Searched for: author%3A%22Pasman%2C+W.J.%22
(1 - 20 of 35)

Pages

document
de Hoogh, I.M. (author), Pasman, W.J. (author), Boorsma, A. (author), van Ommen, B. (author), Wopereis, S. (author)
A type 2 diabetes mellitus (T2DM) subtyping method that determines the T2DM phenotype based on an extended oral glucose tolerance test is proposed. It assigns participants to one of seven subtypes according to their β-cell function and the presence of hepatic and/or muscle insulin resistance. The effectiveness of this subtyping approach and...
article 2022
document
de Hoogh, I.M. (author), Oosterman, J.E. (author), Otten, W. (author), Krijger, A.M. (author), Berbée-Zadelaar, S. (author), Pasman, W.J. (author), van Ommen, B. (author), Pijl, H. (author), Wopereis, S. (author)
Although lifestyle interventions can lead to diabetes remission, it is unclear to what extent type 2 diabetes (T2D) remission alters or improves the underlying pathophysiology of the disease. Here, we assess the effects of a lifestyle intervention on T2D reversal or remission and the effects on the underlying pathology. In a Dutch primary care...
article 2021
document
Memelink, R.G. (author), Pasman, W.J. (author), Bongers, A. (author), Tump, A. (author), van Ginkel, A. (author), Tromp, W. (author), Wopereis, S. (author), Verlaan, S. (author), den Bosch, J.V.V. (author), Weijs, P.J.M. (author)
Background: Weight loss is key to treatment of older adults with obesity and type 2 diabetes, but also a risk for muscle mass loss. This study investigated whether a whey protein drink enriched with leucine and vitamin D could preserve muscle mass and improve glycemic control during combined lifestyle intervention in this population. Methods:...
article 2021
document
Coert, R.M.H. (author), Timmis, J.K. (author), Boorsma, A (author), Pasman, W.J. (author)
Background: Conventional clinical trials are essential for generating high-quality evidence by measuring the efficacy of interventions in rigorously controlled clinical environments. However, their execution can be expensive and time-consuming. In addition, clinical trials face several logistical challenges regarding the identification,...
article 2021
document
Haji, M. (author), Memelink, R.G. (author), Brandt, B.W. (author), Buijs, M.J. (author), Pasman, W.J. (author), de Vogel-Bosch, J. (author), Wopereis, S. (author), Zaura, E. (author), Weijs, P.J.M. (author)
Rationale: While combined lifestyle interventions have multiple health benefits, their impact on the oral microbiome is not known. We explored the effects of a lifestyle intervention including protein drink on the oral microbiome in older adults with obesity and type 2 diabetes (T2D). Methods: In a post-hoc analysis of the PROBE study, 87...
article 2021
document
Krone, T. (author), Boessen, R. (author), Bijlsma, S. (author), van Stokkum, R. (author), Clabbers, N.D.S. (author), Pasman, W.J. (author)
Background. N-of-1 designs gain popularity in nutritional research because of the improving technological possibilities, practical applicability and promise of increased accuracy and sensitivity, especially in the field of personalized nutrition. This move asks for a search of applicable statistical methods. Objective. To demonstrate the...
article 2020
document
Hoevenaars, F.P.M. (author), Berendsen, C.M.M. (author), Pasman, W.J. (author), van den Broek, T.J. (author), Barrat, E. (author), de Hoogh, I.M. (author), Wopereis, S. (author)
In public health initiatives, generic nutrition advice (GNA) from national guidelines has a limited effect on food-intake improvement. Personalized nutrition advice (PNA) may enable dietary behavior change. A monocentric, randomized, parallel, controlled clinical trial was performed in males (n = 55) and females (n = 100) aged 25 to 70 years....
article 2020
document
Pasman, W.J. (author), Memelink, R.G. (author), den Bosch, J.V.V. (author), Begieneman, M.P.V. (author), van den Brink, W.J. (author), Weijs, P.J.M. (author), Wopereis, S. (author)
Background: Recent research showed that subtypes of patients with type 2 diabetes may differ in response to lifestyle interventions based on their organ-specific insulin resistance (IR). (2) Methods: 123 Subjects with type 2 diabetes were randomized into 13-week lifestyle intervention, receiving either an enriched protein drink (protein+) or an...
article 2020
document
Bellmann, S. (author), Krishnan, S. (author), de Graaf, A. (author), de Ligt, R.A. (author), Pasman, W.J. (author), Minekus, M. (author), Havenaar, R. (author)
The expected increase of global obesity prevalence makes it necessary to have information about the effects of meal intakes on the feeling of appetite. Because human clinical studies are time and cost intensive, there is a need for a reliable alternative. The aim of this study was to develop and evaluate an in vitro-in silico technology to...
article 2019
document
Doets, E.L. (author), de Hoogh, I.M. (author), Holthuysen, N. (author), Wopereis, S. (author), Verain, M.C.D. (author), van den Puttelaar, J. (author), Hogenelst, K. (author), Boorsma, A. (author), Bouwman, E.P. (author), Timmer, M. (author), Pasman, W.J. (author), van Erk, M. (author), Reinders, M.J. (author)
The aim of this explorative study is to evaluate whether personalized compared to generic lifestyle advice improves wellbeing in a senior population. We conducted a nine-week single-blind randomized controlled trial including 59 participants (age 67.7 ± 4.8 years) from Wageningen and its surrounding areas in the Netherlands. Three times during...
article 2019
document
