Searched for: author%3A%22Montijn%2C+R.C.%22
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Wiese, M. (author), Schuren, F.H.J. (author), Smits, W.K. (author), Kuijpers, E.J. (author), Ouwens, A. (author), Heerikhuisen, M. (author), Vigsnaes, L. (author), van den Broek, T.J. (author), de Boer, P. (author), Montijn, R.C. (author), Vossen, J.M.B.M. (author)
Background: Clostridioides difficile is a Gram-positive anaerobic bacterium that can produce the toxins TcdA and/or TcdB and is considered an opportunistic pathogen. C. difficile is mainly transmitted as endospores, which germinate to produce the pathogenic vegetative cells under suitable conditions in the gut. To efficiently screen novel...
article 2022
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van der Vossen, J.M.B.M. (author), Fawzy, A. (author), Ouwens, A.M.T. (author), Doornmalen, J.C.P.M. (author), de Samber, M. (author), Driessens, R. (author), Heerikhuisen, M. (author), Montijn, R.C. (author)
Background The global COVID-19 pandemic, accompanied by spikes in the number of patients in hospitals, required substantial amounts of respiratory protective devices (respirators), thereby causing shortages. Disinfection of used respirators by applying ultraviolet C (UVC) light may enable safe reuse, reducing shortages. Aim To determine whether...
article 2022
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Keijser, B.J.F. (author), Agamennone, V. (author), van den Broek, T.J. (author), Caspers, M. (author), van de Braak, A. (author), Bomers, R. (author), Havekes, M. (author), Schoen, E. (author), van Baak, M. (author), Mioch, D. (author), Bomers, L. (author), Montijn, R.C. (author)
Background: Antibiotic therapy is commonly used in animal agriculture. Antibiotics excreted by the animals can contaminate farming environments, resulting in long term exposure of animals to sub-inhibitory levels of antibiotics. Little is known on the effect of this exposure on antibiotic resistance. In this study, we aimed to investigate the...
article 2019
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Botschuijver, S. (author), Welting, O. (author), Levin, E. (author), Maria-Ferreira, D. (author), Koch, E. (author), Montijn, R.C. (author), Seppen, J. (author), Hakvoort, T.B.M. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), van den Wijngaard, R.M. (author)
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder associated with altered gastrointestinal microflora and increased nociception to colonic distension. This visceral hypersensitivity can be reversed in our rat maternal separation model by fungicides. Menthacarin® is a proprietary combination of essential oils from...
article 2018
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Keijser, B.J.F. (author), van den Broek, T.J. (author), Slot, D.E. (author), van Twillert, L. (author), Kool, J. (author), Thabuis, C. (author), Ossendrijver, M. (author), van der Weijden, F.A. (author), Montijn, R.C. (author)
Background: The oral cavity harbors a complex microbial ecosystem, intimately related to oral health and disease. The use of polyol-sweetened gum is believed to benefit oral health through stimulation of salivary flow and impacting oral pathogenic bacteria. Maltitol is often used as sweetener in food products. This study aimed to establish the...
article 2018
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de Boer, P. (author), Rahaoui, H. (author), Leer, R.J. (author), Montijn, R.C. (author), van der Vossen, J.M.B.M. (author)
The major disadvantage of the current gold standard for detection of the food pathogen Campylobacter, i.e. culturing, is the lengthy procedure. In this study we assessed the use of real-time PCR for detection of Campylobacter. To this end, 926 poultry samples, taken from transport containers and broiler caeca in The Netherlands in 2007, were...
article 2015
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Lukovac, S. (author), Belzer, C. (author), Pellis, L. (author), Keijser, B.J. (author), de Vos, W.M. (author), Montijn, R.C. (author), Roeselers, G. (author)
The gut microbiota is essential for numerous aspects of human health. However, the underlying mechanisms of many host-microbiota interactions remain unclear. The aim of this study was to characterize effects of the microbiota on host epithelium using a novel ex vivo model based on mouse ileal organoids. We have explored the transcriptional...
article 2014
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de Oliveira, J.E. (author), van der Hoeven-Hangoor, E. (author), van de Linde, I.B. (author), Montijn, R.C. (author), van der Vossen, J.M.B.M. (author)
The feasibility of establishing probiotic bacteria in the intestine of broiler chickens by in ovo inoculation was investigated, followed by verifying possible subsequent protection against Salmonella Enteriditis infection. In a first study, 7 commercially available probiotics were screened for compatibility with in ovo inoculation. Two of these...
article 2014
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Zhao, Y. (author), Caspers, M.P.M. (author), Metselaar, K.I. (author), de Boer, P. (author), Roeselers, G. (author), Moezelaar, R. (author), Groot, M.N. (author), Montijn, R.C. (author), Abee, T. (author), Korta, R. (author)
One of the major concerns in the production of dairy concentrates is the risk of contamination by heat-resistant spores from thermophilic bacteria. In order to acquire more insight in the composition of microbial communities occurring in the dairy concentrate industry, a bar-coded 16S amplicon sequencing analysis was carried out on milk, final...
article 2013
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van der Hoeven-Hangoor, E. (author), van der Vossen, J.M.B.M. (author), Schuren, F.H.J. (author), Verstegen, M.W.A. (author), de Oliveira, J.E. (author), Montijn, R.C. (author), Hendriks, W.H. (author)
Microbiota plays a role in the release and absorption of nutrients from feed components, thereby affecting digesta composition and moisture content of the excreta. The objective of the current study was to determine the effects of 5 different diets varying in ingredients (medium-chain fatty acids, nonstarch polysaccharides, and starch) on the...
