document

Heterologous gene expression in Lactobacillus

Posno, M. (author), Kottenhagen, M. (author), Lokman, B.C. (author), Jore, J. (author), Leer, R.J. (author), Pouwels, P.H. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

conference paper 1994

document

Structural and functional analysis of plasmid vectors for Lactobacillus

Leer, R.J. (author), van Luijk, N. (author), Posno, M. (author), Pouwels, P.H. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

conference paper 1994

document

Strategies for the over-production of fungal proteins in Aspergillus

van den Hondel, C.A.M.J.J. (author), Punt, P.J. (author), van Gorcom, R.F.M. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

conference paper 1994

document

Heterologous gene expression in Aspergillus

van Gorcom, R.F.M. (author), Punt, P.J. (author), van den Hondel, C.A.M.J.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

bookPart 1994

document

Genetic engineering of Lactobacilli, Leuconostocs, and Streptococcus thermophilus

Mercenier, A. (author), Pouwels, P.H. (author), Chassy, B.M. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

bookPart 1994

document

The effect of multiple copies of the upstream region of the Aspergillus niger glucoamylase-encoding gene on expression

Verdoes, J.C. (author), Punt, P.J. (author), Stouthamer, A.H. (author), van den Hondel, C.A.M.J.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

The regulation of transcription of the glucoamylase-encoding gene (glaA) of Aspergillus niger was studied. To facilitate this study a reporter strain containing a fusion of the glaA promoter (P(glaA)) of A. niger to the β- glucuronidase-encoding gene (uidA) of Escherichia coli was constructed. To analyze whether regulatory proteins are involved...

article 1994

document

Mid-frequency hearing loss and reduction of acoustic startle responding in rats following trichloroethylene exposure

Jaspers, R.M.A. (author), Muijser, H. (author), Lammers, J.H.C.M. (author), Kulig, B.M. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

Modification of auditory evoked startle responding using prepulse inhibition was used to examine the effects of trichloroethylene (TCE) exposure on auditory thresholds. Rats were exposed by inhalation to 0, 1500, or 3000 ppm TCE for 18 hours per day, 5 days a week for 3 weeks. Auditory thresholds for 5 and 20 kHz tones were measured before...

article 1993

document

Prenatal aroclor 1254 exposure selectively alters regional glial fibrillary acidic protein levels in the rat brain

Morse, D.C. (author), Wesseling, W. (author), Brouwer, A. (author), van den Berg, K.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

conference paper 1993

document

Growth and product formation in chemostat and recycling cultures by Aspergillus niger N402 and a glucoamylase overproducing transformant, provided with multiple copies of the glaA gen

Schrickx, J.M. (author), Krave, A.S. (author), Verdoes, J.C. (author), van den Hondel, C.A.M.J.J. (author), Stouthamer, A.H. (author), van Verseveld, H.W. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

Flow cytometric immunofluorescence assay for quantification of cyclobutyldithymine dimers in separate phases of the cell cycle

Berg, R.J.W. (author), de Gruijl, F.R. (author), Roza, L. (author), van der Leun, J.C. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

Effecten van neurotoxische stoffen

Jaspers, R.M.A. (author), Hooisma, J. (author), Kulig, B.M. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

bookPart 1993

document

Determination of the photoprotective efficacy of a topical sunscreen against UVB-induced DNA damage in human epidermis

van Praag, M.C.G. (author), Roza, L. (author), Boom, B.W. (author), Outluijting, C. (author), Bergen Henegouwen, J.B.A. (author), Vermeer, B.J. (author), Mommaas, A.M. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

Hexachlorobenzene-induced hypothyroidism: Involvement of different mechanisms by parent compound and metabolite

van Raaij, J.A.G.M. (author), Frijters, C.M.G. (author), van den Berg, K.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

Long-term changes in glial fibrillary acidic protein and calcium levels in rat hippocampus after a single systemic dose of kainic acid

van den Berg, K.J. (author), Gramsbergen, J.B.P. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

Chemicals/CAS: calcium, 7440-70-2; kainic acid, 487-79-6; Biological Markers; Calcium, 7440-70-2; Glial Fibrillary Acidic Protein; Kainic Acid, 487-79-6; Neurotoxins

article 1993

document

Use of Lactobacillus, a gras (generally regarded as safe) organism, as a base for a new generation of oral live vaccines

Claassen, E. (author), Kottenhagen, M.J. (author), Pouwels, P.H. (author), Posno, M. (author), Boersma, W.J.A. (author), Lucas, C.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

Glucoamylase overexpression in Aspergillus niger: Molecular genetics analysis of strains containing multiple copies of the glaA gene

Verdoes, J.C. (author), Punt, P.J. (author), Schrickx, J.M. (author), van Verseveld, H.W. (author), Stouthamer, A.H. (author), van den Hondel, C.A.M.J.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

A transformant of Aspergillus fumigatus deficient in the antigenic cytotoxin ASPFI

Paris, S. (author), Monod, M. (author), Diaquin, M. (author), Lamy, B. (author), Arruda, L.K. (author), Punt, P.J. (author), Latge, J.P. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

S-layer protein of Lactobacillus acidophilus ATCC 4356 purification, expression in Escherichia coli, and nucleotide sequence of the corresponding gene

Boot, H.J. (author), Kolen, K.P.A.M. (author), van Noort, J.M. (author), Pouwels, P.H. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

Glucuronidation of thyroid hormone in rat liver: Effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions

Visser, T.J. (author), Kaptein, E. (author), van Raaij, J.A.G.M. (author), van den Berg, K.J. (author), Tjong Tjin Joe, C. (author), van Engelen, G.M. (author), Brouwer, A. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993

document

Cloning, characterization and overexpression of the phytase-encoding gene (phyA) of Aspergillus niger

van Hartingsveldt, W. (author), van Zeijl, C.M.J. (author), Harteveld, G.M. (author), Gouka, R.J. (author), Suykerbuyk, M.E.G. (author), Luiten, R.G.M. (author), van Paridon, P.A. (author), Selten, G.C.M. (author), Veenstra, A.E. (author), van Gorcom, R.F.M. (author), van den Hondel, C.A.M.J.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1993