aspects of human health. However, the underlying mechanisms of many host-microbiota interactions remain unclear. The aim of this study was to characterize effects of the microbiota on host epithelium using a novel ex vivo model based on mouse ileal organoids. We have explored the transcriptional...
article 2014
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Kelder, T. (author), Stroeve, J.H.M. (author), Bijlsma, S. (author), Radonjic, M. (author), Roeselers, G. (author)
BACKGROUND: Recent evidence suggests that the gut microbiota plays an important role in human metabolism and energy homeostasis and is therefore a relevant factor in the assessment of metabolic health and flexibility. Understanding of these host–microbiome interactions aids the design of nutritional strategies that act via modulation of the...
article 2014
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Bussolo de Souza, C. (author), Roeselers, G. (author), Troost, F. (author), Jonkers, D. (author), Koenen, M.E. (author), Venema, K. (author)
Obesity is currently a worldwide epidemic that has serious consequences for health. It has been suggested that the gut microbiota can influence body weight, e.g., by producing short-chain fatty acids (SCFA), which are substrates for the host and induce the release of satiety hormones (e.g., PYY). To test the potential prebiotic effect of cassava...
article 2014
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Belzer, C. (author), Gerber, G.K. (author), Roeselers, G. (author), Delaney, M. (author), DuBois, A. (author), Liu, Q. (author), Belavusava, V. (author), Yeliseyev, V. (author), Houseman, A. (author), Onderdonk, A. (author), Cavanaugh, C. (author), Bry, L. (author)
Longitudinal studies of the microbiota are important for discovering changes in microbial communities that affect the host. The complexity of these ecosystems requires rigorous integrated experimental and computational methods to identify temporal signatures that promote physiologic or pathophysiologic responses in vivo. Employing a murine model...
article 2014
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Aguirre, M. (author), Jonkers, D.M.A.E. (author), Troost, F.J. (author), Roeselers, G. (author), Venema, K. (author)
The aim of this study was to investigate the effect of galacto-oligosaccharides, lactulose, apple fiber and sugar beet pectin on the composition and activity of human colonic microbiota of lean and obese healthy subjects using an in vitro model of the proximal colon: TIM-2. Substrate fermentation was assessed by measuring the production of short...
article 2014
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van de Vossenberg, J. (author), Woebken, D. (author), Maalcke, W.J. (author), Wessels, H.J.C.T. (author), Dutilh, B.E. (author), Kartal, B. (author), Janssen-Megens, E.M. (author), Roeselers, G. (author), Yan, J. (author), Speth, D. (author), Gloerich, J. (author), Geerts, W. (author), van der Biezen, E. (author), Pluk, W. (author), Francoijs, K.-J. (author), Russ, L. (author), Lam, P. (author), Malfatti, S.A. (author), Tringe, S.G. (author), Haaijer, S.C.M. (author), op den Camp, H.J.M. (author), Stunnenberg, H.G. (author), Amann, R. (author), Kuypers, M.M.M. (author), Jetten, M.S.M. (author)
Anaerobic ammonium-oxidizing (anammox) bacteria are responsible for a significant portion of the loss of fixed nitrogen from the oceans, making them important players in the global nitrogen cycle. To date, marine anammox bacteria found in marine water columns and sediments worldwide belong almost exclusively to the 'Candidatus Scalindua' species...
article 2013
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Roeselers, G. (author), Ponomarenko, M. (author), Lukovac, S. (author), Wortelboer, H.M. (author)
It is increasingly apparent that the microbial ecosystems in the mammalian gastrointestinal tract play an intricate role in health and disease. There is a growing interest in the development of targeted strategies for modulating health through the modification of these microbiota. Ecologists are faced with the challenge of understanding the...
article 2013
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Coolen, J.P.M. (author), Sjödin, A. (author), Maraha, B. (author), Hajer, G.F. (author), Forsman, M. (author), Verspui, E. (author), Frenay, H.M.E. (author), Notermans, D.W. (author), de Vries, M.C. (author), Reubsaet, F.A.G. (author), Paauw, A. (author), Roeselers, G. (author)
Francisella tularensis is a facultative intracellular bacterium in the class Gammaproteobacteria. This strain is of interest because it is the etiologic agent of tularemia and a highly virulent category A biothreat agent. Here we describe the draft genome sequence and annotation of Francisella tularensis subsp. holarctica BD11-00177, isolated...
article 2013
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Zhao, Y. (author), Caspers, M.P.M. (author), Metselaar, K.I. (author), de Boer, P. (author), Roeselers, G. (author), Moezelaar, R. (author), Groot, M.N. (author), Montijn, R.C. (author), Abee, T. (author), Korta, R. (author)
One of the major concerns in the production of dairy concentrates is the risk of contamination by heat-resistant spores from thermophilic bacteria. In order to acquire more insight in the composition of microbial communities occurring in the dairy concentrate industry, a bar-coded 16S amplicon sequencing analysis was carried out on milk, final...
article 2013
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Maraha, B. (author), Hajer, G.F. (author), Sjödin, A. (author), Forsman, M. (author), Paauw, A. (author), Roeselers, G. (author), Verspui, E. (author), Frenay, H.M.E. (author), Notermans, D.W. (author), de Vries, M.C. (author), Reubsaet, F.A.G. (author)
We report here the first case of indigenous tularemia detected inTheNetherlands, a nonendemic country, since 1953.Whole genome DNAsequence analysis assigned the isolate BD11-00177 to the genomic group B.FTNF002-00,which previously has been exclusively reported from Spain, France, Italy, Switzerland, and Germany. The patient had not been abroad...
article 2013
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Roeselers, G. (author), Bouwman, J. (author), Venema, K. (author), Montijn, R. (author)
The mammalian gastrointestinal tract (GIT) harbors microorganisms (the microbiota) of vast phylogentic, genomic, and metabolic diversity, and recent years have seen a rapid development in the techniques for studying these complex microbial ecosystems. It is increasingly apparent that the GIT microbiota plays an intricate role in host health and...
article 2012
Searched for: author:"Roeselers, G."
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