The impact of preschool wheezing patterns on health-related quality of life at age 4 years pattern of pulmonary adenocarcinoma

We assessed whether dynamic preschool wheezing patterns affect health-related quality of life (HRQOL) at age 4 years. The study included 3878 children participating a prospective cohort study. Information on preschool wheezing was obtained by questionnaire and children were categorised into: never, early, late and persistent wheezing. At age 4...

Preschool physical activity and functional constipation: The generation r study

OBJECTIVES:: Decreased physical activity levels in children may partly explain the rising prevalence of functional constipation in childhood. The aim of the present study, therefore, was to examine the association between physical activity and functional constipation during the preschool period. METHODS:: This study was embedded in the...

Correlates of physical activity in 2-year-old toddlers: The generation R study

Objective: To describe and identify correlates of objectively measured physical activity and sedentary behavior in 2-year-old toddlers. Study design: A total of 347 children participating in a birth cohort study wore a unaxial ActiGraph accelerometer during 1 weekday and 1 weekend day. Information on potential correlates was assessed by parent...

The role of prenatal, perinatal and postnatal factors in the explanation of socioeconomic inequalities in preschool asthma symptoms: The generation R study

Background The authors assessed whether socioeconomic inequalities in asthma symptoms were already present in preschool children and to what extent prenatal, perinatal and postnatal risk factors for asthma symptoms mediate the effect of socioeconomic status (SES). Methods The study included 3136 Dutch children participating in the Generation R...

Asthma-like symptoms in the first year of life and health-related quality of life at age 12 months: The Generation R study

Purpose: This study compares HRQOL among subgroups of infants with asthma-like symptoms to a subgroup without such symptoms and examines independent associations between asthma-like symptoms during the first year of life and HRQOL at age 12 months. Methods: Our study sample included 5,000 infants participating in the Generation R study. Their...

Factors increasing the caries risk of second primary molars in 5-year-old Dutch children

International Journal of Paediatric Dentistry 2010; 20: 151-157 Background: Caries is still a prevalent condition in 5-year-old children. At present, knowledge regarding some aetiological factors, like deciduous molar hypomineralization (DMH), is limited. Aim: To investigate aetiological factors both directly and indirectly associated with...

A comparison of parent-reported wheezing or shortness of breath among infants as assessed by questionnaire and physician-interview: The generation R study

Purpose: The prevalence of asthma symptoms among preschool children is difficult to determine with accuracy because no gold standard is available for diagnosis. The aim of this study was to compare parent-reported wheezing or shortness of breath among infants as assessed by questionnaire and physician-interview. Methods: We studied 1,202...

The diagnostic work up of growth failure in secondary health care ; An evaluation of consensus guidelines

Background: As abnormal growth might be the first manifestation of undetected diseases, it is important to have accurate referral criteria and a proper diagnostic work-up. In the present paper we evaluate the diagnostic work-up in secondary health care according to existing consensus guidelines and study the frequency of underlying medical...

Feasibility and reliability of a mailed questionnaire to obtain visual analogue scale valuations for health states defined by the health utilities index mark 3

To establish the generalizability (external validity) of the Health Utilities Index Mark 3 (HUI3) as a single-summary score generic outcome measure in numerous countries/subgroups (including children), repeated studies of community preferences should be performed in various settings. In performing multiple HUI3 studies, a mailed questionnaire...