article 2013
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Ladirat, S.E. (author), Schols, H.A. (author), Nauta, A. (author), Schoterman, M.H.C. (author), Keijser, B.J.F. (author), Montijn, R.C. (author), Gruppen, H. (author), Schuren, F.H.J. (author)
Antibiotic treatments can lead to a disruption of the human microbiota. In this in-vitro study, the impact of antibiotics on adult intestinal microbiota was monitored in a new high-throughput approach: a fermentation screening-platform was coupled with a phylogenetic microarray analysis (Intestinal-chip). Fecal inoculum from healthy adults was...
article 2013
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Crielaard, W. (author), Zaura, E. (author), Schuller, A.A. (author), Huse, S.M. (author), Montijn, R.C. (author), Keijser, B.J.F. (author)
BACKGROUND: An understanding of the relation of commensal microbiota to health is essential in preventing disease. Here we studied the oral microbial composition of children (N = 74, aged 3 - 18 years) in natural transition from their deciduous to a permanent dentition and related the microbial profiles to their oral health status. The microbial...
article 2011
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Caspers, M.P.M. (author), Schuren, F.H.J. (author), van Zuijlen, A.C.M. (author), Brul, S. (author), Montijn, R.C. (author), Abee, T. (author), Kort, R. (author)
Failure of food preservation is frequently caused by thermostable spores of members of the Bacillaceae family, which show a wide spectrum of resistance to cleaning and preservation treatments. We constructed and validated a mixed-species genotyping array for 6 Bacillus species, including Bacillus subtilis, Bacillus licheniformis, Bacillus...
article 2011
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Paauw, A. (author), Caspers, M.P.M. (author), Leverstein-van Hall, M.A. (author), Schuren, F.H.J. (author), Montijn, R.C. (author), Verhoef, J. (author), Fluit, A.C. (author), TNO Kwaliteit van Leven (author)
Bacterial strains differ in their ability to cause hospital outbreaks. Using comparative genomic hybridization, Enterobacter cloacae complex isolates were studied to identify genetic markers specific for Enterobacter cloacae complex outbreak strains. No outbreak-specific genes were found that were common in all investigated outbreak strains....
article 2009
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Keijser, B.J.F. (author), Zaura, E. (author), Huse, S.M. (author), van der Vossen, J.M.B.M. (author), Schuren, F.H.J. (author), Montijn, R.C. (author), ten Gate, J.M. (author), Crielaard, W. (author), TNO Kwaliteit van Leven (author)
A good definition of commensal microflora and an understanding of its relation to health are essential in preventing and combating disease. We hypothesized that the species richness of human oral microflora is underestimated. Saliva and supragingival plaque were sampled from 71 and 98 healthy adults, respectively. Amplieons from the V6...
article 2008
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TNO Kwaliteit van Leven (author), Paauw, A. (author), Caspers, M.P.M. (author), Schuren, F.H.J. (author), Leverstein-van Hall, M.A. (author), Delétoile, A. (author), Montijn, R.C. (author), Verhoef, J. (author), Fluit, A.C. (author)
Background: Isolates of the Enterobacter cloacae complex have been increasingly isolated as nosocomial pathogens, but phenotypic identification of the E. cloacae complex is unreliable and irreproducible. Identification of species based on currently available genotyping tools is already superior to phenotypic identification, but the taxonomy of...
article 2008
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TNO Kwaliteit van Leven (author), Brul, S. (author), van der Spek, H. (author), Keijser, B.J. (author), Schuren, F.H. (author), Oomes, S.J. (author), Montijn, R.C. (author)
bookPart 2008
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Vlaminckx, B.J.M. (author), Schuren, F.H.J. (author), Montijn, R.C. (author), Caspers, M.P.M. (author), Beitsma, M.M. (author), Wannet, W.J.B. (author), Schouls, L.M. (author), Verhoef, J. (author), Jansen, W.T.M. (author), TNO Kwaliteit van Leven (author)
Invasive group A streptococcal (GAS) disease reemerged in The Netherlands in the late 1980s. To seek an explanation for this resurgence, the genetic compositions of 22 M1 and 19 M28 GAS strains isolated in The Netherlands between 1960s and the mid-1990s were analyzed by using a mixed-genome DNA microarray. During this four-decade period, M1 and...
article 2007
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Vlaminckx, B.J.M. (author), Schuren, F.H.J. (author), Montijn, R.C. (author), Caspers, M.P.M. (author), Fluit, A.C. (author), Wannet, W.J.B. (author), Schouls, L.M. (author), Verhoef, J. (author), Jansen, W.T.M. (author), TNO Kwaliteit van Leven (author)
Group A streptococci (GAS), or Streptococcus pyogenes, are associated with a remarkable variety of diseases, ranging from superficial infections to life-threatening diseases such as toxic-shock-like syndrome (TSS). GAS strains belonging to M types M1 and M3 are associated with TSS. This study aims to obtain insight into the gene profiles...
article 2007
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Schuren, H.J. (author), Montijn, R.C. (author), Oomes, S.J.C.M. (author), Brul, S. (author), Thijssen, J. (author), van Zuijlen, A. (author), Brul, S. (author), TNO Kwaliteit van Leven (author)
article 2006
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