Pasman, W.J. (author), Hendriks, H.F.J. (author), Minekus, M.M. (author), de Ligt, R.A.F. (author), Scholtes-Timmerman, M.J. (author), Clabbers, N.D.S. (author), Leonards, N.M. (author), Johnson, J. (author), Bellmann, S. (author)
Background: Appetite regulating properties of foods are usually investigated under laboratory conditions, whereas in real life, foods are consumed under at home conditions. The objective of this study was to compare the acute effects of breakfasts when tested in a laboratory condition and in an at home condition. Appetite regulating properties...
article 2018
document
Vlaming, M.L. (author), van Duijn, E. (author), Dillingh, M.R. (author), Brands, R. (author), Windhorst, A.D. (author), Hendrikse, N.H. (author), Bosgra, S. (author), Burggraaf, J. (author), de Koning, M.C. (author), Fidder, A. (author), Mocking, J.A. (author), Sandman, H. (author), de Ligt, R.A. (author), Fabriek, B.O. (author), Pasman, W.J. (author), Seinen, W. (author), Alves, T. (author), Carrondo, M. (author), Peixoto, C. (author), Peeters, P.A. (author), Vaes, W.H. (author)
Preclinical development of new biological entities (NBEs), such as human protein therapeutics, requires considerable expenditure of time and costs. Poor prediction of pharmacokinetics in humans further reduces net efficiency. In this study, we show for the first time that pharmacokinetic data of NBEs in humans can be successfully obtained early...
article 2015
document
Souverein, O.W. (author), de Vries, J.H.M. (author), Freese, R. (author), Watzl, B. (author), Bub, A. (author), III Miller, E.R., (author), Castenmiller, J.J.M. (author), Pasman, W.J. (author), van het Hof, K. (author), Chopra, M. (author), Karlsen, A. (author), Dragsted, L.O. (author), Winkels, R. (author), Itsiopoulos, C. (author), Brazionis, L. (author), O'Dea, K. (author), van Loo-Bouwman, C.A. (author), Naber, T.H.J. (author), van der Voet, H. (author), Boshuizen, H.C. (author)
Fruit and vegetable consumption produces changes in several biomarkers in blood. The present study aimed to examine the dose-response curve between fruit and vegetable consumption and carotenoid (alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein and zeaxanthin), folate and vitamin C concentrations. Furthermore, a prediction...
article 2015
document
van Schalkwijk, D.B. (author), Pasman, W.J. (author), Hendriks, H.F.J. (author), Verheij, E.R. (author), Rubingh, C.M. (author), van Bochove, K. (author), Vaes, W.H.J. (author), Adiels, M. (author), Freidig, A.P. (author), de Graaf, A.A. (author)
Dietary medium chain fatty acids (MCFA) and linoleic acid follow different metabolic routes, and linoleic acid activates PPAR receptors. Both these mechanisms may modify lipoprotein and fatty acid metabolism after dietary intervention. Our objective was to investigate how dietary MCFA and linoleic acid supplementation and body fat distribution...
article 2014
document
Pasman, W.J. (author), van Erk, M.J. (author), Klöpping, W.A.A. (author), Pellis, L. (author), Wopereis, S. (author), Bijlsma, S. (author), Hendriks, H.F.J. (author), Kardinaal, A.F.M. (author)
We aimed to explore whether vegetable consumption according to guidelines has beneficial health effects determined with classical biomarkers and nutrigenomics technologies. Fifteen lean (age 36 ± 7 years; BMI 23.4 ± 1.7 kg m-2) and 17 obese (age 40 ± 6 years; BMI 30.3 ± 2.4 kg m-2) men consumed 50- or 200-g vegetables for 4 weeks in a randomized...
article 2013
document
Visscher, T.L.S. (author), Nicolaou, M. (author), Pasman, W.J. (author), Goossens, G.H. (author), van Mil, E.G.A.H. (author), van Spanje, M.C. (author), Mariman, E.C.M. (author)
article 2012
document
TNO Kwaliteit van Leven (author), Radonjic, M. (author), van Erk, M.J. (author), Pasman, W.J. (author), Wortelboer, H.M. (author), Hendriks, H.F.J. (author), van Ommen, B. (author)
Combination of decreased energy expenditure and increased food intake results in fat accumulation either in the abdominal site (upper body obesity, UBO) or on the hips (lower body obesity, LBO). In this study, we used microarray gene expression profiling of adipose tissue biopsies to investigate the effect of body fat distribution on the...
article 2009
document
TNO Kwaliteit van Leven (author), van Erk, M.J. (author), Pasman, W.J. (author), Wortelboer, H.M. (author), van Ommen, B. (author), Hendriks, H.F.J. (author)
The goal of this study was to investigate the effect of a short-term nutritional intervention on gene expression in adipose tissue from lean and overweight subjects. Gene expression profiles were measured after consumption of an intervention spread (increased levels of polyunsaturated fatty acids, conjugated linoleic acid and medium chain...
article 2008
document
TNO Kwaliteit van Leven (author), Pasman, W.J. (author), Heimerikx, J. (author), Rubingh, C.M. (author), van den Berg, R. (author), O'Shea, M. (author), Gambelli, L. (author), Hendriks, H.F.J. (author), Einerhand, A.W.C. (author), Scott, C. (author), Keizer, H.G. (author), Mennen, L.I. (author)
Appetite suppressants may be one strategy in the fight against obesity. This study evaluated whether Korean pine nut free fatty acids (FFA) and triglycerides (TG) work as an appetite suppressant. Korean pine nut FFA were evaluated in STC-1 cell culture for their ability to increase cholecystokinin (CCK-8) secretion vs. several other dietary...
article 2008
document
Hendriks, H.F.J. (author), Bakker, G.C.M. (author), Pasman, W.J. (author), Stafleu, A. (author), Blom, W.A.M. (author), TNO Kwaliteit van Leven (author)
article 2007
Searched for: author%3A%22Pasman%2C+W.J.%22
(1 - 20 of 35)

Pages