Searched for: author:"Mattern, I.E."
(1 - 15 of 15)
document
Broekhuijsen, M.P. (author), Mattern, I.E. (author), Contreras, R. (author), Kinghorn, J.R. (author), van den Hondel, C.A.M.J.J. (author), Medisch Biologisch Laboratorium TNO Centraal Instituut voor Voedingsonderzoek TNO (author)
article 1993
document
Mattern, I.E. (author), van Noort, J.M. (author), van den Berg, P. (author), Archer, D.B. (author), Roberts, I.N. (author), van den Hondel, C.A.M.J.J. (author), Medisch Biologisch Laboratorium TNO (author)
In the present study, the extracellular protease activity in a strain of the filamentous fungus Aspergillus niger was investigated and mutant strains deficient in the production of extracellular proteases were isolated. The major protease, which is responsible for 80-85% of the total activity, is aspergillopepsin A, a protein of ca. 43 kDa, the...
article 1992
document
van Noort, J.M. (author), van den Berg, P. (author), Mattern, I.E. (author), Medisch Biologisch Laboratorium TNO (author)
A method for the visualization of individual proteases within a complex biological sample is described. In a single chromatographic step, proteases can be separated from other biomolecules by selective binding to immobilized bacitracin, a peptide antibiotic. Following desorption, proteases may be separated by SDS-polyacrylamide gel...
article 1991
document
Anderson, D. (author), Green, M.H.L. (author), Mattern, I.E. (author), Godley, M.J. (author), Medisch Biologisch Laboratorium TNO (author)
article 1984
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Mattern, I.E. (author), Cocchiarella, L. (author), van Kralingen, C.G. (author), Lohman, P.H.M. (author), Medisch Biologisch Laboratorium TNO (author)
Eleven platinum compounds with nitrogen donor ligands, previously tested for anti-tumour activity were studied for induction of prophage lambda and for mutagenicity in the Ames assay, with various strains of Salmonella. The compounds included cis and trans isomers of Pt(II) and Pt(IV) complexes and were tested with and without metabolic...
article 1982
document
Mattern, I.E. (author), van der Zwaan, W. (author), Vink, G.J. (author), Medisch Biologisch Laboratorium TNO (author)
Chemicals/CAS: 4 nitroquinoline 1 oxide, 56-57-5; benzo[a]pyrene, 50-32-8; nitrofural, 59-87-0
article 1981
document
Wade, D.R. (author), Lohman, P.H.M. (author), Mattern, I.E. (author), Berends, F. (author), Medisch Biologisch Laboratorium TNO (author)
A commercial sample of the tuberculostatic drug isoniazid (INH) was found to have a weak mutagenic activity towards Salmonella typhimurium strains TA100 and TA1535. The addition of a rat or mouse liver homogenate to the test system decreased the mutagenic effect of INH. Hydrazine, an impurity of the INH sample, was also weakly mutagenic in...
article 1981
document
Vink, G.J. (author), Davis, P.B. (author), Hooftman, R.N. (author), Mattern, I.E. (author), Medisch Biologisch Laboratorium TNO (author)
Chemicals/CAS: aroclor, 12767-79-2; benzo[a]pyrene, 50-32-8; mesylic acid ethyl ester, 62-50-0; mesylic acid methyl ester, 66-27-3; triaziquone, 68-76-8
article 1981
document
Cocchiarella, L. (author), Mattern, I.E. (author), van Kralingen, C.G. (author), Medisch Biologisch Laboratorium TNO (author)
article 1980
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Seiler, J.P. (author), Mattern, I.E. (author), Green, M.H.L. (author), Anderson, D. (author), Medisch Biologisch Laboratorium TNO (author)
article 1980
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Mattern, I.E. (author), Greim, H. (author), Medisch Biologisch Laboratorium TNO (author)
Bacterial systems for the screening of chemical substances for mutagenic potential are receiving widespread attention. Now that many laboratories have introduced these test systems and a large number of substances has been tested, discrepancies in the results have become apparent. To discuss this problem, a workshop was organized at Neuherberg ...
article 1978
document
Mattern, I.E. (author), van der Zwaan, W.B. (author), Willems, M.J. (author), Medisch Biologisch Laboratorium TNO (author)
Chemicals/CAS: soybean oil, 8001-22-7; vinyl chloride, 75-01-4
article 1977
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Mattern, I.E. (author), Medisch biologisch laboratorium RVO-TNO Chemisch laboratorium TNO (author)
article 1977
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Mattern, I.E. (author), Medisch Biologisch Laboratorium RVO-TNO (author)
article 1976
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Rorsch, A. (author), van de Putte, P. (author), Mattern, I.E. (author), Zwenk, H. (author), van Sluis, C.A. (author), Medisch Biologisch Laboratorium TNO (author)
bookPart 1966
Searched for: author:"Mattern, I.E."
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